Chapter 34 Cellular Radiobiology Bushong: Radiologic Science for Technologists
MULTIPLE CHOICE
1. Irradiation hits occur through .
a. indirect effects
b. direct effects
c. excitation events
d. direct and indirect effects
ANS: D
Irradiation hits occur through both indirect and direct effects.
2. According to target theory, the target molecule of a cell is
. a. any molecule in the cell
b. the DNA in the nucleus
c. a water molecule
d. a protein macromolecule
ANS: B
According to target theory, the target molecule of a cell is the DNA in the nucleus.
3. A target molecule that is will always cause cell death.
a. inactivated
b. damaged
c. hit
, d. ionized
ANS: A
A target molecule that is inactivated will always cause cell death.
4. A hit to a cell target can occur from a(n) _ effect. a. indirect
b. direct
c. oxygen
d. indirect and direct
ANS: D
A hit to a cell target can occur from an indirect or direct effect.
5. The probability of a hit is increased with oxygen and LET radiation. a. high;
low
b. low; low
c. high; high
d. low; high
ANS: C
The probability of a hit is increased with high oxygen and high LET radiation.
6. The lethal effects of cell irradiation are measured by cell .
a. death
b. survival
, c. damage
d. mutation
ANS: B
The lethal effects of cell irradiation are measured by cell survival.
7. The -target, -hit model of radiation-induced cell death applies to simple cells
only.
a. single; single
b. multiple; multiple
c. multiple; single
d. single; multiple
ANS: A
The single-target, single-hit model of radiation-induced cell death applies to simple cells
only.
8. The DO represents the dose for human cells.
a. mean survival
b. mean lethal
c. 50% survival
d. 50% lethal
ANS: B
The DO represents the mean lethal dose for human cells.
9. Human cells are most radiosensitive during the phase of the cell cycle. a.
gap2
MULTIPLE CHOICE
1. Irradiation hits occur through .
a. indirect effects
b. direct effects
c. excitation events
d. direct and indirect effects
ANS: D
Irradiation hits occur through both indirect and direct effects.
2. According to target theory, the target molecule of a cell is
. a. any molecule in the cell
b. the DNA in the nucleus
c. a water molecule
d. a protein macromolecule
ANS: B
According to target theory, the target molecule of a cell is the DNA in the nucleus.
3. A target molecule that is will always cause cell death.
a. inactivated
b. damaged
c. hit
, d. ionized
ANS: A
A target molecule that is inactivated will always cause cell death.
4. A hit to a cell target can occur from a(n) _ effect. a. indirect
b. direct
c. oxygen
d. indirect and direct
ANS: D
A hit to a cell target can occur from an indirect or direct effect.
5. The probability of a hit is increased with oxygen and LET radiation. a. high;
low
b. low; low
c. high; high
d. low; high
ANS: C
The probability of a hit is increased with high oxygen and high LET radiation.
6. The lethal effects of cell irradiation are measured by cell .
a. death
b. survival
, c. damage
d. mutation
ANS: B
The lethal effects of cell irradiation are measured by cell survival.
7. The -target, -hit model of radiation-induced cell death applies to simple cells
only.
a. single; single
b. multiple; multiple
c. multiple; single
d. single; multiple
ANS: A
The single-target, single-hit model of radiation-induced cell death applies to simple cells
only.
8. The DO represents the dose for human cells.
a. mean survival
b. mean lethal
c. 50% survival
d. 50% lethal
ANS: B
The DO represents the mean lethal dose for human cells.
9. Human cells are most radiosensitive during the phase of the cell cycle. a.
gap2