NBME SAMPLE QUESTIONS
AND ANSWERS
1. RSV is an RNA virus that enters the cell via a fusion protein: (which is the
target of the prophylactic monoclonal antibody drug Palivizumab)
2. Gram-positive rods in a diabetic foot wound (or a World War I soldier fight-
ing in a trench) means: means Clostridium perfringens (the causative organism
of gas gangrene). Crepitus means gas in the tissues, which is produced as a
byproduct of its highly virulent alpha toxin
3. Crepitus: means gas in the tissues, which is produced as a byproduct of its
highly virulent alpha toxin
4. Clostridium perfringens: (the causative organism of gas gangrene).
5. The causative organism of a a necrotizing wound with a purplish. black
discoloration: most likely produces an alpha toxin virulence factor
6. With Von Willebrand's: the only laboratory abnormality is increased bleeding
time (literally you prick the patient and see how long it takes them to stop bleeding).
7. von Willebrand diseaseFrequently, On Step, bleeding women have VWD.
Bleeding boys have hemophilia.: is by far the most common inherited bleeding
diathesis.
8. On the USMLE Step exam: bleeding women have VWD. Bleeding boys have
hemophilia.
9. Autism -like behaviour: resist making eye contact and flapping hands
10. Fragile X Syndrome: Autism-like behaviors (resist making eye contact and
flapping hands) and large testicles after puberty
11. Fragile X Syndrome caused by: trinucleotide repeat expansion
12. RSV is an RNA virus that enters the cell: via a fusion protein (which is the
target of the prophylactic monoclonal antibody drug Palivizumab).*
13. RSV is an RNA virus: causes RSV Bronchialitis
14. RSV is an RNA virus: has a property of mediation of cell entry via fusion
protein
15. ²2adrenergic agonists' effects on smooth muscle: cause dilation of
bronchial passages, vasodilation in muscle and liver, relaxation of uterine muscle,
and release of insulin
16. ²2adrenergic agonists: are primarily used to treat asthma and other pul-
monary disorders, such as COPD bilateral wheezing as a result of a bee sting
,17. The purpose of Rhogam: is to bind to and remove the RhD antigens so that
the mother does not form an immune response against the antigen in fetus' blood.
, 18. Rhogham administration: It's given to at-risk Rh- moms at 28 weeks and at
deliver
19. Mom is group O and baby is RH Negative give: give Rhogham
20. Metformin causes: 1. Hepatic glucose out put to be decreased
2. target tissue glucose uptake and utilization to be increased
21. Metformin(Glucophage): decreases hepatic glucose production, decreases
intestinal absorption of glucose, and improves insulin sensitivity by increasing
peripheral glucose uptake and utilization.*
22. colicky right flank pain that radiates to
the groin and hematuria.
Ultrasound examination of the kidneys shows right-sided hydronephrosis
and a dilated ureter.
Which of the following is most likely to be found on urinalysis?: Uric acid
crystals
23. Neisseria gonorrhoeae gram stain of the
exudate: shows numerous neutrophils, many that contain intracellular gram-neg-
ative diplococci.
24. Neisseria gonorrhoeae: is able to switch out different pilin genes, and for this
reason, prior infection does not confer long-lasting immunity.
25. Gonorrhea: Gonorrhea can change its pilus, which is responsible for adhesion
to host cells and the main antigen to which the host mounts an immune response.
26. Neisseria gonorrhoeae: has the property of antigenic variation which causes
reinfection
27. Neisseria gonorrhoeae: 1.dysuria and a yellow urethral exudate. 2.Gram
stain of the
exudate shows numerous neutrophils, many that contain intracellular gram-nega-
tive diplococci.
3. had three similar
episodes of urethritis over the past 2 years.
