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MMSC433 Hematology 2 Exam 2 Questions with 100% Verified
Answers UPDATED!!!
The most common clinical application of flow cytometry is:
a. detection of fetomaternal hemorrhage
b. diagnosis of platelet disorders
c. differentiation of anemias
d. diagnosis of leukemias and lymphomas - ANSWER D
Which of the following would be an unexpected finding in
homozygous beta0 thalassemia?
a. normal Hb F
b. bone marrow erythroid hyperplasia
c. target cells
d. severe anemia - ANSWER A
a 13 yr old African American girl, was admitted to the hospital
appearing acutely ill with fever and abdominal pain. On physical
exam, an enlarged spleen was evident. Lab results were as
follows: Hgb 5 g/dL, Hct 15%, RBC 1.4 x 1012/L, WBC 2.2 x
109/L, Reticulocyte count 1%, Segs 62%, bands 12%,
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lymphocytes 19%, Monocytes 4%, Eosinophils 2%, basophils
1%, MCV 92%, MCHC 33%, Platelet count 400 x 109/L.
Hemoglobin electrophoresis at alkaline pH showed one band in
the HgbS position and one band in the Hgb C position. The
hemoglobins were quantified as 55% HgbS and 45% Hgb C + A2.
The solubility test was also positive. These results are consistent
with what disease process?
a. Hgb C trait
b. Sickle cell disease
c. Hgb SC disease
d. Hgb C disease - ANSWER C
what is the basic hemoglobin defect in the thalassemias?
a. a structurally normal globin chain is absent or produced at
lower levels
b. iron is not incorporated into the protoporphyrin ring to form
heme
c. heme is producted at a lower concentration
d. one of the globin chains has an amino acid substitution -
ANSWER A
Iron overload in severe beta thalassemia (major) patients is
primarily a consequence of:
MMSC433 Hematology 2 Exam 2 Questions with 100% Verified
Answers UPDATED!!!
The most common clinical application of flow cytometry is:
a. detection of fetomaternal hemorrhage
b. diagnosis of platelet disorders
c. differentiation of anemias
d. diagnosis of leukemias and lymphomas - ANSWER D
Which of the following would be an unexpected finding in
homozygous beta0 thalassemia?
a. normal Hb F
b. bone marrow erythroid hyperplasia
c. target cells
d. severe anemia - ANSWER A
a 13 yr old African American girl, was admitted to the hospital
appearing acutely ill with fever and abdominal pain. On physical
exam, an enlarged spleen was evident. Lab results were as
follows: Hgb 5 g/dL, Hct 15%, RBC 1.4 x 1012/L, WBC 2.2 x
109/L, Reticulocyte count 1%, Segs 62%, bands 12%,
, 2|Page
lymphocytes 19%, Monocytes 4%, Eosinophils 2%, basophils
1%, MCV 92%, MCHC 33%, Platelet count 400 x 109/L.
Hemoglobin electrophoresis at alkaline pH showed one band in
the HgbS position and one band in the Hgb C position. The
hemoglobins were quantified as 55% HgbS and 45% Hgb C + A2.
The solubility test was also positive. These results are consistent
with what disease process?
a. Hgb C trait
b. Sickle cell disease
c. Hgb SC disease
d. Hgb C disease - ANSWER C
what is the basic hemoglobin defect in the thalassemias?
a. a structurally normal globin chain is absent or produced at
lower levels
b. iron is not incorporated into the protoporphyrin ring to form
heme
c. heme is producted at a lower concentration
d. one of the globin chains has an amino acid substitution -
ANSWER A
Iron overload in severe beta thalassemia (major) patients is
primarily a consequence of:
