NBME CBSE (usmle step 1)MEDICAL *
a,- a,- a,- a,- a,-
NBME CBSE (usmle step 1)MEDICAL
ACTUAL EXAM NEWEST VERSION
2024-2025 TESTBANK QUESTIONS
AND CORRECT DETAILEDANSWERS
WITH RATIONALES
|ALREADYGRADED A+
ALREADYGRADED A+ a,-
70yoa,-Ma,-diesa,-ina,-aa,-motora,-vehiclea,-collision.a,-Wasa,-undergoinga,-evaluationa,-fora,-occulta,-
blooda,-ina,-thea,-stool.a,-Photoa,-ofa,-transversea,-colona,-shown.a,-Dx?✅Tubulara,-adenoma
38yoa,-Ma,-witha,-1-weeka,-hxa,-ofa,-watery,a,-itchya,-eyesa,-anda,-aa,-runnya,-nose.a,-Physicala,-showsa,-
inflameda,-nasala,-mucosa.a,-Noa,-congestiona,-ina,-lowera,-lung.a,-
Pharmacotherapy?✅Loratadine
16yoa,-girla,-witha,-3-daya,-hxa,-ofa,-fever,a,-nonproductivea,-cough,a,-anda,-fatigue.a,-Ta,-38.3,a,-Pa,-
88/min,a,-BPa,-102-70.a,-PEa,-showsa,-palea,-conjunctivae.a,-CXRa,-showsa,-bilaterala,-interstitiala,-
infiltrates.a,-Blooda,-spontaenouslya,-agglutinatesa,-whilea,-awaitinga,-transporta,-toa,-thea,-
laboratory.a,-Antibodya,-isotypesa,-causinga,-agglutination?✅IgM
24yoa,-Ma,-witha,-smalla,-tendera,-blistersa,-ona,-hisa,-penisa,-3a,-daysa,-aftera,-unprotecteda,-sex.a,-
Photographa,-shown.a,-Causala,-agent?✅HSV-2
42yoa,-Fa,-witha,-3-yeara,-hxa,-ofa,-ana,-intermittenta,-faciala,-rash,a,-includinga,-thea,-forehead,a,-
eyelids,a,-nose,a,-anda,-cheeks.a,-Rasha,-seemsa,-toa,-bea,-gettinga,-worsea,-sincea,-shea,-moveda,-
froma,-Newa,-Yorka,-toa,-Floridaa,-lasta,-year.a,-Spicya,-foodsa,-precipitatea,-aa,-flushinga,-reactiona,-
thata,-seemsa,-toa,-exacerbatea,-thea,-rash.a,-PEa,-showsa,-erythemaa,-overa,-thea,-nosea,-anda,-
cheeks,a,-witha,-scattereda,-telangiectasiasa,-anda,-aa,-fewa,-papules.a,-Dx?✅Rosacea
53yoa,-Ma,-returneda,-froma,-Africa,a,-hasa,-fever,a,-headache,a,-anda,-abdominala,-discomfort.a,-
Receiveda,-appropriatea,-vaccinationsa,-priora,-toa,-thea,-trip.a,-Ta,-39.4C.a,-Aa,-wright-staineda,-
peripherala,-smeara,-shown.a,-Dx?✅Malaria
68yoa,-Fa,-witha,-T2DMa,-anda,-hypertensiona,-thata,-hasa,-beena,-poorlya,-controlleda,-despitea,-
hydrochlorothiazidea,-treatment.a,-BPa,-150/96,a,-Labsa,-showa,-seruma,-glucosea,-concentrationa,-
,ofa,-130a,-anda,-proteinuria.a,-Ina,-additiona,-toa,-currenta,-Rx,a,-whicha,-isa,-mosta,-appropriatea,-
pharmacotherapy?✅Lisinopril
66yoa,-Ma,-witha,-stagea,-IVa,-colona,-cancera,-witha,-3-daya,-hxa,-ofa,-severea,-diarrheaa,-aftera,-
receivinga,-chemotherapya,-witha,-fluorouracil,a,-leucovorin,a,-anda,-Irinotecan.a,-prescribeda,-
opioida,-antidiarrheala,-agenta,-witha,-noa,-CNSa,-effects.a,-Whicha,-med?✅Loperamide
35yoa,-Ma,-ina,-EDa,-witha,-2-houra,-hxa,-ofa,-severa,-fatiguea,-anda,-dizziness.a,-Hada,-profuse,a,-waterya,-
diarrheaa,-fora,-8a,-hoursa,-despitea,-aa,-lacka,-ofa,-orala,-intake.a,-Recentlya,-returneda,-froma,-aa,-
medicala,-reliefa,-tripa,-toa,-aa,-removea,-villagea,-ina,-Honduras.a,-Ta,-36.7a,-C,a,-Pa,-122/min,a,-BPa,-
90/50.a,-PEa,-showsa,-drya,-skina,-anda,-decreaseda,-capillarya,-refill.a,-Stoola,-fora,-occulta,-blooda,-isa,-
negative;a,-stoola,-isa,-graya,-anda,-turbid.a,-Grama,-staina,-showsa,-gram-negative,a,-comma-
shapeda,-bacteria;a,-noa,-erythrocytesa,-ofa,-leukocytes.a,-MOAa,-ofa,-toxin?✅Activationa,-ofa,-
adenylyla,-cyclase
59yoa,-Fa,-witha,-graduala,-onseta,-ofa,-lacka,-ofa,-musclea,-controla,-ina,-hera,-lefta,-arma,-anda,-leg.a,-Sxa,-1a,-
