,MULTIPLE CHOICE xz
1. Which name identifies a drug listed by the US Food
xz xz xz xz xz xz xz xz xz
xz andDrug Administration (FDA)?
z
x xz xz
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C xz
The official name is the name under which a drug is
xz xz xz xz x z xz xz xz xz xz
listed by the FDA. The brand name, or trademark, is the
xz xz xz xz xz xz xz xz xz xz xz
name given to a drug by its manufacturer. The
xz xz xz xz xz xz xz xz xz
nonproprietary, or generic, name is provided by the
xz xz xz xz xz xz xz xz
United States Adopted Names Council.
xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 9 xz xz xz xz
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
xz xz xz xz xz xz xz
CareEnvironment TOP: Nursing Process Step: Assessment CON:
xz xz xz x z xz xz xz
Patient Education
xz xz
2. Which source contains information specific to nutritional supplements?
xz xz xz xz xz xz xz
a. USP Dictionary of USAN &International Drug Names
xz xz xz xz xz xz xz
b. Natural Medicines Comprehensive Database xz xz xz
c. United States Pharmacopoeia/National Formulary (USP NF)
xz xz xz xz xz
d. Drug Interaction Facts xz xz
ANS: C xz
United States Pharmacopoeia/National Formulary contains information specific to
xz xz xz xz xz xz xz
nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
xz xz xz xz xz xz xz xz xz xz xz xz
compilation of drugnames, pronunciation guide, and possible future FDA approved
xz xz xz xz xz xz xz xz xz xz xz
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
xz xz xz xz xz xz xz xz xz xz
Database contains
xz xz
evidence-based information on herbal medicines and herbal combination products; it does
xz xz xz xz xz xz xz xz xz xz
notinclude information specific to nutritional supplements. Drug Interaction Facts
xz z
x xz xz xz xz xz xz xz xz
contains comprehensive information on drug interaction facts; it does not include
xz xz xz xz xz xz xz xz xz xz xz
nutritional supplements.
xz xz
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: xz xz x z xz
3NAT: NCLEX Client Needs Category: Physiological Integrity
xz z
x xz xz xz xz xz xz
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
x z xz xz xz x z xz xz xz
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
xz xz xz xz xz xz xz xz xz xz xz xz xz
a. Drug Facts and Comparisons xz xz xz
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
xz xz xz xz xz xz xz xz 3
Edition
xz
b. Drug Interaction Facts xz xz
c. Handbook on Injectable Drugs xz xz xz
d. Martindale—The Complete Drug Reference xz xz xz
ANS: A xz
Drug Facts and Comparisons contains drug monographs that describe all drugs
xz xz xz xz xz xz xz xz xz xz
in atherapeutic class. Monographs are formatted as tables to allow comparison of
xz xz xz xz xz xz xz xz xz xz xz xz xz
similarproducts, brand names, manufacturers, cost indices, and available dosage
xz xz xz xz xz xz xz xz xz xz
forms Online version is available.
xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 xz xz x z xz xz xz
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
xz xz x z x z xz xz xz xz xz
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
x z xz xz xz x z xz xz xz xz xz xz
4. Which drug reference contains monographs about virtually every single-entity drug
xz xz xz xz xz xz xz xz xz
availablein the United States and describes therapeutic uses of drugs, including
xz xz xz xz xz xz xz xz xz xz xz xz
approved and unapproved uses?
xz xz xz xz
a. Martindale: The Complete Drug Reference xz xz xz xz
b. AHFS Drug Information xz xz
c. Drug Reference xz
d. Drug Facts and Comparisons xz xz xz
ANS: B xz
AHFS Drug Information contains monographs about virtually every single-entity drug
xz xz xz xz xz xz xz xz xz
available in the United States and describes therapeutic uses of drugs, including approved
xz xz xz xz xz xz xz xz xz xz xz xz xz
andunapproved uses.
xz z
x xz
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 xz xz x z xz xz xz
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
xz xz x z x z xz xz xz xz xz
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
x z xz xz xz x z xz xz xz xz xz xz
5. Which online drug reference makes available to healthcare providers and the public a
xz xz xz xz xz xz xz xz xz xz xz xz
standard, comprehensive, up-to-date look up and downloadable resource about
xz xz xz xz xz xz xz xz xz
medicines?
