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MMSC 433 Final Practice Questions with 100% Verified
Answers UPDATED!!!
What is the plasma carrier protein for iron?
transferrin
What type of iron is incorporated into the Heme moiety in
erythropoiesis?
ferrous
What is the Hallmark of Sideroblastic Anemia?
presence of ringed sideroblasts
What does the term "folate trap" refer to?
when vitamin B12 is deficient, more folate becomes trapped as
5-methyl THF
What is the relationship between hepcidin and ferroportin?
an increase in hepcidin results in inactive ferroportin
Which of the following parameters can be increased in the
Anemia of Chronic Inflammation?
serum ferritin
Which of the following parameters can be increased in iron
deficiency anemia?
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TIBC
Why is methylmalonic acid increased in vitamin B12 deficiency?
vitamin B12 catalyzes the conversion of methylmalonic
coenzyme A to succinyl Coenzyme A
What is the major metabolically available storage form of iron in
the body?
ferritin
The total iron binding capacity (TIBC) of the serum is an indirect
measure of which iron related protein?
transferrin
iron is transported out of macrophages, hepatocytes, and
enterocytes by what membrane protein?
ferroportin
The transfer of iron from enterocyte into the plasma is
regulated by:
hepcidin
What is the stain that is used to visualize iron in tissues and
bone marrow?
Prussian Blue
What would you expect for someone with stage 1 IDA?
asymptomatic but serum ferritin low
MMSC 433 Final Practice Questions with 100% Verified
Answers UPDATED!!!
What is the plasma carrier protein for iron?
transferrin
What type of iron is incorporated into the Heme moiety in
erythropoiesis?
ferrous
What is the Hallmark of Sideroblastic Anemia?
presence of ringed sideroblasts
What does the term "folate trap" refer to?
when vitamin B12 is deficient, more folate becomes trapped as
5-methyl THF
What is the relationship between hepcidin and ferroportin?
an increase in hepcidin results in inactive ferroportin
Which of the following parameters can be increased in the
Anemia of Chronic Inflammation?
serum ferritin
Which of the following parameters can be increased in iron
deficiency anemia?
, 2|Page
TIBC
Why is methylmalonic acid increased in vitamin B12 deficiency?
vitamin B12 catalyzes the conversion of methylmalonic
coenzyme A to succinyl Coenzyme A
What is the major metabolically available storage form of iron in
the body?
ferritin
The total iron binding capacity (TIBC) of the serum is an indirect
measure of which iron related protein?
transferrin
iron is transported out of macrophages, hepatocytes, and
enterocytes by what membrane protein?
ferroportin
The transfer of iron from enterocyte into the plasma is
regulated by:
hepcidin
What is the stain that is used to visualize iron in tissues and
bone marrow?
Prussian Blue
What would you expect for someone with stage 1 IDA?
asymptomatic but serum ferritin low