moa,-agoa,-aftera,-dxa,-witha,-metastatica,-breasta,-cancer.a,-PEa,-showsa,-ataxiaa,-ofa,-lefta,-uppera,-
anda,-lowera,-extremities.a,-Musclea,-strength,a,-DTR,a,-sensation,a,-proprioceptiona,-normal.a,-
Metastatica,-tumora,-ina,-whicha,-location?✅cerebellum
Newborna,-delivereda,-ata,-38a,-weeks'a,-gestationa,-weighsa,-1800a,-g.a,-PEa,-showsa,-petechiala,-
rash,a,-microcephaly,a,-anda,-hepatosplenomegaly.a,-Serologica,-testa,-fora,-CMV:a,-IgGa,-+a,-ina,-
mother,a,-+a,-ina,-newborn;a,-IGMa,--a,-ina,-mother,a,-+a,-ina,-newborn.a,-Explanation?✅Congenitala,-
cytomegalovirusa,-infection
Femalea,-newborna,-isa,-delivereda,-ata,-38a,-weeks'a,-gestation.a,-Apgara,-8a,-anda,-8a,-ata,-1/5a,-min.a,-
PEa,-showsa,-aa,-bulging,a,-fluod0filleda,-massa,-approximatelya,-5a,-cma,-ina,-diametera,-ina,-thea,-
midlinea,-overa,-thea,-lumbosacrala,-region.a,-Noa,-spontaneousa,-movementsa,-ofa,-thea,-lowera,-
extremities.a,-Abnormalitya,-mosta,-likelya,-occurreda,-becausea,-ofa,-abnormala,-developmenta,-
duringa,-whicha,-periodsa,-ofa,-postconceptiona,-(ina,-days)?✅15a,-toa,-40
64yoa,-Ma,-ina,-EDa,-3a,-hoursa,-aftera,-SOBa,-witha,-exertiona,-anda,-extremea,-fatigue.a,-Hasa,-
ischemica,-hearta,-disease.a,-Pa,-125/min,a,-BPa,-105/60.a,-ECGa,-showsa,-atriala,-fibrillation.a,-
Intravenousa,-ibutilidea,-isa,-administered.a,-Tena,-minutesa,-later,a,-ECGa,-showsa,-normala,-sinusa,-
rhythm.a,-Riska,-fora,-whicha,-druga,-effecta,-ina,-thea,-nexta,-6a,-hours?✅torsadesa,-dea,-pointes
65yoa,-Fa,-witha,-20-yeara,-hxa,-ofa,-osteoarthritisa,-ofa,-thea,-handsa,-nowa,-hasa,-paina,-radiatinga,-
downa,-thea,-distala,-anteriora,-thigh,a,-knee,a,-mediala,-leg,a,-anda,-food.a,-Bonya,-outgrowtha,-ofa,-
vertebraea,-compressinga,-onea,-ofa,-thea,-spinala,-nervesa,-isa,-suspected.a,-Nervea,-roota,-ina,-
whicha,-intervertebrala,-foraminaa,-isa,-effected?✅L3a,-toa,-L4
38yoa,-Ma,-witha,-3-yeara,-hxa,-ofa,-T2DM.a,-Takinga,-ana,-orala,-antihyperglycemica,-agent,a,-hea,-hasa,-
trieda,-dieta,-anda,-exercise.a,-BMIa,-32.a,-PEa,-normal.a,-Hba,-A1ca,-isa,-10%.a,-Physiciana,-
recommendsa,-initiationa,-ofa,-insulina,-injections.a,-Responds,a,-"Ia,-knowa,-thata,-insulina,-woulda,-
helpa,-controla,-mya,-blooda,-sugar.a,-Buta,-aa,-lota,-ofa,-peoplea,-ina,-mya,-familya,-havea,-diabetes,a,-anda,-
,insulina,-madea,-thema,-reallya,-sicka,-ata,-times.a,-Patienta,-isa,-ata,-whicha,-stagea,-ofa,-
change?✅contemplation
24yoa,-Ma,-witha,-2-daya,-historya,-ofa,-ana,-itchya,-rasha,-ona,-hisa,-armsa,-anda,-legs.a,-Returneda,-froma,-
aa,-campinga,-tripa,-ina,-thea,-woodsa,-5a,-daysa,-ago.a,-PEa,-showsa,-edematous,a,-erythematousa,-
rasha,-witha,-lineara,-vesicles.a,-Causea,-isa,-activationa,-ofa,-whicha,-cella,-types?✅Ta,-lymphocytes
70yoa,-Ma,-froma,-chinaa,-witha,-poorlya,-differentiateda,-monoclonala,-carcinomaa,-ofa,-thea,-
nasopharynx.a,-DNAa,-probesa,-ofa,-neoplastica,-cellsa,-area,-mosta,-likelya,-toa,-detecta,-genomea,-ofa,-
whicha,-virus?✅EBV
Epidemiologica,-studya,-ofa,-anilinea,-dye,a,-500a,-workersa,-witha,-bladdera,-cancera,-anda,-200a,-
workersa,-without.a,-Exposeda,-toa,-anilinea,-dyes/Havea,-Bladdera,-cancer:a,-Yes/Yesa,-(250),a,-
Yes/Noa,-(50),a,-No/Yesa,-(250),a,-No/Noa,-(150).a,-Oddsa,-ratio?✅3
