HESI PHARMACOLOGY V1 EXAM 2025–2026 ACCURATE
REAL EXAM QUESTIONS AND VERIFIED CORRECT
ANSWERS FULLY UPDATED
THIS EXAM CONTAINS
..100%sure pass
..multiple choice (single best answer)
..multiple responce
,A client has been taking isoniazid (INH) for 2 months. The client complains to a nurse about
numbness, paresthesias, and tingling in the extremities. The nurse interprets that the client is
experiencing:
1. Hypercalcemia
2. Peripheral neuritis
3. Small blood vessel spasm
4. Impaired peripheral circulation - answer>>>2. Peripheral neuritis
Rationale:A common side effect of the TB drug INH is peripheral neuritis. This is manifested by
numbness, tingling, and paresthesia in the extremities. This side effect can be minimized by
pyridoxine (vitamin B6) intake. Options 1, 3, and 4 are incorrect.
A client is to begin a 6-month course of therapy with isoniazid (INH). A nurse plans to teach the
client to:
1. Drink alcohol in small amounts only.
2. Report yellow eyes or skin immediately.
3. Increase intake of Swiss or aged cheeses. 4. Avoid vitamin supplements during therapy. -
answer>>>2. Report yellow eyes or skin immediately.
Rationale:
INH is hepatotoxic, and therefore the client is taught to report signs and symptoms of hepatitis
immediately (which include yellow skin and sclera). For the same reason, alcohol should be
avoided during therapy. The client should avoid intake of Swiss cheese, fish such as tuna, and
foods containing tyramine because they may cause a reaction characterized by redness and
itching of the skin, flushing, sweating, tachycardia, headache, or lightheadedness. The client can
avoid developing peripheral neuritis by increasing the intake of pyridoxine (vitamin B6) during the
course of INH therapy for TB.
A client has been started on long-term therapy with rifampin (Rifadin). A nurse teaches the client
that the medication:
,1. Should always be taken with food or antacids
2. Should be double-dosed if one dose is forgotten
3. Causes orange discoloration of sweat, tears, urine, and feces
4. May be discontinued independently if symptoms are gone in 3 months - answer>>>3. Causes
orange discoloration of sweat, tears, urine, and feces
Rationale:
Rifampin should be taken exactly as directed as part of TB therapy. Doses should not be doubled
or skipped. The client should not stop therapy until directed to do so by a health care provider.
The medication should be administered on an empty stomach unless it causes gastrointestinal
upset, and then it may be taken with food. Antacids, if prescribed, should be taken at least 1 hour
before the medication. Rifampin causes orange-red discoloration of body secretions and will
permanently stain soft contact lenses.
A nurse has given a client taking ethambutol (Myambutol) information about the medication. The
nurse determines that the client understands the instructions if the client states that he or she
will immediately report:
1. Impaired sense of hearing
2. Problems with visual acuity
3. Gastrointestinal (GI) side effects
4. Orange-red discoloration of body secretions - answer>>>2. Problems with visual acuity
Rationale:
Ethambutol causes optic neuritis, which decreases visual acuity and the ability to discriminate
between the colors red and green. This poses a potential safety hazard when a client is driving a
motor vehicle. The client is taught to report this symptom immediately. The client is also taught to
take the medication with food if GI upset occurs. Impaired hearing results from antitubercular
therapy with streptomycin. Orange-red discoloration of secretions occurs with rifampin (Rifadin).
Cycloserine (Seromycin) is added to the medication regimen for a client with tuberculosis. Which
of the following would the nurse include in the client-teaching plan regarding this medication?1
. To take the medication before meals
2. To return to the clinic weekly for serum drug-level testing
3. It is not necessary to call the health care provider (HCP) if a skin rash occurs.
4. It is not necessary to restrict alcohol intake with this medication. - answer>>>2. To return to the
clinic weekly for serum drug-level testing
, Rationale:
Cycloserine (Seromycin) is an antitubercular medication that requires weekly serum drug level
determinations to monitor for the potential of neurotoxicity. Serum drug levels lower than 30
mcg/mL reduce the incidence of neurotoxicity. The medication must be taken after meals to
prevent gastrointestinal irritation. The client must be instructed to notify the HCP if a skin rash or
signs of central nervous system toxicity are noted. Alcohol must be avoided because it increases
the risk of seizure activity.
A client with tuberculosis is being started on antituberculosis therapy with isoniazid (INH). Before
giving the client the first dose, a nurse ensures that which of the following baseline studies has
been completed?
1. Electrolyte levels
2. Coagulation times
3. Liver enzyme levels
4. Serum creatinine level - answer>>>3. Liver enzyme levels
Rationale:
INH therapy can cause an elevation of hepatic enzyme levels and hepatitis. Therefore, liver
enzyme levels are monitored when therapy is initiated and during the first 3 months of therapy.
They may be monitored longer in the client who is greater than age 50 or abuses alcohol.
Rifabutin (Mycobutin) is prescribed for a client with active Mycobacterium avium complex (MAC)
disease and tuberculosis. The nurse monitors for which side effects of the medication? Select all
that apply.
