COMLEX Level 1 Exam 2026 Questions
and Answers 100% Pass Guaranteed
cysteine stone - Correct answer-- *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Ornithine, Lysine, Arginine
- Does NOT respond to shock wave therapy
angiodysplasia - Correct answer-most common cause of lower GI bleeding in pt's
>60
superior mesenteric artery - Correct answer-supplies the lower portion of the
duodenum, jejunum, ileum, cecum, ascending colon, and transverse colon to the
splenic flexure
pancreatic cancer - Correct answer--usually arises in the *head* of the pancreas
-is associated with *jaundice and pain* due to obstruction of the common bile duct
- it is the *4th* most common cause of cancer
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,-has a very poor prognosis
1. Calcium channel blockers--> specifically smooth muscle antagonists--> SM
dilation
2. Alpha adrenergic receptor blockers --> cause dilation of vessels instead of
constriction
3. Beta 2 agonists: causes dilation of smooth muscle vessels - Correct answer-
Patients with GERD normally have a dysfunction with LES sphincter tone that
allows acid to reflux into the esophagus, thus drugs that affect sphincter tone would
make GERD worse. What are the name of three drug categories that do this?
celiac disease - Correct answer-malabsorption syndrome caused by an immune
reaction to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa and causes steatorrhea,
diarrhea, bloating and abdominal pain
-*also associated with other autoimmune disorders like hashimotos thyroiditis*
make NPO, Place on an NG tube and suction obstruction out--> this will usually
resolve obstruction - Correct answer-after a patient comes to the ER with sudden
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,onset of pain and abdominal distention W/O peritoneal signs and after x-ray you
diagnose her with a small bowel obstruction. What do you do next?
Low total calcium due to low albumin levels from cirrhosis (95% of Ca2+ is bound
to albumin) and normal ionized Ca2+ because PTH regulates free ionized Ca2+
independently--> that is why there are no signs go hypocalcemia - Correct answer-
In a patient with liver cirrhosis what calcium levels would you expect to see?
Would there be signs of hypocalcemia--> tetany, paresthesias, abdominal cramps?
T5-T11 - Correct answer-where would you find a viserosomatic reflex resulting in
placatory changes of the pancreas?
Deferoxamine (Desferal) - Correct answer-iron chelating agent used in the
treatment of iron intoxication
short leg syndrome - Correct answer-when a patient presents with a flexible
scoliotic curve it is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which are in the temporal
region - Correct answer-Infarct to what trunk of the Left MCA results in
Wernicke's aphasia?
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, Superior division--> encompasses brooks area, frontal eye field, primary motor
cortex and primary somatosensory cortex - Correct answer-Infarct to what trunk of
the Left MCA results in Broca's aphasia?
Osteosarcoma - Correct answer-bone tumor that is present in young adult males
that involves the metaphysis of the long bones
Ewing's sarcoma t(11;22) - Correct answer-bone tumor that is present in young
adult males that involves the *diaphysis(mid-shaft)* of the long bones.
fibrosarcoma - Correct answer-malignant fibroblasts within a collagenous matrix
chondrosarcoma - Correct answer-osseous sarcomas that affect older patients and
has a predilection for flat bones in the *shoulders and pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase - Correct answer-PKU
presents as failure to thrive, mental retardation, gapped teeth, etc. What is the
amino acid that needs to be supplemented due to a defect in what enzyme?
Rib 2 - Correct answer-where does the posterior scalene attach to?
Paclitaxel - Correct answer-used in the treatment of breast and ovarian cancer
MOA: hyper stabilization of polymerized microtubules--> prevents the breakdown
of the mitotic spindle
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and Answers 100% Pass Guaranteed
cysteine stone - Correct answer-- *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Ornithine, Lysine, Arginine
- Does NOT respond to shock wave therapy
angiodysplasia - Correct answer-most common cause of lower GI bleeding in pt's
>60
superior mesenteric artery - Correct answer-supplies the lower portion of the
duodenum, jejunum, ileum, cecum, ascending colon, and transverse colon to the
splenic flexure
pancreatic cancer - Correct answer--usually arises in the *head* of the pancreas
-is associated with *jaundice and pain* due to obstruction of the common bile duct
- it is the *4th* most common cause of cancer
©COPYRIGHT 2025, ALL RIGHTS RESERVE 1
,-has a very poor prognosis
1. Calcium channel blockers--> specifically smooth muscle antagonists--> SM
dilation
2. Alpha adrenergic receptor blockers --> cause dilation of vessels instead of
constriction
3. Beta 2 agonists: causes dilation of smooth muscle vessels - Correct answer-
Patients with GERD normally have a dysfunction with LES sphincter tone that
allows acid to reflux into the esophagus, thus drugs that affect sphincter tone would
make GERD worse. What are the name of three drug categories that do this?
celiac disease - Correct answer-malabsorption syndrome caused by an immune
reaction to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa and causes steatorrhea,
diarrhea, bloating and abdominal pain
-*also associated with other autoimmune disorders like hashimotos thyroiditis*
make NPO, Place on an NG tube and suction obstruction out--> this will usually
resolve obstruction - Correct answer-after a patient comes to the ER with sudden
©COPYRIGHT 2025, ALL RIGHTS RESERVE 2
,onset of pain and abdominal distention W/O peritoneal signs and after x-ray you
diagnose her with a small bowel obstruction. What do you do next?
Low total calcium due to low albumin levels from cirrhosis (95% of Ca2+ is bound
to albumin) and normal ionized Ca2+ because PTH regulates free ionized Ca2+
independently--> that is why there are no signs go hypocalcemia - Correct answer-
In a patient with liver cirrhosis what calcium levels would you expect to see?
Would there be signs of hypocalcemia--> tetany, paresthesias, abdominal cramps?
T5-T11 - Correct answer-where would you find a viserosomatic reflex resulting in
placatory changes of the pancreas?
Deferoxamine (Desferal) - Correct answer-iron chelating agent used in the
treatment of iron intoxication
short leg syndrome - Correct answer-when a patient presents with a flexible
scoliotic curve it is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which are in the temporal
region - Correct answer-Infarct to what trunk of the Left MCA results in
Wernicke's aphasia?
©COPYRIGHT 2025, ALL RIGHTS RESERVE 3
, Superior division--> encompasses brooks area, frontal eye field, primary motor
cortex and primary somatosensory cortex - Correct answer-Infarct to what trunk of
the Left MCA results in Broca's aphasia?
Osteosarcoma - Correct answer-bone tumor that is present in young adult males
that involves the metaphysis of the long bones
Ewing's sarcoma t(11;22) - Correct answer-bone tumor that is present in young
adult males that involves the *diaphysis(mid-shaft)* of the long bones.
fibrosarcoma - Correct answer-malignant fibroblasts within a collagenous matrix
chondrosarcoma - Correct answer-osseous sarcomas that affect older patients and
has a predilection for flat bones in the *shoulders and pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase - Correct answer-PKU
presents as failure to thrive, mental retardation, gapped teeth, etc. What is the
amino acid that needs to be supplemented due to a defect in what enzyme?
Rib 2 - Correct answer-where does the posterior scalene attach to?
Paclitaxel - Correct answer-used in the treatment of breast and ovarian cancer
MOA: hyper stabilization of polymerized microtubules--> prevents the breakdown
of the mitotic spindle
©COPYRIGHT 2025, ALL RIGHTS RESERVE 4