24yoa,-Ma,-witha,-hxa,-ofa,-IVDAa,-coulda,-nota,-bea,-aroused.a,-Frienda,-reportsa,-thata,-thea,-patienta,-
injecteda,-himselfa,-witha,-aa,-druga,-6a,-hoursa,-ago.a,-Labsa,-showa,-druga,-concentrationa,-ofa,-0.3.a,-
Assuminga,-first-ordera,-one-compartmenta,-kinetics,a,-hasa,-aa,-half-lifea,-ofa,-2a,-hours,a,-anda,-aa,-
volumea,-ofa,-distributiona,-ofa,-200a,-La,-ina,-thisa,-patient.a,-Whata,-isa,-quantitya,-ofa,-druga,-(ina,-mg)a,-
injected?✅480
Compounda,-isa,-takena,-upa,-bya,-bacteriala,-cells.a,-Noa,-energya,-isa,-necessarya,-fora,-uptake,a,-anda,-
thea,-compounda,-isa,-nota,-concentrateda,-ina,-thea,-cell.a,-Whicha,-describesa,-thisa,-mechanisma,-ofa,-
transport?✅carrier-mediateda,-diffusion
Newborna,-hasa,-malea,-genitala,-ductsa,-buta,-femalea,-externala,-genitalia.a,-Cytogenetica,-
analysisa,-showsa,-aa,-46,XYa,-karyotype,a,-anda,-genetica,-testinga,-showsa,-aa,-mutationa,-ofa,-thea,-
genea,-encodinga,-5alpha-reductase.a,-Ina,-absencea,-ofa,-thisa,-mutation,a,-labiaa,-majoraa,-woulda,-
havea,-been?✅scrotum
Studya,-designeda,-toa,-evaluatea,-thea,-efficacya,-ofa,-coenzymea,-Q10a,-ina,-improvinga,-cardiaca,-
outputa,-ina,-patientsa,-witha,-CHF.a,-Sixtya,-patientsa,-witha,-CHFa,-area,-recruited.a,-Eacha,-assigneda,-
bya,-coina,-tossa,-toa,-onea,-ofa,-twoa,-groups.a,-Design?✅randomizeda,-clinicala,-trial
12yoa,-boya,-immerseda,-upa,-toa,-hisa,-necka,-ina,-60Fa,-watera,-fora,-20a,-minutes.a,-Physiologicala,-
changes?✅Centrala,-blooda,-volumea,-INCREASED,a,-ADHa,-(vasopressin)a,-DECREASED,a,-
Atriala,-Natriuretica,-Peptidea,-INCREASED?a,-Ca,-(block3,a,-q23)
Randomizeda,-controlleda,-studya,-ofa,-2000a,-patientsa,-witha,-insomniaa,-isa,-conducteda,-toa,-
evaluatea,-thea,-efficacya,-ofa,-aa,-newa,-medicationa,-toa,-treata,-thisa,-condition.a,-Tena,-subjectsa,-
froma,-botha,-thea,-controla,-anda,-treatmenta,-groupsa,-doa,-nota,-completea,-thea,-studya,-area,-nota,-
includeda,-ina,-thea,-analysis.a,-Treatmenta,-groupa,-ablea,-toa,-falla,-asleepa,-5a,-minutesa,-fastera,-
thana,-controla,-(p=0.001).a,-Neithera,-groupa,-reporta,-ana,-improvementa,-ina,-qualitya,-ofa,-life.a,-
Concludea,-thata,-newa,-meda,-isa,-efficaciousa,-ina,-treatinga,-insomnia.a,-Typea,-ofa,-
, error?✅Failurea,-toa,-distinguisha,-betweena,-statisticala,-significancea,-anda,-clinicala,-
significance
18moa,-girl.a,-Separationa,-ofa,-thea,-umbilicala,-corda,-wasa,-delayeda,-aftera,-birth.a,-Hasa,-hada,-foura,-
severea,-skina,-infectionsa,-Staphylococcusa,-aureus;a,-Noa,-pusa,-formationa,-ata,-infectiona,-sites.a,-
Persistenta,-leukocytosisa,-ina,-absencea,-ofa,-infection.a,-Mechanismsa,-impaired?✅leukocytea,-
adhesiona,-anda,-transmigration
50yoa,-Ma,-witha,-increasinga,-cougha,-fora,-6a,-montha,-anda,-hemoptysisa,-fora,-1a,-week.a,-Smokeda,-
1a,-packa,-pera,-daya,-fora,-32a,-years.a,-Playsa,-squash,a,-swims.a,-CXRa,-showsa,-aa,-3a,-xa,-4-cma,-hilara,-
mass.a,-Cytologica,-examinationa,-ofa,-sputuma,-showsa,-aa,-non-smalla,-cella,-carcinoma.a,-Tellsa,-
patienta,-hea,-hasa,-lunga,-cancer.a,-Thea,-patienta,-responds,a,-"Howa,-cana,-thisa,-bea,-happeninga,-toa,-
m?a,-Ia,-eata,-righta,-anda,-exercise."a,-Appropriatea,-response?✅"Ita,-musta,-bea,-difficulta,-fora,-youa,-
toa,-accepta,-thisa,-diagnosisa,-whena,-youa,-feela,-healthy."
