CMAN 272 EXAM 2 QUESTIONS & ANSWERS
To be diagnosed with MDD, you need one of two symptoms - Answer -depressed
mood; apathy/loss of interest
To be diagnosed with MDD, you need 4/7 symptoms - Answer -weight/appetite
changes; sleep disturbances; psychomotor; fatigue; worthlessness; executive
dysfunction; suicidal ideation
Pharmacological management of MDD - Answer -SSRI, NDRI, SNRI, tcas, MAOI
SSRI MOA - Answer -selective serotonin reuptake inhibitor; increases serotonin in body
NDRI MOA - Answer -norepinephrine dopamine reuptake inhibitor
SSRI use - Answer -antidepressant, anxiety (first line)
NRDI use - Answer -depression, smoking cessation
NRDI SE - Answer -weight loss, reduced appetite, insomnia, elevated BP
SSRI SE - Answer -GI upset, n/v, sexual dysfunction
SNRI MOA - Answer -Serotonin norepinephrine reuptake inhibitor
SNRI uses - Answer -depression; somatic pain; co-occuring pain disorder
SNRI SE - Answer -GI upset, n/v, fatigue (take at night), weight loss, sexual
dysfunction
Trazodone, Remeron - Answer -depression; used when patient has sleep dysfunction
(initiating sleep)
Tricyclic (tcas) MOA - Answer -increases all monoamines
TCA SE - Answer -weight gain, dry mouth, sedation, cardiac effects
MAOI Example - Answer -Nardil
MAOI consideration - Answer -tyramine free diet
MAOI major issue - Answer -hypertensive crisis
To be diagnosed with MDD, you need one of two symptoms - Answer -depressed
mood; apathy/loss of interest
To be diagnosed with MDD, you need 4/7 symptoms - Answer -weight/appetite
changes; sleep disturbances; psychomotor; fatigue; worthlessness; executive
dysfunction; suicidal ideation
Pharmacological management of MDD - Answer -SSRI, NDRI, SNRI, tcas, MAOI
SSRI MOA - Answer -selective serotonin reuptake inhibitor; increases serotonin in body
NDRI MOA - Answer -norepinephrine dopamine reuptake inhibitor
SSRI use - Answer -antidepressant, anxiety (first line)
NRDI use - Answer -depression, smoking cessation
NRDI SE - Answer -weight loss, reduced appetite, insomnia, elevated BP
SSRI SE - Answer -GI upset, n/v, sexual dysfunction
SNRI MOA - Answer -Serotonin norepinephrine reuptake inhibitor
SNRI uses - Answer -depression; somatic pain; co-occuring pain disorder
SNRI SE - Answer -GI upset, n/v, fatigue (take at night), weight loss, sexual
dysfunction
Trazodone, Remeron - Answer -depression; used when patient has sleep dysfunction
(initiating sleep)
Tricyclic (tcas) MOA - Answer -increases all monoamines
TCA SE - Answer -weight gain, dry mouth, sedation, cardiac effects
MAOI Example - Answer -Nardil
MAOI consideration - Answer -tyramine free diet
MAOI major issue - Answer -hypertensive crisis
