WGU Pathophysiology Final Exam QUESTIONS
AND ANSwers 2025\2026 UPDATE
1. While performing the genital assessment of a male client, a nurse observes that the client has
curvature of the penis. Which condition does the nurse suspect in the client?-
ANS>>Peyronie's disease
2. A client tells a nurse, "My erections lasts for several hours and are painful. "Which
medication found in the client's prescription is responsible?-ANS>>Sildenafil
3. A nurse observes that a newborn has an abnormally positioned urethral orifice of the penis.
Which disorder will the nurse suspect in the newborn?-ANS>>Hypospadias
4. Which physical finding in a client will lead a nurse to suspect paraphimosis?-
ANS>>Permanent retracted position of the foreskin behind the penis
5. A registered nurse is teaching about the medications for benign prostatic hyperplasia (BPH)
to a group of student nurses. Which statement of a student nurse indicates the need for
further teaching?-ANS>>"Alpha-blockers REDUCE the size of the prostate."
6. Which hormone stimulates Sertoli cells to synthesize spermatozoa?-ANS>>Follicle-
stimulating hormone (FSH)
7. While assessing a male client for reproductive disorders, the primary health-care provider
wants to understand whether the client has prostate cancer or benign prostatic hyperplasia
(BPH). Which diagnostic test will the nurse expect in this case?-ANS>>Both A and B
8. (Ultrasound
9. Urine flow studies)
10. While assessing a male client, a nurse finds erythema, swelling, and tenderness of the
scrotum. The client also reports pain in the scrotum. Which disorder does the nurse suspect
in the client?-ANS>>Testicular torsion
,12. Alpha-blockers help to relax the smooth muscles of the prostate but do not aid in
reducing the size of the prostate.
13. While assessing a male client, a nurse observes swelling in the scrotum due to the
collection of serous fluid. Which condition does the nurse suspect in the client?-
ANS>>HYDROcele
14. Which disorder can occur due to HIV?-ANS>>Testicular cancer
15. Which artery provides engorgement of the glans during erection?-ANS>>Dorsal
16. After examining an elderly client's penis, a nurse finds the presence of scar tissue in
the corpora cavernosum. On further assessment, the nurse confirms Peyronie's disease in
the client. Which finding supports the nurse's confirmation?-ANS>>Presence of a curved
penis
17. A nurse teaches intervention to a client for healthy spermatogenesis. During a follow-
up visit, the nurse finds that the client has risk for diminished sperm production. Which
statement of the client supports the nurse's conclusion?-ANS>>"I should take a hot bath
regularly."
18. During an assessment, a nurse observes the signs of diminished secondary sexual
characteristics in an adult male client. What should be the appropriate nursing action?-
ANS>>Measure the morning serum testosterone levels.
19. Which hormone stimulates the Leydig cells of the testes to secrete testosterone?-
ANS>>Luteinizing hormone
20. Which cells secrete inhibin hormone?-ANS>>Sertoli cells
21. Which condition can cause ischemia of the testicle?-ANS>>Testicular torsion
22. While assessing a male client, a nurse observes that the client has a small penis, long
legs, short trunk, enlarged breast tissues, small testicles, and sexual dysfunction. What
reason does the nurse suspect from these findings?-ANS>>Presence of an extra X
chromosome
23. Which gland secretes a lubricating fluid that coats the urethra during sexual arousal?-
ANS>>Bulbourethral gland
, 26. Homeostasis Maintenance-ANS>>Hormones regulate physiological parameters for