xz
a. American Drug Index xz xz
b. American Hospital Formulary xz xz
c. DailyMed
d. Drug Reference xz
ANS: C xz
DailyMed makes available to healthcare providers and the public a standard,
xz xz xz xz xz xz xz xz xz xz
comprehensive,up-to-date look up and downloadable resource about medicines. The
xz xz xz xz xz xz xz xz xz xz
American Drug Index isnot appropriate for patient use. The American Hospital
xz xz xz xz xz xz xz xz xz xz xz xz
Formulary is not appropriate for patient use. The drug reference is not appropriate for
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
patient use.
xz xz
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: xz xz x z xz xz xz xz
3NAT: NCLEX Client Needs Category: Physiological Integrity
xz z
x xz xz xz xz xz xz
TOP: Nursing Process Step: Implementation
xz xz xz xz
CON: Safety | Patient Education | Clinical Judgment
x z xz xz xz xz xz xz
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
a. Federal Food, Drug, and Cosmetic Act (1938) xz xz xz xz xz xz
b. Durham Humphrey Amendment (1952) xz xz xz
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
xz xz xz xz xz xz xz xz 4
Edition
xz
c. Controlled Substances Act (1970) xz xz xz
d. Kefauver Harris Drug Amendment (1962) xz xz xz xz
ANS: A xz
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
xz xz xz xz xz xz xz xz xz xz xz xz xz
the safety of all drugs before marketing. Later amendments and acts helped tighten
xz xz xz xz xz xz xz xz xz xz xz xz xz
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
xz xz xz xz xz xz xz xz xz xz xz xz
kinds of drugs that cannot be used safely without medical supervision and restricts their
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
sale to prescription by a licensed practitioner. The Controlled Substances Act addresses
xz xz xz xz xz xz xz xz xz xz xz xz
only controlled substances andtheir categorization. The Kefauver Harris Drug
xz xz xz xz z
x xz xz xz xz xz
Amendment ensures drug efficacy and greaterdrug safety. Drug manufacturers are
xz xz xz xz xz xz z
x xz xz xz xz
required to prove to the FDA the effectiveness of their products before marketing them.
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 xz xz xz xz xz xz
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological
x z xz xz xz xz xz
IntegrityTOP: Nursing Process Step: Assessment
xz xz xz xz xz xz
CON: Safety | Patient Education | Evidence | Health Care Law
x z xz xz xz xz xz xz xz xz xz
7. Which classification does meperidine (Demerol) fall under?
xz xz xz xz xz xz
a. I
b. II
c. III
d. IV
ANS: B xz
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
lead tosevere psychological and physical dependence. Schedule I drugs have high
xz xz xz xz xz xz xz xz xz xz xz xz
potential for abuseand no recognized medical use. Schedule III drugs have some
xz xz xz xz xz xz xz xz xz xz xz xz xz
potential for abuse. Use may lead to low to moderate physical dependence or high
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
psychological dependence. Schedule IVdrugs have low potential for abuse. Use may
xz xz xz xz z
x xz xz xz xz xz xz xz
lead to limited physical or psychological dependence.
xz xz xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: xz xz x z xz
2NAT: NCLEX Client Needs Category: Safe, Effective Care
xz z
x xz xz xz xz xz xz xz
Environment
xz
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
x z xz xz xz x z xz xz xz xz xz
8. Which action would the FDA take to expedite drug development and approval for an
xz xz xz xz xz xz xz xz xz xz xz xz xz
outbreakof smallpox?
xz xz xz
a. List smallpox as a health orphan disease.
xz xz xz xz xz xz
b. Omit the preclinical research phase. xz xz xz xz
c. Extend the clinical research phase. xz xz xz xz
d. Fast track the investigational drug.
xz xz xz xz
ANS: D xz
Once the Investigational New Drug Application has been approved, the drug can receive
xz xz xz xz xz xz xz xz xz xz xz xz
highest priority within the agency, which is called fast tracking. A smallpox outbreak
xz xz xz xz xz xz xz xz xz xz xz xz xz
would become a priority concern in the world. Orphan diseases are not researched in a
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
priority manner. Preclinical research is not omitted. Extending any phase of the research
xz xz xz xz xz xz xz xz xz xz xz xz xz
would meana longer time to develop a vaccine. The FDA must ensure that all phases of
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
the preclinical andclinical research phase have been completed in a safe manner.
xz xz xz xz xz xz xz xz xz xz xz xz xz
DIF: Cognitive Level: Knowledge xz xz REF: xz xz xz p. 7 xz OBJ: 5 xz
1. Which name identifies a drug listed by the US Food
xz xz xz xz xz xz xz xz xz
xz andDrug Administration (FDA)?
