Page 1 of 103
UAMS HEMATOLOGY EXAM NEWEST 2025 ACTUAL
EXAM TEST BANK| COMPLETE 500 REAL EXAM
QUESTIONS AND CORRECT VERIFIED ANSWERS/
ALREADY GRADED A+| UAMS HEMATOLOGY FINAL
EXAM PREP 2025 (BRAND NEW!!)
What is a macrocytic anemia we learned about? - ANSWER -
Megaloblastic anemia
What is defective in megaloblastic anemia? - ANSWER -Defective DNA
synthesis from B12 or folate; poor diet
What will the bone marrow show in megaloblastic anemia? - ANSWER
-Asynchrony, karryohexis, giant metamyelocytes, & bands
What are the laboratory results for megaloblastic anemia? - ANSWER -
Hypersegmented neutrophils, increased DBili, Bili, and LD, decreased
retic, pancytopenia
How is megaloblastic anemia treated? - ANSWER -Vitamin therapy
What tapeworm is associated with megaloblastic anemia? - ANSWER -
Diphyllobothrium latum
pg. 1
,Page 2 of 103
What are causes of folate deficient? - ANSWER -Alcoholism, poverty,
pregnancy,
What do you lack in pernicious anemia? - ANSWER -Intrinsic factor
What is the function of intrinsic factor? - ANSWER -Aids in B12
absorption
What test confirms pernicious anemia? - ANSWER -Schilling test
What are macrocytic cells associated with other than megaloblastic
anemia? - ANSWER -Liver disease, alcoholism, reticulocytosis,
What are causes of iron deficiency anemia? - ANSWER -Chronic blood
loss, poor diet, malabsorption,
What are the laboratory results for iron deficiency anemia? - ANSWER -
Decreased Fe, Ferritin, increased TIBC, increased retic only after
therapy
What are the laboratory findings for anemia of chronic disease? -
ANSWER -Decreased iron, TIBC, increased ferritin
pg. 2
,Page 3 of 103
What is the sequence of development in IDA? - ANSWER -1. Stores
depleted
2. Iron deficient erythropoiesis
3. Hgb/hct depletion
4. Symptoms appear
What is the treatment for IDA? - ANSWER -Treat underlying cause,
iron supplements (based on severity: oral, transfusion, injection)
What is hemosiderosis? - ANSWER -Increased iron in
reticuloendothelial cells
What is hemochromatosis? - ANSWER -More severe than
hemosiderosis, excess iron is stored in the liver
What is the treatment for hemochromatosis? - ANSWER -Phlebotomy or
chelation therapy to deplete iron stores
What are some microcytic anemias? - ANSWER -Iron deficiency
anemia, hemochromatosis, hemosiderosis thalassemia, anemia of
chronic disease, lead poisoning, sideroblastic anemia
What RBC inclusion is seen in lead poisoning? - ANSWER -Coarse
basophilic stippling
pg. 3
, Page 4 of 103
What happens in lead poisoning? - ANSWER -Lead blocks heme
production at several spots resulting in low heme production and low
hemoglobin
What is defective in sideroblastic anemia? - ANSWER -Abnormal heme
metabolism is present
What is defective in beta thalassemia? - ANSWER -Beta chains are
reduced or absent, alpha chains are increased
What is the most common descent for beta thalassemia? - ANSWER -
Mediterranean, South East Asians, and African American
What are the laboratory results for beta thalassemia? - ANSWER -Target
cells, basophilic stippling, increased A2 & F in hemoglobin
electrophoresis
What percent of transferrin is bound to iron? - ANSWER -30%
How is intravascular distinguished from extravascular hemolysis? -
ANSWER -Urine hemosiderin
What other tests are utilized in the detection of hemolytic anemia? -
ANSWER -Bilirubin, haptoglobin, urine hemosiderin
pg. 4
UAMS HEMATOLOGY EXAM NEWEST 2025 ACTUAL
EXAM TEST BANK| COMPLETE 500 REAL EXAM
QUESTIONS AND CORRECT VERIFIED ANSWERS/
ALREADY GRADED A+| UAMS HEMATOLOGY FINAL
EXAM PREP 2025 (BRAND NEW!!)
What is a macrocytic anemia we learned about? - ANSWER -
Megaloblastic anemia
What is defective in megaloblastic anemia? - ANSWER -Defective DNA
synthesis from B12 or folate; poor diet
What will the bone marrow show in megaloblastic anemia? - ANSWER
-Asynchrony, karryohexis, giant metamyelocytes, & bands
What are the laboratory results for megaloblastic anemia? - ANSWER -
Hypersegmented neutrophils, increased DBili, Bili, and LD, decreased
retic, pancytopenia
How is megaloblastic anemia treated? - ANSWER -Vitamin therapy
What tapeworm is associated with megaloblastic anemia? - ANSWER -
Diphyllobothrium latum
pg. 1
,Page 2 of 103
What are causes of folate deficient? - ANSWER -Alcoholism, poverty,
pregnancy,
What do you lack in pernicious anemia? - ANSWER -Intrinsic factor
What is the function of intrinsic factor? - ANSWER -Aids in B12
absorption
What test confirms pernicious anemia? - ANSWER -Schilling test
What are macrocytic cells associated with other than megaloblastic
anemia? - ANSWER -Liver disease, alcoholism, reticulocytosis,
What are causes of iron deficiency anemia? - ANSWER -Chronic blood
loss, poor diet, malabsorption,
What are the laboratory results for iron deficiency anemia? - ANSWER -
Decreased Fe, Ferritin, increased TIBC, increased retic only after
therapy
What are the laboratory findings for anemia of chronic disease? -
ANSWER -Decreased iron, TIBC, increased ferritin
pg. 2
,Page 3 of 103
What is the sequence of development in IDA? - ANSWER -1. Stores
depleted
2. Iron deficient erythropoiesis
3. Hgb/hct depletion
4. Symptoms appear
What is the treatment for IDA? - ANSWER -Treat underlying cause,
iron supplements (based on severity: oral, transfusion, injection)
What is hemosiderosis? - ANSWER -Increased iron in
reticuloendothelial cells
What is hemochromatosis? - ANSWER -More severe than
hemosiderosis, excess iron is stored in the liver
What is the treatment for hemochromatosis? - ANSWER -Phlebotomy or
chelation therapy to deplete iron stores
What are some microcytic anemias? - ANSWER -Iron deficiency
anemia, hemochromatosis, hemosiderosis thalassemia, anemia of
chronic disease, lead poisoning, sideroblastic anemia
What RBC inclusion is seen in lead poisoning? - ANSWER -Coarse
basophilic stippling
pg. 3
, Page 4 of 103
What happens in lead poisoning? - ANSWER -Lead blocks heme
production at several spots resulting in low heme production and low
hemoglobin
What is defective in sideroblastic anemia? - ANSWER -Abnormal heme
metabolism is present
What is defective in beta thalassemia? - ANSWER -Beta chains are
reduced or absent, alpha chains are increased
What is the most common descent for beta thalassemia? - ANSWER -
Mediterranean, South East Asians, and African American
What are the laboratory results for beta thalassemia? - ANSWER -Target
cells, basophilic stippling, increased A2 & F in hemoglobin
electrophoresis
What percent of transferrin is bound to iron? - ANSWER -30%
How is intravascular distinguished from extravascular hemolysis? -
ANSWER -Urine hemosiderin
What other tests are utilized in the detection of hemolytic anemia? -
ANSWER -Bilirubin, haptoglobin, urine hemosiderin
pg. 4