internal balance
27. Growth and Development-ANS>>Hormones influence growth, muscle development, and
maturation
28. Stress Response-ANS>>Endocrine system releases cortisol to adapt to stressors
29. Autoimmune Diseases-ANS>>Immune system attacks endocrine glands, causing
disorders
30. Neoplastic Growth-ANS>>Tumors in glands disrupt hormone production and functions
31. Pituitary Gland Disorders-ANS>>Conditions affecting pituitary hormone secretion
levels
32. Hypopituitarism-ANS>>Underactivity of pituitary gland causing hormone deficiencies
33. Hyperpituitarism-ANS>>Overactivity of pituitary gland leading to hormone excess
34. SIADH-ANS>>Excessive antidiuretic hormone secretion causing water retention
35. Thyroid Disorders-ANS>>Conditions affecting thyroid hormone production and
function
36. Graves' Disease-ANS>>Autoimmune hyperthyroidism with goiter and eye involvement
37. Hypothyroidism-ANS>>Underactive thyroid gland causing hormone deficiency
symptoms
38. Thyrotoxicosis-ANS>>Excessive thyroid hormone activity in the body
39. Adrenal Gland Disorders-ANS>>Conditions affecting adrenal hormone production and
function
40. Cushing's Disease-ANS>>Hypercortisolism due to excessive ACTH production
41. Addison's Disease-ANS>>Adrenal insufficiency from autoimmune adrenal destruction
AND ANSwers 2025\2026 UPDATE
1. While performing the genital assessment of a male client, a nurse observes that the client has
curvature of the penis. Which condition does the nurse suspect in the client?-
ANS>>Peyronie's disease
2. A client tells a nurse, "My erections lasts for several hours and are painful. "Which
medication found in the client's prescription is responsible?-ANS>>Sildenafil
3. A nurse observes that a newborn has an abnormally positioned urethral orifice of the penis.
Which disorder will the nurse suspect in the newborn?-ANS>>Hypospadias
4. Which physical finding in a client will lead a nurse to suspect paraphimosis?-
ANS>>Permanent retracted position of the foreskin behind the penis
5. A registered nurse is teaching about the medications for benign prostatic hyperplasia (BPH)
to a group of student nurses. Which statement of a student nurse indicates the need for
further teaching?-ANS>>"Alpha-blockers REDUCE the size of the prostate."
6. Which hormone stimulates Sertoli cells to synthesize spermatozoa?-ANS>>Follicle-
stimulating hormone (FSH)
7. While assessing a male client for reproductive disorders, the primary health-care provider
wants to understand whether the client has prostate cancer or benign prostatic hyperplasia
(BPH). Which diagnostic test will the nurse expect in this case?-ANS>>Both A and B
8. (Ultrasound
9. Urine flow studies)
10. While assessing a male client, a nurse finds erythema, swelling, and tenderness of the
scrotum. The client also reports pain in the scrotum. Which disorder does the nurse suspect
in the client?-ANS>>Testicular torsion
,12. Alpha-blockers help to relax the smooth muscles of the prostate but do not aid in
reducing the size of the prostate.
13. While assessing a male client, a nurse observes swelling in the scrotum due to the
collection of serous fluid. Which condition does the nurse suspect in the client?-
ANS>>HYDROcele
14. Which disorder can occur due to HIV?-ANS>>Testicular cancer
15. Which artery provides engorgement of the glans during erection?-ANS>>Dorsal
16. After examining an elderly client's penis, a nurse finds the presence of scar tissue in
the corpora cavernosum. On further assessment, the nurse confirms Peyronie's disease in
the client. Which finding supports the nurse's confirmation?-ANS>>Presence of a curved
penis
17. A nurse teaches intervention to a client for healthy spermatogenesis. During a follow-
up visit, the nurse finds that the client has risk for diminished sperm production. Which
statement of the client supports the nurse's conclusion?-ANS>>"I should take a hot bath
regularly."
18. During an assessment, a nurse observes the signs of diminished secondary sexual
characteristics in an adult male client. What should be the appropriate nursing action?-
ANS>>Measure the morning serum testosterone levels.
19. Which hormone stimulates the Leydig cells of the testes to secrete testosterone?-
ANS>>Luteinizing hormone
20. Which cells secrete inhibin hormone?-ANS>>Sertoli cells
21. Which condition can cause ischemia of the testicle?-ANS>>Testicular torsion
22. While assessing a male client, a nurse observes that the client has a small penis, long
legs, short trunk, enlarged breast tissues, small testicles, and sexual dysfunction. What
reason does the nurse suspect from these findings?-ANS>>Presence of an extra X
chromosome
23. Which gland secretes a lubricating fluid that coats the urethra during sexual arousal?-
ANS>>Bulbourethral gland
, 26. Homeostasis Maintenance-ANS>>Hormones regulate physiological parameters for
internal balance
27. Growth and Development-ANS>>Hormones influence growth, muscle development, and
maturation
28. Stress Response-ANS>>Endocrine system releases cortisol to adapt to stressors
29. Autoimmune Diseases-ANS>>Immune system attacks endocrine glands, causing
disorders
30. Neoplastic Growth-ANS>>Tumors in glands disrupt hormone production and functions
31. Pituitary Gland Disorders-ANS>>Conditions affecting pituitary hormone secretion
levels
32. Hypopituitarism-ANS>>Underactivity of pituitary gland causing hormone deficiencies
33. Hyperpituitarism-ANS>>Overactivity of pituitary gland leading to hormone excess
34. SIADH-ANS>>Excessive antidiuretic hormone secretion causing water retention
35. Thyroid Disorders-ANS>>Conditions affecting thyroid hormone production and
function
36. Graves' Disease-ANS>>Autoimmune hyperthyroidism with goiter and eye involvement
37. Hypothyroidism-ANS>>Underactive thyroid gland causing hormone deficiency
symptoms
38. Thyrotoxicosis-ANS>>Excessive thyroid hormone activity in the body
39. Adrenal Gland Disorders-ANS>>Conditions affecting adrenal hormone production and
function
40. Cushing's Disease-ANS>>Hypercortisolism due to excessive ACTH production
41. Addison's Disease-ANS>>Adrenal insufficiency from autoimmune adrenal destruction