28. anorexic: She
appears emaciated. She is 163 cm (5 ft 4 in) tall and weighs 40 kg (88 lb); BMI is
15 kg/
29. Anorexia leads to hypogonadotropic hypogonadism: as the body realizes
that the possibility of nourishing a fetus is zero and gives up the pretense
AND ANSWERS
1. RSV is an RNA virus that enters the cell via a fusion protein: (which is the
target of the prophylactic monoclonal antibody drug Palivizumab)
2. Gram-positive rods in a diabetic foot wound (or a World War I soldier fight-
ing in a trench) means: means Clostridium perfringens (the causative organism
of gas gangrene). Crepitus means gas in the tissues, which is produced as a
byproduct of its highly virulent alpha toxin
3. Crepitus: means gas in the tissues, which is produced as a byproduct of its
highly virulent alpha toxin
4. Clostridium perfringens: (the causative organism of gas gangrene).
5. The causative organism of a a necrotizing wound with a purplish. black
discoloration: most likely produces an alpha toxin virulence factor
6. With Von Willebrand's: the only laboratory abnormality is increased bleeding
time (literally you prick the patient and see how long it takes them to stop bleeding).
7. von Willebrand diseaseFrequently, On Step, bleeding women have VWD.
Bleeding boys have hemophilia.: is by far the most common inherited bleeding
diathesis.
8. On the USMLE Step exam: bleeding women have VWD. Bleeding boys have
hemophilia.
9. Autism -like behaviour: resist making eye contact and flapping hands
10. Fragile X Syndrome: Autism-like behaviors (resist making eye contact and
flapping hands) and large testicles after puberty
11. Fragile X Syndrome caused by: trinucleotide repeat expansion
12. RSV is an RNA virus that enters the cell: via a fusion protein (which is the
target of the prophylactic monoclonal antibody drug Palivizumab).*
13. RSV is an RNA virus: causes RSV Bronchialitis
14. RSV is an RNA virus: has a property of mediation of cell entry via fusion
protein
15. ²2adrenergic agonists' effects on smooth muscle: cause dilation of
bronchial passages, vasodilation in muscle and liver, relaxation of uterine muscle,
and release of insulin
16. ²2adrenergic agonists: are primarily used to treat asthma and other pul-
monary disorders, such as COPD bilateral wheezing as a result of a bee sting
,17. The purpose of Rhogam: is to bind to and remove the RhD antigens so that
the mother does not form an immune response against the antigen in fetus' blood.
, 18. Rhogham administration: It's given to at-risk Rh- moms at 28 weeks and at
deliver
19. Mom is group O and baby is RH Negative give: give Rhogham
20. Metformin causes: 1. Hepatic glucose out put to be decreased
2. target tissue glucose uptake and utilization to be increased
21. Metformin(Glucophage): decreases hepatic glucose production, decreases
intestinal absorption of glucose, and improves insulin sensitivity by increasing
peripheral glucose uptake and utilization.*
22. colicky right flank pain that radiates to
the groin and hematuria.
Ultrasound examination of the kidneys shows right-sided hydronephrosis
and a dilated ureter.
Which of the following is most likely to be found on urinalysis?: Uric acid
crystals
23. Neisseria gonorrhoeae gram stain of the
exudate: shows numerous neutrophils, many that contain intracellular gram-neg-
ative diplococci.
24. Neisseria gonorrhoeae: is able to switch out different pilin genes, and for this
reason, prior infection does not confer long-lasting immunity.
25. Gonorrhea: Gonorrhea can change its pilus, which is responsible for adhesion
to host cells and the main antigen to which the host mounts an immune response.
26. Neisseria gonorrhoeae: has the property of antigenic variation which causes
reinfection
27. Neisseria gonorrhoeae: 1.dysuria and a yellow urethral exudate. 2.Gram
stain of the
exudate shows numerous neutrophils, many that contain intracellular gram-nega-
tive diplococci.
3. had three similar
episodes of urethritis over the past 2 years.
28. anorexic: She
appears emaciated. She is 163 cm (5 ft 4 in) tall and weighs 40 kg (88 lb); BMI is
15 kg/
29. Anorexia leads to hypogonadotropic hypogonadism: as the body realizes
that the possibility of nourishing a fetus is zero and gives up the pretense