z
x xz xz
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C xz
The official name is the name under which a drug is
xz xz xz xz x z xz xz xz xz xz
listed by the FDA. The brand name, or trademark, is the
xz xz xz xz xz xz xz xz xz xz xz
name given to a drug by its manufacturer. The
xz xz xz xz xz xz xz xz xz
nonproprietary, or generic, name is provided by the
xz xz xz xz xz xz xz xz
United States Adopted Names Council.
xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 9 xz xz xz xz
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective
xz xz xz xz xz xz xz
CareEnvironment TOP: Nursing Process Step: Assessment CON:
xz xz xz x z xz xz xz
Patient Education
xz xz
2. Which source contains information specific to nutritional supplements?
xz xz xz xz xz xz xz
a. USP Dictionary of USAN &International Drug Names
xz xz xz xz xz xz xz
b. Natural Medicines Comprehensive Database xz xz xz
c. United States Pharmacopoeia/National Formulary (USP NF)
xz xz xz xz xz
d. Drug Interaction Facts xz xz
ANS: C xz
United States Pharmacopoeia/National Formulary contains information specific to
xz xz xz xz xz xz xz
nutritionalsupplements. USP Dictionary of USAN & International Drug Names is a
xz xz xz xz xz xz xz xz xz xz xz xz
compilation of drugnames, pronunciation guide, and possible future FDA approved
xz xz xz xz xz xz xz xz xz xz xz
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
xz xz xz xz xz xz xz xz xz xz
Database contains
xz xz
evidence-based information on herbal medicines and herbal combination products; it does
xz xz xz xz xz xz xz xz xz xz
notinclude information specific to nutritional supplements. Drug Interaction Facts
xz z
x xz xz xz xz xz xz xz xz
contains comprehensive information on drug interaction facts; it does not include
xz xz xz xz xz xz xz xz xz xz xz
nutritional supplements.
xz xz
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: xz xz x z xz
3NAT: NCLEX Client Needs Category: Physiological Integrity
xz z
x xz xz xz xz xz xz
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
x z xz xz xz x z xz xz xz
3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
xz xz xz xz xz xz xz xz xz xz xz xz xz
a. Drug Facts and Comparisons xz xz xz
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
xz xz xz xz xz xz xz xz 3
Edition
xz
b. Drug Interaction Facts xz xz
c. Handbook on Injectable Drugs xz xz xz
d. Martindale—The Complete Drug Reference xz xz xz
ANS: A xz
Drug Facts and Comparisons contains drug monographs that describe all drugs
xz xz xz xz xz xz xz xz xz xz
in atherapeutic class. Monographs are formatted as tables to allow comparison of
xz xz xz xz xz xz xz xz xz xz xz xz xz
similarproducts, brand names, manufacturers, cost indices, and available dosage
xz xz xz xz xz xz xz xz xz xz
forms Online version is available.
xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 xz xz x z xz xz xz
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
xz xz x z x z xz xz xz xz xz
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
x z xz xz xz x z xz xz xz xz xz xz
4. Which drug reference contains monographs about virtually every single-entity drug
xz xz xz xz xz xz xz xz xz
availablein the United States and describes therapeutic uses of drugs, including
xz xz xz xz xz xz xz xz xz xz xz xz
approved and unapproved uses?
xz xz xz xz
a. Martindale: The Complete Drug Reference xz xz xz xz
b. AHFS Drug Information xz xz
c. Drug Reference xz
d. Drug Facts and Comparisons xz xz xz
ANS: B xz
AHFS Drug Information contains monographs about virtually every single-entity drug
xz xz xz xz xz xz xz xz xz
available in the United States and describes therapeutic uses of drugs, including approved
xz xz xz xz xz xz xz xz xz xz xz xz xz
andunapproved uses.
xz z
x xz
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 xz xz x z xz xz xz
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
xz xz x z x z xz xz xz xz xz
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
x z xz xz xz x z xz xz xz xz xz xz
5. Which online drug reference makes available to healthcare providers and the public a
xz xz xz xz xz xz xz xz xz xz xz xz
standard, comprehensive, up-to-date look up and downloadable resource about
xz xz xz xz xz xz xz xz xz
medicines?