32yoa,-Ma,-witha,-6-montha,-hxa,-ofa,-lowa,-backa,-paina,-anda,-stiffness,a,-worsea,-ina,-morninga,-anda,-
improvea,-duringa,-thea,-day;a,-thea,-paina,-radiatesa,-toa,-hisa,-buttocksa,-buta,-nota,-downa,-hisa,-legs.a,-
Backa,-stiffnessa,-ifa,-hea,-sitsa,-fora,-prolongeda,-periods.a,-Whicha,-toa,-confirma,-diagnosis?✅X-
raysa,-ofa,-thea,-sacroiliaca,-joints
17yoa,-boya,-witha,-8-kga,-weighta,-gaina,-duringa,-thea,-pasta,-year.a,-Noa,-medicala,-illness.a,-BMIa,-isa,-
32.a,-Hea,-asks,a,-"Doa,-youa,-thinka,-thata,-mya,-weighta,-gaina,-isa,-inheriteda,-froma,-mya,-father?"a,-
Appropriatea,-response?✅"Yes,a,-youra,-weighta,-gaina,-cana,-bea,-causeda,-bya,-genesa,-anda,-
environmenta,-combined."
52yoa,-Ma,-neighborsa,-havea,-reporteda,-thata,-hea,-hasa,-beena,-confuseda,-anda,-nota,-takinga,-carea,-
ofa,-himself.a,-4-moa,-Hxa,-ofa,-diarrhea.a,-PEa,-showsa,-extremea,-musclea,-wasting,a,-stomatitis,a,-
anda,-aa,-diffusea,-rasha,-thata,-isa,-worsea,-ina,-sun-exposeda,-areas.a,-Diagnosis?✅pellagra
80yoa,-Fa,-witha,-suspecteda,-temporala,-arteritisa,-(TA).a,-ESRa,-isa,-100,a,-Pretesta,-probabilitya,-fora,-
TAa,-isa,-50%a,-ina,-thisa,-patient.a,-Ina,-thea,-evaluationa,-ofa,-TA,a,-ESRa,-hasa,-aa,-sensitivitya,-ofa,-99%a,-
anda,-specificitya,-ofa,-60%.a,-Baseda,-ona,-thea,-resultsa,-ofa,-thea,-ESRa,-testing,a,-mosta,-appropriatea,-
nexta,-step?✅Additionala,-testinga,-toa,-confirma,-thea,-diagnosisa,-ofa,-TA
Sequencea,-surroundinga,-thea,-firsta,-twoa,-exonsa,-ofa,-thea,-humana,-beta-globina,-genea,-shown,a,-
witha,-exonsa,-ina,-bold.a,-Translationa,-starta,-codona,-isa,-underlined.a,-Aa,-mutationa,-froma,-G-->Aa,-
ata,-positiona,-355a,-isa,-mosta,-likelya,-toa,-leada,-toa,-beta-thalassemiaa,-bya,-whicha,-
mechanism?✅Disruptiona,-ofa,-normala,-splicinga,-bya,-creationa,-ofa,-aa,-newa,-3'a,-splicea,-site?
