ALU 301 Exam ACTUAL UPDATED Questions and CORRECT Answers
1. Cells that can recognize altered surface molecules on Answer 3: natural killer
mutated host cells as foreign and move to destroy the cells - page 3.
cell that carries them are:
1. complements
2. receptors
3. natural killer cells
4. mediators
2. All of the following are common examples of autoim- Answer 4: poliomyelitis -
mune disease EXCEPT: page 10.
1. Hashimoto's thyroiditis
2. systemic lupus erythematosus
3. Grave's thyroid disease
4. poliomyelitis
3. Which of the following statements regarding serum Answer 4: A, B, and C are
immunoglobulin levels is/are correct? correct - pages 8-9.
A. Monoclonal gammopathy has a risk for transforma-
tion into multiple myeloma.
B. Polyclonal gammopathy is frequently associated
with chronic infections.
C. Low serum globulin can indicate a primary immune
deficiency.
Answer Options:
1. A only is correct.
2. B only is correct.
3. A and C only are correct.
4. A, B, and C are correct.
,4. Describe the five cell types present in the white blood Refer to pages 7-8.
cell count and their basic function.
5. The severity of an HIV infection can be determined by: Answer 3: Refer to page 6.
A. T-helper cells (CD4 counts)
B. HIV viral load
C. basophil levels
Answer Options:
1. A only is correct.
2. B only is correct.
3. A and B only are correct.
4. A, B, and C are correct.
6. Describe the difference between immunotherapy and Refer to page 9.
immunosuppression.
7. The type of immune cell that differentiates in the bone Answer 4: B lymphocyte -
marrow is: page 4.
1. T-lymphocyte
2. helper T-cells
3. natural killer cells
4. B-lymphocyte
8. Which of the following statements regarding T-lym- Answer 2: A and B only are
phocytes is/are correct: correct - page 5-6.
A. One type is cytotoxic T-cells.
B. They eliminate infected cells.
C. They provide immunity by production of antibod-
ies.
, Answer Options:
1. A only is correct.
2. A and B only are correct.
3. B and C only are correct.
4. A, B, and C are correct.
9. Define and compare the innate and adaptive systems Refer to pages 1-7.
of immunity
10. Describe common variable immunodeficiency and the Refer to pages 10-11.
ways it affects the immune system.
11. The mainstay of treatment for acute mild to moderate Answer 2: 5-aminosalicy-
ulcerative colitis is: late compounds - page
26.
1. proton pump inhibitors
2. 5-aminosalicylate compounds
3. immunomodulators
4. biologic agents
12. All of the following statements regarding Crohn's dis- Answer 3: The most com-
ease are correct EXCEPT: mon presenting symptom
is a fistula - pages 21-22.
1. It involves inflammation of all layers of the bowel
wall.
2. It can involve nearby lymph nodes.
3. The most common presenting symptom is a fistula.
4. Skip lesions are often seen on endoscopy.
13. Which of the following statements regarding the can- Answer 3: B and C only are
cer risk with ulcerative colitis is/are correct? correct - pages 24-25.
A. The premalignant lesion is usually a polyp.
, B. The duration of disease is a risk factor.
C. A colectomy is recommended when dysplasia is
present.
Answer Options:
1. A only is correct.
2. A and B only are correct.
3. B and C only are correct.
4. A, B, and C are correct.
14. What clinical features can differentiate ulcerative coli- Refer to page 22.
tis from Crohn's disease?
15. Under what conditions can surgical therapy be cura- Refer to page 27.
tive for inflammatory bowel disease?
16. Deep linear ulcerations that are separated by normal Answer 1: skip lesions -
mucosa seen on imaging are: page 22.
1. skip lesions
2. bowel ischemia
3. celiac sprue
4. diverticulitis
17. Ulcerative colitis disease severity is determined by: Answer 3: endoscopy -
page 21.
