COMSAE 111 || 2025/2026 COMPLETE QUESTIONS
WITH VERIFIED CORRECT ANSWERS
100% GUARANTEED SUCCESS <LATEST VERSION>
Question 1
A 64-year-old man presents with chest pain that worsens with exertion and improves with rest.
ECG shows ST-segment depression in leads II, III, and aVF during exercise testing. Which of the
following is the most appropriate initial pharmacologic therapy?
a) Nitroglycerin
b) Aspirin
c) Clopidogrel
d) Warfarin
Answer: b) Aspirin
Aspirin is the first-line antiplatelet therapy in stable angina, reducing thrombus formation and
lowering mortality risk.
Question 2
,A 22-year-old woman presents with abdominal pain and watery diarrhea after recent antibiotic
use. Stool toxin assay is positive. Which of the following is the best treatment?
a) Ciprofloxacin
b) Vancomycin (oral)
c) Metronidazole IV
d) Amoxicillin
Answer: b) Vancomycin (oral)
Oral vancomycin is first-line for C. difficile infection. IV vancomycin is ineffective in colitis as it
doesn’t reach the lumen.
Question 3
A 7-year-old boy presents with a swollen knee, fever, and inability to bear weight. Aspiration
reveals turbid synovial fluid with >50,000 WBCs. Which is the next best step?
a) IV vancomycin
b) Intra-articular steroids
c) Oral amoxicillin
d) Arthroscopic lavage
Answer: d) Arthroscopic lavage
Septic arthritis requires urgent surgical drainage and IV antibiotics to prevent joint destruction.
, Question 4
A 31-year-old woman with systemic lupus erythematosus presents with shortness of breath.
Echocardiography shows a pericardial effusion without tamponade. What is the best
management?
a) Immediate pericardiocentesis
b) IV fluids and pressors
c) NSAIDs and colchicine
d) High-dose corticosteroids
Answer: d) High-dose corticosteroids
Pericarditis due to SLE responds best to corticosteroids, unlike viral pericarditis which uses
NSAIDs/colchicine.
Question 5
A newborn develops cyanosis that worsens with crying and improves when squatting. Chest X-
ray shows a boot-shaped heart. Which is the most likely diagnosis?
a) Tetralogy of Fallot
b) Transposition of the great vessels
c) Tricuspid atresia
d) Total anomalous pulmonary venous return
WITH VERIFIED CORRECT ANSWERS
100% GUARANTEED SUCCESS <LATEST VERSION>
Question 1
A 64-year-old man presents with chest pain that worsens with exertion and improves with rest.
ECG shows ST-segment depression in leads II, III, and aVF during exercise testing. Which of the
following is the most appropriate initial pharmacologic therapy?
a) Nitroglycerin
b) Aspirin
c) Clopidogrel
d) Warfarin
Answer: b) Aspirin
Aspirin is the first-line antiplatelet therapy in stable angina, reducing thrombus formation and
lowering mortality risk.
Question 2
,A 22-year-old woman presents with abdominal pain and watery diarrhea after recent antibiotic
use. Stool toxin assay is positive. Which of the following is the best treatment?
a) Ciprofloxacin
b) Vancomycin (oral)
c) Metronidazole IV
d) Amoxicillin
Answer: b) Vancomycin (oral)
Oral vancomycin is first-line for C. difficile infection. IV vancomycin is ineffective in colitis as it
doesn’t reach the lumen.
Question 3
A 7-year-old boy presents with a swollen knee, fever, and inability to bear weight. Aspiration
reveals turbid synovial fluid with >50,000 WBCs. Which is the next best step?
a) IV vancomycin
b) Intra-articular steroids
c) Oral amoxicillin
d) Arthroscopic lavage
Answer: d) Arthroscopic lavage
Septic arthritis requires urgent surgical drainage and IV antibiotics to prevent joint destruction.
, Question 4
A 31-year-old woman with systemic lupus erythematosus presents with shortness of breath.
Echocardiography shows a pericardial effusion without tamponade. What is the best
management?
a) Immediate pericardiocentesis
b) IV fluids and pressors
c) NSAIDs and colchicine
d) High-dose corticosteroids
Answer: d) High-dose corticosteroids
Pericarditis due to SLE responds best to corticosteroids, unlike viral pericarditis which uses
NSAIDs/colchicine.
Question 5
A newborn develops cyanosis that worsens with crying and improves when squatting. Chest X-
ray shows a boot-shaped heart. Which is the most likely diagnosis?
a) Tetralogy of Fallot
b) Transposition of the great vessels
c) Tricuspid atresia
d) Total anomalous pulmonary venous return