42yoa,-Ma,-ina,-EDa,-becausea,-ofa,-aa,-10-daya,-historya,-ofa,-progressivea,-fever,a,-SOB,a,-anda,-
nonproductivea,-cough.a,-20-kga,-weighta,-loss.a,-Immigrateda,-toa,-USAa,-froma,-thea,-Ivorya,-Coasta,-
4a,-yearsa,-ago.a,-Tempa,-38C.a,-Lungsa,-clear,a,-CXra,-showsa,-diffusea,-interstitiala,-infiltrate.a,-
Silvera,-staina,-obtaineda,-viaa,-bronchoscopya,-showsa,-Pneumocystisa,-jirovecia,-(formerlya,-P.a,-
carinii).a,-Higha,-dosea,-prednisonea,-anda,-trimethoprim-sulfamethoxazolea,-isa,-initiated,a,-anda,-
a,- a,- a,- a,- a,-
NBME CBSE (usmle step 1)MEDICAL
ACTUAL EXAM NEWEST VERSION
2024-2025 TESTBANK QUESTIONS
AND CORRECT DETAILEDANSWERS
WITH RATIONALES
|ALREADYGRADED A+
ALREADYGRADED A+ a,-
70yoa,-Ma,-diesa,-ina,-aa,-motora,-vehiclea,-collision.a,-Wasa,-undergoinga,-evaluationa,-fora,-occulta,-
blooda,-ina,-thea,-stool.a,-Photoa,-ofa,-transversea,-colona,-shown.a,-Dx?✅Tubulara,-adenoma
38yoa,-Ma,-witha,-1-weeka,-hxa,-ofa,-watery,a,-itchya,-eyesa,-anda,-aa,-runnya,-nose.a,-Physicala,-showsa,-
inflameda,-nasala,-mucosa.a,-Noa,-congestiona,-ina,-lowera,-lung.a,-
Pharmacotherapy?✅Loratadine
16yoa,-girla,-witha,-3-daya,-hxa,-ofa,-fever,a,-nonproductivea,-cough,a,-anda,-fatigue.a,-Ta,-38.3,a,-Pa,-
88/min,a,-BPa,-102-70.a,-PEa,-showsa,-palea,-conjunctivae.a,-CXRa,-showsa,-bilaterala,-interstitiala,-
infiltrates.a,-Blooda,-spontaenouslya,-agglutinatesa,-whilea,-awaitinga,-transporta,-toa,-thea,-
laboratory.a,-Antibodya,-isotypesa,-causinga,-agglutination?✅IgM
24yoa,-Ma,-witha,-smalla,-tendera,-blistersa,-ona,-hisa,-penisa,-3a,-daysa,-aftera,-unprotecteda,-sex.a,-
Photographa,-shown.a,-Causala,-agent?✅HSV-2
42yoa,-Fa,-witha,-3-yeara,-hxa,-ofa,-ana,-intermittenta,-faciala,-rash,a,-includinga,-thea,-forehead,a,-
eyelids,a,-nose,a,-anda,-cheeks.a,-Rasha,-seemsa,-toa,-bea,-gettinga,-worsea,-sincea,-shea,-moveda,-
froma,-Newa,-Yorka,-toa,-Floridaa,-lasta,-year.a,-Spicya,-foodsa,-precipitatea,-aa,-flushinga,-reactiona,-
thata,-seemsa,-toa,-exacerbatea,-thea,-rash.a,-PEa,-showsa,-erythemaa,-overa,-thea,-nosea,-anda,-
cheeks,a,-witha,-scattereda,-telangiectasiasa,-anda,-aa,-fewa,-papules.a,-Dx?✅Rosacea
53yoa,-Ma,-returneda,-froma,-Africa,a,-hasa,-fever,a,-headache,a,-anda,-abdominala,-discomfort.a,-
Receiveda,-appropriatea,-vaccinationsa,-priora,-toa,-thea,-trip.a,-Ta,-39.4C.a,-Aa,-wright-staineda,-
peripherala,-smeara,-shown.a,-Dx?✅Malaria
68yoa,-Fa,-witha,-T2DMa,-anda,-hypertensiona,-thata,-hasa,-beena,-poorlya,-controlleda,-despitea,-
hydrochlorothiazidea,-treatment.a,-BPa,-150/96,a,-Labsa,-showa,-seruma,-glucosea,-concentrationa,-
,ofa,-130a,-anda,-proteinuria.a,-Ina,-additiona,-toa,-currenta,-Rx,a,-whicha,-isa,-mosta,-appropriatea,-
pharmacotherapy?✅Lisinopril
66yoa,-Ma,-witha,-stagea,-IVa,-colona,-cancera,-witha,-3-daya,-hxa,-ofa,-severea,-diarrheaa,-aftera,-
receivinga,-chemotherapya,-witha,-fluorouracil,a,-leucovorin,a,-anda,-Irinotecan.a,-prescribeda,-
opioida,-antidiarrheala,-agenta,-witha,-noa,-CNSa,-effects.a,-Whicha,-med?✅Loperamide
35yoa,-Ma,-ina,-EDa,-witha,-2-houra,-hxa,-ofa,-severa,-fatiguea,-anda,-dizziness.a,-Hada,-profuse,a,-waterya,-
diarrheaa,-fora,-8a,-hoursa,-despitea,-aa,-lacka,-ofa,-orala,-intake.a,-Recentlya,-returneda,-froma,-aa,-
medicala,-reliefa,-tripa,-toa,-aa,-removea,-villagea,-ina,-Honduras.a,-Ta,-36.7a,-C,a,-Pa,-122/min,a,-BPa,-
90/50.a,-PEa,-showsa,-drya,-skina,-anda,-decreaseda,-capillarya,-refill.a,-Stoola,-fora,-occulta,-blooda,-isa,-
