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KU BIOL 600 Exam 4 Questions with Detailed
Verified Answers
Question: the second round of fa synthesis involves the condensation
reaction of __________ and __________
Ans✅ ✅: malonyl acp, butyryl acp
Question: the reaction of acetyl acp with malonyl acp produces a
__________ compound calledacetoacetyl acp
Ans✅ ✅: 4 c
Question: fa synthesis requires what for molecules
Ans✅ ✅: acetyl coa, atp, co2, nadph
Question: fa synthase is multifunctional enzyme where all the
components are located on a polypeptide chin but exists a __________
dimer
Ans✅ ✅: single, homo
Question: the er performs what two key functions in fa synthesis
Ans✅ ✅: elongation past c16, introduces double bonds into saturated fa
Question: phosphatidate is converted to __________ as the active
precursor to the synthesis of cadiolipin and phosphotidylinositol 4,5-
bisphosphate
Ans✅ ✅: cdp diacylglycerol
Question: if an alcohol is the active precursor and not diacylglycerol,
the phospholipids __________ and __________ are synthesized
Ans✅ ✅: phosphatidylethanoalamine, phosphatidylcholine
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Question: ceramide has __________ as its backbone structure instead
of glycerol
Ans✅ ✅: sphingosine
Question: the key regulatory enzyme in lipid synthesis is
Ans✅ ✅: phosphatidic acid phosphatase
Question: what are the three stages of cholesterol
Ans✅ ✅: mevalonate to isopentyl pyrophosphate, six molecules of isopentyl
pyrophosphate are condensed to squalene, squalene is cyclized and converted into
cholesterol
Question: how does the formation of ketone bodies contribute to
cholesterol synthesis
Ans✅ ✅: with the breakdown of fatty acids into ketone bodies which are then
converted to acetoacetyl coa, which can then react with acetyl coa to form the
precursor of cholesterol, called hmc coa
Question: one regulation method is transcriptional regulation. describe
this process when cholesterol levels are low
Ans✅ ✅: when cholesterol levels are low the scap protein attached to the srebp
proteins move to the golgi complex where the srebp is cleaved twice to cleave off the
sre. sre then moves to the nucleus and binds to dna resulting in the increase of those
enzymes involved in cholesterol production
Question: what separates ldl's from hdl's
Ans✅ ✅: ldl's have a higher lipid/protein ratio than hdl's
Question: ldl's are delivered into the cellular cytoplasm by what method
Ans✅ ✅: receptor mediated endocytosis
Question: what vitamin made from cholesterol uses sunlight for its
synthesis
KU BIOL 600 Exam 4 Questions with Detailed
Verified Answers
Question: the second round of fa synthesis involves the condensation
reaction of __________ and __________
Ans✅ ✅: malonyl acp, butyryl acp
Question: the reaction of acetyl acp with malonyl acp produces a
__________ compound calledacetoacetyl acp
Ans✅ ✅: 4 c
Question: fa synthesis requires what for molecules
Ans✅ ✅: acetyl coa, atp, co2, nadph
Question: fa synthase is multifunctional enzyme where all the
components are located on a polypeptide chin but exists a __________
dimer
Ans✅ ✅: single, homo
Question: the er performs what two key functions in fa synthesis
Ans✅ ✅: elongation past c16, introduces double bonds into saturated fa
Question: phosphatidate is converted to __________ as the active
precursor to the synthesis of cadiolipin and phosphotidylinositol 4,5-
bisphosphate
Ans✅ ✅: cdp diacylglycerol
Question: if an alcohol is the active precursor and not diacylglycerol,
the phospholipids __________ and __________ are synthesized
Ans✅ ✅: phosphatidylethanoalamine, phosphatidylcholine
, Page | 2
Question: ceramide has __________ as its backbone structure instead
of glycerol
Ans✅ ✅: sphingosine
Question: the key regulatory enzyme in lipid synthesis is
Ans✅ ✅: phosphatidic acid phosphatase
Question: what are the three stages of cholesterol
Ans✅ ✅: mevalonate to isopentyl pyrophosphate, six molecules of isopentyl
pyrophosphate are condensed to squalene, squalene is cyclized and converted into
cholesterol
Question: how does the formation of ketone bodies contribute to
cholesterol synthesis
Ans✅ ✅: with the breakdown of fatty acids into ketone bodies which are then
converted to acetoacetyl coa, which can then react with acetyl coa to form the
precursor of cholesterol, called hmc coa
Question: one regulation method is transcriptional regulation. describe
this process when cholesterol levels are low
Ans✅ ✅: when cholesterol levels are low the scap protein attached to the srebp
proteins move to the golgi complex where the srebp is cleaved twice to cleave off the
sre. sre then moves to the nucleus and binds to dna resulting in the increase of those
enzymes involved in cholesterol production
Question: what separates ldl's from hdl's
Ans✅ ✅: ldl's have a higher lipid/protein ratio than hdl's
Question: ldl's are delivered into the cellular cytoplasm by what method
Ans✅ ✅: receptor mediated endocytosis
Question: what vitamin made from cholesterol uses sunlight for its
synthesis