xz
a. American Drug Index xz xz
b. American Hospital Formulary xz xz
c. DailyMed
d. Drug Reference xz
ANS: C xz
DailyMed makes available to healthcare providers and the public a standard,
xz xz xz xz xz xz xz xz xz xz
comprehensive,up-to-date look up and downloadable resource about medicines. The
xz xz xz xz xz xz xz xz xz xz
American Drug Index isnot appropriate for patient use. The American Hospital
xz xz xz xz xz xz xz xz xz xz xz xz
Formulary is not appropriate for patient use. The drug reference is not appropriate for
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
patient use.
xz xz
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: xz xz x z xz xz xz xz
3NAT: NCLEX Client Needs Category: Physiological Integrity
xz z
x xz xz xz xz xz xz
TOP: Nursing Process Step: Implementation
xz xz xz xz
CON: Safety | Patient Education | Clinical Judgment
x z xz xz xz xz xz xz
6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
a. Federal Food, Drug, and Cosmetic Act (1938) xz xz xz xz xz xz
b. Durham Humphrey Amendment (1952) xz xz xz
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th
xz xz xz xz xz xz xz xz 4
Edition
xz
c. Controlled Substances Act (1970) xz xz xz
d. Kefauver Harris Drug Amendment (1962) xz xz xz xz
ANS: A xz
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
xz xz xz xz xz xz xz xz xz xz xz xz xz
the safety of all drugs before marketing. Later amendments and acts helped tighten
xz xz xz xz xz xz xz xz xz xz xz xz xz
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
xz xz xz xz xz xz xz xz xz xz xz xz
kinds of drugs that cannot be used safely without medical supervision and restricts their
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
sale to prescription by a licensed practitioner. The Controlled Substances Act addresses
xz xz xz xz xz xz xz xz xz xz xz xz
only controlled substances andtheir categorization. The Kefauver Harris Drug
xz xz xz xz z
x xz xz xz xz xz
Amendment ensures drug efficacy and greaterdrug safety. Drug manufacturers are
xz xz xz xz xz xz z
x xz xz xz xz
required to prove to the FDA the effectiveness of their products before marketing them.
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 xz xz xz xz xz xz
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological
x z xz xz xz xz xz
IntegrityTOP: Nursing Process Step: Assessment
xz xz xz xz xz xz
CON: Safety | Patient Education | Evidence | Health Care Law
x z xz xz xz xz xz xz xz xz xz
7. Which classification does meperidine (Demerol) fall under?
xz xz xz xz xz xz
a. I
b. II
c. III
d. IV
ANS: B xz
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
lead tosevere psychological and physical dependence. Schedule I drugs have high
xz xz xz xz xz xz xz xz xz xz xz xz
potential for abuseand no recognized medical use. Schedule III drugs have some
xz xz xz xz xz xz xz xz xz xz xz xz xz
potential for abuse. Use may lead to low to moderate physical dependence or high
xz xz xz xz xz xz xz xz xz xz xz xz xz xz
psychological dependence. Schedule IVdrugs have low potential for abuse. Use may
xz xz xz xz z
x xz xz xz xz xz xz xz
lead to limited physical or psychological dependence.
xz xz xz xz xz xz xz
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: xz xz x z xz
2NAT: NCLEX Client Needs Category: Safe, Effective Care
xz z
x xz xz xz xz xz xz xz
Environment
xz
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
x z xz xz xz x z xz xz xz xz xz
8. Which action would the FDA take to expedite drug development and approval for an
xz xz xz xz xz xz xz xz xz xz xz xz xz
outbreakof smallpox?
xz xz xz
a. List smallpox as a health orphan disease.
xz xz xz xz xz xz
b. Omit the preclinical research phase. xz xz xz xz
c. Extend the clinical research phase. xz xz xz xz
d. Fast track the investigational drug.
xz xz xz xz
ANS: D xz
Once the Investigational New Drug Application has been approved, the drug can receive
xz xz xz xz xz xz xz xz xz xz xz xz
highest priority within the agency, which is called fast tracking. A smallpox outbreak
xz xz xz xz xz xz xz xz xz xz xz xz xz
would become a priority concern in the world. Orphan diseases are not researched in a
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
priority manner. Preclinical research is not omitted. Extending any phase of the research
xz xz xz xz xz xz xz xz xz xz xz xz xz
would meana longer time to develop a vaccine. The FDA must ensure that all phases of
xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz xz
the preclinical andclinical research phase have been completed in a safe manner.
xz xz xz xz xz xz xz xz xz xz xz xz xz
DIF: Cognitive Level: Knowledge xz xz REF: xz xz xz p. 7 xz OBJ: 5 xz