negative;a,-stoola,-isa,-graya,-anda,-turbid.a,-Grama,-staina,-showsa,-gram-negative,a,-comma-
shapeda,-bacteria;a,-noa,-erythrocytesa,-ofa,-leukocytes.a,-MOAa,-ofa,-toxin?✅Activationa,-ofa,-
adenylyla,-cyclase
59yoa,-Fa,-witha,-graduala,-onseta,-ofa,-lacka,-ofa,-musclea,-controla,-ina,-hera,-lefta,-arma,-anda,-leg.a,-Sxa,-1a,-
moa,-agoa,-aftera,-dxa,-witha,-metastatica,-breasta,-cancer.a,-PEa,-showsa,-ataxiaa,-ofa,-lefta,-uppera,-
anda,-lowera,-extremities.a,-Musclea,-strength,a,-DTR,a,-sensation,a,-proprioceptiona,-normal.a,-
Metastatica,-tumora,-ina,-whicha,-location?✅cerebellum
Newborna,-delivereda,-ata,-38a,-weeks'a,-gestationa,-weighsa,-1800a,-g.a,-PEa,-showsa,-petechiala,-
rash,a,-microcephaly,a,-anda,-hepatosplenomegaly.a,-Serologica,-testa,-fora,-CMV:a,-IgGa,-+a,-ina,-
mother,a,-+a,-ina,-newborn;a,-IGMa,--a,-ina,-mother,a,-+a,-ina,-newborn.a,-Explanation?✅Congenitala,-
cytomegalovirusa,-infection
Femalea,-newborna,-isa,-delivereda,-ata,-38a,-weeks'a,-gestation.a,-Apgara,-8a,-anda,-8a,-ata,-1/5a,-min.a,-
PEa,-showsa,-aa,-bulging,a,-fluod0filleda,-massa,-approximatelya,-5a,-cma,-ina,-diametera,-ina,-thea,-
midlinea,-overa,-thea,-lumbosacrala,-region.a,-Noa,-spontaneousa,-movementsa,-ofa,-thea,-lowera,-
extremities.a,-Abnormalitya,-mosta,-likelya,-occurreda,-becausea,-ofa,-abnormala,-developmenta,-
duringa,-whicha,-periodsa,-ofa,-postconceptiona,-(ina,-days)?✅15a,-toa,-40
64yoa,-Ma,-ina,-EDa,-3a,-hoursa,-aftera,-SOBa,-witha,-exertiona,-anda,-extremea,-fatigue.a,-Hasa,-
ischemica,-hearta,-disease.a,-Pa,-125/min,a,-BPa,-105/60.a,-ECGa,-showsa,-atriala,-fibrillation.a,-
Intravenousa,-ibutilidea,-isa,-administered.a,-Tena,-minutesa,-later,a,-ECGa,-showsa,-normala,-sinusa,-
rhythm.a,-Riska,-fora,-whicha,-druga,-effecta,-ina,-thea,-nexta,-6a,-hours?✅torsadesa,-dea,-pointes
65yoa,-Fa,-witha,-20-yeara,-hxa,-ofa,-osteoarthritisa,-ofa,-thea,-handsa,-nowa,-hasa,-paina,-radiatinga,-
downa,-thea,-distala,-anteriora,-thigh,a,-knee,a,-mediala,-leg,a,-anda,-food.a,-Bonya,-outgrowtha,-ofa,-
vertebraea,-compressinga,-onea,-ofa,-thea,-spinala,-nervesa,-isa,-suspected.a,-Nervea,-roota,-ina,-
whicha,-intervertebrala,-foraminaa,-isa,-effected?✅L3a,-toa,-L4
38yoa,-Ma,-witha,-3-yeara,-hxa,-ofa,-T2DM.a,-Takinga,-ana,-orala,-antihyperglycemica,-agent,a,-hea,-hasa,-
trieda,-dieta,-anda,-exercise.a,-BMIa,-32.a,-PEa,-normal.a,-Hba,-A1ca,-isa,-10%.a,-Physiciana,-
recommendsa,-initiationa,-ofa,-insulina,-injections.a,-Responds,a,-"Ia,-knowa,-thata,-insulina,-woulda,-
helpa,-controla,-mya,-blooda,-sugar.a,-Buta,-aa,-lota,-ofa,-peoplea,-ina,-mya,-familya,-havea,-diabetes,a,-anda,-
,insulina,-madea,-thema,-reallya,-sicka,-ata,-times.a,-Patienta,-isa,-ata,-whicha,-stagea,-ofa,-
change?✅contemplation
24yoa,-Ma,-witha,-2-daya,-historya,-ofa,-ana,-itchya,-rasha,-ona,-hisa,-armsa,-anda,-legs.a,-Returneda,-froma,-
aa,-campinga,-tripa,-ina,-thea,-woodsa,-5a,-daysa,-ago.a,-PEa,-showsa,-edematous,a,-erythematousa,-
rasha,-witha,-lineara,-vesicles.a,-Causea,-isa,-activationa,-ofa,-whicha,-cella,-types?✅Ta,-lymphocytes
70yoa,-Ma,-froma,-chinaa,-witha,-poorlya,-differentiateda,-monoclonala,-carcinomaa,-ofa,-thea,-
nasopharynx.a,-DNAa,-probesa,-ofa,-neoplastica,-cellsa,-area,-mosta,-likelya,-toa,-detecta,-genomea,-ofa,-
whicha,-virus?✅EBV
Epidemiologica,-studya,-ofa,-anilinea,-dye,a,-500a,-workersa,-witha,-bladdera,-cancera,-anda,-200a,-
workersa,-without.a,-Exposeda,-toa,-anilinea,-dyes/Havea,-Bladdera,-cancer:a,-Yes/Yesa,-(250),a,-
Yes/Noa,-(50),a,-No/Yesa,-(250),a,-No/Noa,-(150).a,-Oddsa,-ratio?✅3
24yoa,-Ma,-witha,-hxa,-ofa,-IVDAa,-coulda,-nota,-bea,-aroused.a,-Frienda,-reportsa,-thata,-thea,-patienta,-
injecteda,-himselfa,-witha,-aa,-druga,-6a,-hoursa,-ago.a,-Labsa,-showa,-druga,-concentrationa,-ofa,-0.3.a,-
Assuminga,-first-ordera,-one-compartmenta,-kinetics,a,-hasa,-aa,-half-lifea,-ofa,-2a,-hours,a,-anda,-aa,-
volumea,-ofa,-distributiona,-ofa,-200a,-La,-ina,-thisa,-patient.a,-Whata,-isa,-quantitya,-ofa,-druga,-(ina,-mg)a,-
injected?✅480
Compounda,-isa,-takena,-upa,-bya,-bacteriala,-cells.a,-Noa,-energya,-isa,-necessarya,-fora,-uptake,a,-anda,-
thea,-compounda,-isa,-nota,-concentrateda,-ina,-thea,-cell.a,-Whicha,-describesa,-thisa,-mechanisma,-ofa,-
transport?✅carrier-mediateda,-diffusion
Newborna,-hasa,-malea,-genitala,-ductsa,-buta,-femalea,-externala,-genitalia.a,-Cytogenetica,-
analysisa,-showsa,-aa,-46,XYa,-karyotype,a,-anda,-genetica,-testinga,-showsa,-aa,-mutationa,-ofa,-thea,-
genea,-encodinga,-5alpha-reductase.a,-Ina,-absencea,-ofa,-thisa,-mutation,a,-labiaa,-majoraa,-woulda,-
havea,-been?✅scrotum
Studya,-designeda,-toa,-evaluatea,-thea,-efficacya,-ofa,-coenzymea,-Q10a,-ina,-improvinga,-cardiaca,-
outputa,-ina,-patientsa,-witha,-CHF.a,-Sixtya,-patientsa,-witha,-CHFa,-area,-recruited.a,-Eacha,-assigneda,-
bya,-coina,-tossa,-toa,-onea,-ofa,-twoa,-groups.a,-Design?✅randomizeda,-clinicala,-trial
12yoa,-boya,-immerseda,-upa,-toa,-hisa,-necka,-ina,-60Fa,-watera,-fora,-20a,-minutes.a,-Physiologicala,-
changes?✅Centrala,-blooda,-volumea,-INCREASED,a,-ADHa,-(vasopressin)a,-DECREASED,a,-
Atriala,-Natriuretica,-Peptidea,-INCREASED?a,-Ca,-(block3,a,-q23)
Randomizeda,-controlleda,-studya,-ofa,-2000a,-patientsa,-witha,-insomniaa,-isa,-conducteda,-toa,-
evaluatea,-thea,-efficacya,-ofa,-aa,-newa,-medicationa,-toa,-treata,-thisa,-condition.a,-Tena,-subjectsa,-
froma,-botha,-thea,-controla,-anda,-treatmenta,-groupsa,-doa,-nota,-completea,-thea,-studya,-area,-nota,-
includeda,-ina,-thea,-analysis.a,-Treatmenta,-groupa,-ablea,-toa,-falla,-asleepa,-5a,-minutesa,-fastera,-
thana,-controla,-(p=0.001).a,-Neithera,-groupa,-reporta,-ana,-improvementa,-ina,-qualitya,-ofa,-life.a,-
Concludea,-thata,-newa,-meda,-isa,-efficaciousa,-ina,-treatinga,-insomnia.a,-Typea,-ofa,-
, error?✅Failurea,-toa,-distinguisha,-betweena,-statisticala,-significancea,-anda,-clinicala,-
significance
18moa,-girl.a,-Separationa,-ofa,-thea,-umbilicala,-corda,-wasa,-delayeda,-aftera,-birth.a,-Hasa,-hada,-foura,-
severea,-skina,-infectionsa,-Staphylococcusa,-aureus;a,-Noa,-pusa,-formationa,-ata,-infectiona,-sites.a,-
Persistenta,-leukocytosisa,-ina,-absencea,-ofa,-infection.a,-Mechanismsa,-impaired?✅leukocytea,-
adhesiona,-anda,-transmigration
50yoa,-Ma,-witha,-increasinga,-cougha,-fora,-6a,-montha,-anda,-hemoptysisa,-fora,-1a,-week.a,-Smokeda,-
1a,-packa,-pera,-daya,-fora,-32a,-years.a,-Playsa,-squash,a,-swims.a,-CXRa,-showsa,-aa,-3a,-xa,-4-cma,-hilara,-
mass.a,-Cytologica,-examinationa,-ofa,-sputuma,-showsa,-aa,-non-smalla,-cella,-carcinoma.a,-Tellsa,-
patienta,-hea,-hasa,-lunga,-cancer.a,-Thea,-patienta,-responds,a,-"Howa,-cana,-thisa,-bea,-happeninga,-toa,-
m?a,-Ia,-eata,-righta,-anda,-exercise."a,-Appropriatea,-response?✅"Ita,-musta,-bea,-difficulta,-fora,-youa,-
toa,-accepta,-thisa,-diagnosisa,-whena,-youa,-feela,-healthy."
32yoa,-Ma,-witha,-6-montha,-hxa,-ofa,-lowa,-backa,-paina,-anda,-stiffness,a,-worsea,-ina,-morninga,-anda,-
improvea,-duringa,-thea,-day;a,-thea,-paina,-radiatesa,-toa,-hisa,-buttocksa,-buta,-nota,-downa,-hisa,-legs.a,-
Backa,-stiffnessa,-ifa,-hea,-sitsa,-fora,-prolongeda,-periods.a,-Whicha,-toa,-confirma,-diagnosis?✅X-
raysa,-ofa,-thea,-sacroiliaca,-joints
17yoa,-boya,-witha,-8-kga,-weighta,-gaina,-duringa,-thea,-pasta,-year.a,-Noa,-medicala,-illness.a,-BMIa,-isa,-
32.a,-Hea,-asks,a,-"Doa,-youa,-thinka,-thata,-mya,-weighta,-gaina,-isa,-inheriteda,-froma,-mya,-father?"a,-
Appropriatea,-response?✅"Yes,a,-youra,-weighta,-gaina,-cana,-bea,-causeda,-bya,-genesa,-anda,-
environmenta,-combined."
52yoa,-Ma,-neighborsa,-havea,-reporteda,-thata,-hea,-hasa,-beena,-confuseda,-anda,-nota,-takinga,-carea,-
ofa,-himself.a,-4-moa,-Hxa,-ofa,-diarrhea.a,-PEa,-showsa,-extremea,-musclea,-wasting,a,-stomatitis,a,-
anda,-aa,-diffusea,-rasha,-thata,-isa,-worsea,-ina,-sun-exposeda,-areas.a,-Diagnosis?✅pellagra
80yoa,-Fa,-witha,-suspecteda,-temporala,-arteritisa,-(TA).a,-ESRa,-isa,-100,a,-Pretesta,-probabilitya,-fora,-
TAa,-isa,-50%a,-ina,-thisa,-patient.a,-Ina,-thea,-evaluationa,-ofa,-TA,a,-ESRa,-hasa,-aa,-sensitivitya,-ofa,-99%a,-
anda,-specificitya,-ofa,-60%.a,-Baseda,-ona,-thea,-resultsa,-ofa,-thea,-ESRa,-testing,a,-mosta,-appropriatea,-
nexta,-step?✅Additionala,-testinga,-toa,-confirma,-thea,-diagnosisa,-ofa,-TA
Sequencea,-surroundinga,-thea,-firsta,-twoa,-exonsa,-ofa,-thea,-humana,-beta-globina,-genea,-shown,a,-
witha,-exonsa,-ina,-bold.a,-Translationa,-starta,-codona,-isa,-underlined.a,-Aa,-mutationa,-froma,-G-->Aa,-
ata,-positiona,-355a,-isa,-mosta,-likelya,-toa,-leada,-toa,-beta-thalassemiaa,-bya,-whicha,-
mechanism?✅Disruptiona,-ofa,-normala,-splicinga,-bya,-creationa,-ofa,-aa,-newa,-3'a,-splicea,-site?
42yoa,-Ma,-ina,-EDa,-becausea,-ofa,-aa,-10-daya,-historya,-ofa,-progressivea,-fever,a,-SOB,a,-anda,-
nonproductivea,-cough.a,-20-kga,-weighta,-loss.a,-Immigrateda,-toa,-USAa,-froma,-thea,-Ivorya,-Coasta,-
4a,-yearsa,-ago.a,-Tempa,-38C.a,-Lungsa,-clear,a,-CXra,-showsa,-diffusea,-interstitiala,-infiltrate.a,-
Silvera,-staina,-obtaineda,-viaa,-bronchoscopya,-showsa,-Pneumocystisa,-jirovecia,-(formerlya,-P.a,-
carinii).a,-Higha,-dosea,-prednisonea,-anda,-trimethoprim-sulfamethoxazolea,-isa,-initiated,a,-anda,-