1. Signs of hepatitis
2. Flu-like syndrome
3. Low neutrophil count
4. Vitamin B6 deficiency
5. Ocular pain or blurred vision
6. Tingling and numbness of the fingers - answer>>>1. Signs of hepatitis
2. Flu-like syndrome
3. Low neutrophil count
5. Ocular pain or blurred vision
Rationale:
REAL EXAM QUESTIONS AND VERIFIED CORRECT
ANSWERS FULLY UPDATED
THIS EXAM CONTAINS
..100%sure pass
..multiple choice (single best answer)
..multiple responce
,A client has been taking isoniazid (INH) for 2 months. The client complains to a nurse about
numbness, paresthesias, and tingling in the extremities. The nurse interprets that the client is
experiencing:
1. Hypercalcemia
2. Peripheral neuritis
3. Small blood vessel spasm
4. Impaired peripheral circulation - answer>>>2. Peripheral neuritis
Rationale:A common side effect of the TB drug INH is peripheral neuritis. This is manifested by
numbness, tingling, and paresthesia in the extremities. This side effect can be minimized by
pyridoxine (vitamin B6) intake. Options 1, 3, and 4 are incorrect.
A client is to begin a 6-month course of therapy with isoniazid (INH). A nurse plans to teach the
client to:
1. Drink alcohol in small amounts only.
2. Report yellow eyes or skin immediately.
3. Increase intake of Swiss or aged cheeses. 4. Avoid vitamin supplements during therapy. -
answer>>>2. Report yellow eyes or skin immediately.
Rationale:
INH is hepatotoxic, and therefore the client is taught to report signs and symptoms of hepatitis
immediately (which include yellow skin and sclera). For the same reason, alcohol should be
avoided during therapy. The client should avoid intake of Swiss cheese, fish such as tuna, and
foods containing tyramine because they may cause a reaction characterized by redness and
itching of the skin, flushing, sweating, tachycardia, headache, or lightheadedness. The client can
avoid developing peripheral neuritis by increasing the intake of pyridoxine (vitamin B6) during the
course of INH therapy for TB.
A client has been started on long-term therapy with rifampin (Rifadin). A nurse teaches the client
that the medication:
,1. Should always be taken with food or antacids
2. Should be double-dosed if one dose is forgotten
3. Causes orange discoloration of sweat, tears, urine, and feces
4. May be discontinued independently if symptoms are gone in 3 months - answer>>>3. Causes
orange discoloration of sweat, tears, urine, and feces
Rationale:
Rifampin should be taken exactly as directed as part of TB therapy. Doses should not be doubled
or skipped. The client should not stop therapy until directed to do so by a health care provider.
The medication should be administered on an empty stomach unless it causes gastrointestinal
upset, and then it may be taken with food. Antacids, if prescribed, should be taken at least 1 hour
before the medication. Rifampin causes orange-red discoloration of body secretions and will
permanently stain soft contact lenses.
A nurse has given a client taking ethambutol (Myambutol) information about the medication. The
nurse determines that the client understands the instructions if the client states that he or she
will immediately report:
1. Impaired sense of hearing
2. Problems with visual acuity
3. Gastrointestinal (GI) side effects
4. Orange-red discoloration of body secretions - answer>>>2. Problems with visual acuity
Rationale:
Ethambutol causes optic neuritis, which decreases visual acuity and the ability to discriminate
between the colors red and green. This poses a potential safety hazard when a client is driving a
motor vehicle. The client is taught to report this symptom immediately. The client is also taught to
take the medication with food if GI upset occurs. Impaired hearing results from antitubercular
therapy with streptomycin. Orange-red discoloration of secretions occurs with rifampin (Rifadin).
Cycloserine (Seromycin) is added to the medication regimen for a client with tuberculosis. Which
of the following would the nurse include in the client-teaching plan regarding this medication?1
. To take the medication before meals
2. To return to the clinic weekly for serum drug-level testing
3. It is not necessary to call the health care provider (HCP) if a skin rash occurs.
4. It is not necessary to restrict alcohol intake with this medication. - answer>>>2. To return to the
clinic weekly for serum drug-level testing
, Rationale:
Cycloserine (Seromycin) is an antitubercular medication that requires weekly serum drug level
determinations to monitor for the potential of neurotoxicity. Serum drug levels lower than 30
mcg/mL reduce the incidence of neurotoxicity. The medication must be taken after meals to
prevent gastrointestinal irritation. The client must be instructed to notify the HCP if a skin rash or
signs of central nervous system toxicity are noted. Alcohol must be avoided because it increases
the risk of seizure activity.
A client with tuberculosis is being started on antituberculosis therapy with isoniazid (INH). Before
giving the client the first dose, a nurse ensures that which of the following baseline studies has
been completed?
1. Electrolyte levels
2. Coagulation times
3. Liver enzyme levels
4. Serum creatinine level - answer>>>3. Liver enzyme levels
Rationale:
INH therapy can cause an elevation of hepatic enzyme levels and hepatitis. Therefore, liver
enzyme levels are monitored when therapy is initiated and during the first 3 months of therapy.
They may be monitored longer in the client who is greater than age 50 or abuses alcohol.
Rifabutin (Mycobutin) is prescribed for a client with active Mycobacterium avium complex (MAC)
disease and tuberculosis. The nurse monitors for which side effects of the medication? Select all
that apply.
1. Signs of hepatitis
2. Flu-like syndrome
3. Low neutrophil count
4. Vitamin B6 deficiency
5. Ocular pain or blurred vision
6. Tingling and numbness of the fingers - answer>>>1. Signs of hepatitis
2. Flu-like syndrome
3. Low neutrophil count
5. Ocular pain or blurred vision
Rationale:
