Nephron Anatomy - Answers Structure affecting electrolyte and water reabsorption.
Diuretics - Answers Medications that increase urine output by blocking reabsorption.
Filtration Rate - Answers Kidneys create 125 mL/min of filtrate.
Proximal Convoluted Tubule - Answers Nephron segment with the greatest diuretic effect.
Loop Diuretics - Answers Act in loop of Henle to prevent Na reabsorption.
Lasix/Furosemide - Answers Loop diuretic for rapid fluid excretion.
Hyponatremia - Answers Low sodium levels, a potential adverse effect of diuretics.
Hydrochlorothiazide - Answers Thiazide diuretic blocking Na and Cl in early DCT.
Potassium-Sparing Diuretics - Answers Retain potassium while promoting moderate diuresis.
Spironolactone - Answers Aldosterone antagonist used to prevent K loss.
Triamterene - Answers Non-aldosterone antagonist with minimal diuresis.
Renin-Angiotensin-Aldosterone System (RAAS) - Answers Regulates blood volume and pressure
via hormone action.
Angiotensin Converting Enzyme (ACE) - Answers Converts angiotensin I to angiotensin II.
ACE Inhibitors (ACEIs) - Answers Medications that inhibit ACE to lower blood pressure.
Prodrugs - Answers Drugs requiring conversion to active form in the body.
Adverse Effects of ACEIs - Answers Includes hypotension, hyperkalemia, and renal impairment.
Angiotensin II Receptor Blockers (ARBs) - Answers Block angiotensin II effects to lower blood
pressure.
Drug Interactions - Answers Potential interactions affecting efficacy and safety of medications.
Electrolyte Imbalances - Answers Disruptions in sodium, potassium, or chloride levels.
Hypotension - Answers Low blood pressure due to volume loss from diuretics.
Cardiac Remodeling - Answers Structural changes in heart due to RAAS activation.
Volume Loss - Answers Decreased blood volume leading to dehydration symptoms.
Patient Teaching Points - Answers Important information for patients on diuretics and RAAS
drugs.