1. age
2. recurrence
3. endoscopy
4. laboratory findings
18. All the following statements regarding ulcerative coli-
tis are correct EXCEPT:
1. Cells that can recognize altered surface molecules on Answer 3: natural killer
mutated host cells as foreign and move to destroy the cells - page 3.
cell that carries them are:
1. complements
2. receptors
3. natural killer cells
4. mediators
2. All of the following are common examples of autoim- Answer 4: poliomyelitis -
mune disease EXCEPT: page 10.
1. Hashimoto's thyroiditis
2. systemic lupus erythematosus
3. Grave's thyroid disease
4. poliomyelitis
3. Which of the following statements regarding serum Answer 4: A, B, and C are
immunoglobulin levels is/are correct? correct - pages 8-9.
A. Monoclonal gammopathy has a risk for transforma-
tion into multiple myeloma.
B. Polyclonal gammopathy is frequently associated
with chronic infections.
C. Low serum globulin can indicate a primary immune
deficiency.
Answer Options:
1. A only is correct.
2. B only is correct.
3. A and C only are correct.
4. A, B, and C are correct.
,4. Describe the five cell types present in the white blood Refer to pages 7-8.
cell count and their basic function.
5. The severity of an HIV infection can be determined by: Answer 3: Refer to page 6.
A. T-helper cells (CD4 counts)
B. HIV viral load
C. basophil levels
Answer Options:
1. A only is correct.
2. B only is correct.
3. A and B only are correct.
4. A, B, and C are correct.
6. Describe the difference between immunotherapy and Refer to page 9.
immunosuppression.
7. The type of immune cell that differentiates in the bone Answer 4: B lymphocyte -
marrow is: page 4.
1. T-lymphocyte
2. helper T-cells
3. natural killer cells
4. B-lymphocyte
8. Which of the following statements regarding T-lym- Answer 2: A and B only are
phocytes is/are correct: correct - page 5-6.
A. One type is cytotoxic T-cells.
B. They eliminate infected cells.
C. They provide immunity by production of antibod-
ies.
, Answer Options:
1. A only is correct.
2. A and B only are correct.
3. B and C only are correct.
4. A, B, and C are correct.
9. Define and compare the innate and adaptive systems Refer to pages 1-7.
of immunity
10. Describe common variable immunodeficiency and the Refer to pages 10-11.
ways it affects the immune system.
11. The mainstay of treatment for acute mild to moderate Answer 2: 5-aminosalicy-
ulcerative colitis is: late compounds - page
26.
1. proton pump inhibitors
2. 5-aminosalicylate compounds
3. immunomodulators
4. biologic agents
12. All of the following statements regarding Crohn's dis- Answer 3: The most com-
ease are correct EXCEPT: mon presenting symptom
is a fistula - pages 21-22.
1. It involves inflammation of all layers of the bowel
wall.
2. It can involve nearby lymph nodes.
3. The most common presenting symptom is a fistula.
4. Skip lesions are often seen on endoscopy.
13. Which of the following statements regarding the can- Answer 3: B and C only are
cer risk with ulcerative colitis is/are correct? correct - pages 24-25.
A. The premalignant lesion is usually a polyp.
, B. The duration of disease is a risk factor.
C. A colectomy is recommended when dysplasia is
present.
Answer Options:
1. A only is correct.
2. A and B only are correct.
3. B and C only are correct.
4. A, B, and C are correct.
14. What clinical features can differentiate ulcerative coli- Refer to page 22.
tis from Crohn's disease?
15. Under what conditions can surgical therapy be cura- Refer to page 27.
tive for inflammatory bowel disease?
16. Deep linear ulcerations that are separated by normal Answer 1: skip lesions -
mucosa seen on imaging are: page 22.
1. skip lesions
2. bowel ischemia
3. celiac sprue
4. diverticulitis
17. Ulcerative colitis disease severity is determined by: Answer 3: endoscopy -
page 21.
1. age
2. recurrence
3. endoscopy
4. laboratory findings
18. All the following statements regarding ulcerative coli-
tis are correct EXCEPT:
