Chapter 39 Acid-Controlling Drugs
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Antacids that contain aluminum salts may result in which adverse effect?
a. Diarrhea
b. Constipation
c. Intestinal flatulence d.
Abdominal cramping
ANS B
Aluminum-based antacids have a constipating effect and an acid-neutralizing capacity. DIF
Cognitive Level Knowledge
2. Antacids containing magnesium should be used cautiously in patients with which condition?
a. Peptic ulcer disease
b. Renal failure c. Hypertension d. Heart failure
ANS B
The failing kidney cannot excrete the extra magnesium, and accumulation may occur.
DIF Cognitive Level Application
3. H2 antagonists, such as cimetidine, may inhibit the absorption of drugs that require an acidic
gastrointestinal environment. Which drug requires an acidic gastrointestinal environment?
a. Nonsteroidal anti-inflammatory drugs b.
Ranitidine (Zantac®)
c. Tetracycline
d. Ketoconazole
ANS D
, Ketoconazole requires an acidic gastrointestinal environment for gastric absorption.
DIF Cognitive Level Comprehension
4. A patient has been taking cimetidine for hyperacidity but says that the medication
has not been effective. What is the patient doing that may be influencing the
effectiveness of this drug?
a. The patient is taking the cimetidine with meals.
b. The patient is smoking two packs of cigarettes a day.
c. The patient is avoiding caffeine, alcohol, and harsh spices.
d. The patient is taking an antacid 1 hour before or after taking the cimetidine dose.
ANS B
Smoking may impair the absorption of H2 antagonists. Taking cimetidine with meals; avoiding caffeine,
alcohol, and harsh spices;
and taking an antacid 1 hour before or after the cimetidine dose are proper interventions for this
medication.
DIF Cognitive Level Analysis
5. A patient is taking omeprazole (Losec®) for the treatment of gastroesophageal reflux disease. What
important information should the nurse give the patient about this medication?
a. The medication is taken once a day after meals.
b. The patient will be taking this medication for long-term therapy.
c. The medication may be dissolved in a liquid for better absorption.
d. The entire capsule should be taken whole and not crushed, chewed, or opened.
ANS D
An entire omeprazole capsule should be taken whole and not crushed, chewed, or opened. Omeprazole
is intended for short-term therapy and should be taken before meals.
DIF Cognitive Level Application
Sealock Lilley’s Pharmacology for Canadian Health Care Practice
MULTIPLE CHOICE
1. Antacids that contain aluminum salts may result in which adverse effect?
a. Diarrhea
b. Constipation
c. Intestinal flatulence d.
Abdominal cramping
ANS B
Aluminum-based antacids have a constipating effect and an acid-neutralizing capacity. DIF
Cognitive Level Knowledge
2. Antacids containing magnesium should be used cautiously in patients with which condition?
a. Peptic ulcer disease
b. Renal failure c. Hypertension d. Heart failure
ANS B
The failing kidney cannot excrete the extra magnesium, and accumulation may occur.
DIF Cognitive Level Application
3. H2 antagonists, such as cimetidine, may inhibit the absorption of drugs that require an acidic
gastrointestinal environment. Which drug requires an acidic gastrointestinal environment?
a. Nonsteroidal anti-inflammatory drugs b.
Ranitidine (Zantac®)
c. Tetracycline
d. Ketoconazole
ANS D
, Ketoconazole requires an acidic gastrointestinal environment for gastric absorption.
DIF Cognitive Level Comprehension
4. A patient has been taking cimetidine for hyperacidity but says that the medication
has not been effective. What is the patient doing that may be influencing the
effectiveness of this drug?
a. The patient is taking the cimetidine with meals.
b. The patient is smoking two packs of cigarettes a day.
c. The patient is avoiding caffeine, alcohol, and harsh spices.
d. The patient is taking an antacid 1 hour before or after taking the cimetidine dose.
ANS B
Smoking may impair the absorption of H2 antagonists. Taking cimetidine with meals; avoiding caffeine,
alcohol, and harsh spices;
and taking an antacid 1 hour before or after the cimetidine dose are proper interventions for this
medication.
DIF Cognitive Level Analysis
5. A patient is taking omeprazole (Losec®) for the treatment of gastroesophageal reflux disease. What
important information should the nurse give the patient about this medication?
a. The medication is taken once a day after meals.
b. The patient will be taking this medication for long-term therapy.
c. The medication may be dissolved in a liquid for better absorption.
d. The entire capsule should be taken whole and not crushed, chewed, or opened.
ANS D
An entire omeprazole capsule should be taken whole and not crushed, chewed, or opened. Omeprazole
is intended for short-term therapy and should be taken before meals.
DIF Cognitive Level Application
