8/21/25, 8:10 PM NUR 500 Exam 2 Flashcards | Quizlet
NURS 500 Advanced Pathophysiology –MSN Nursing
Exam 2 Guide & study material \complete questions and
accurate detailed answers \verified 100%
How do drugs treat By targeting specific physiological pathways (e.g.,
hypertension, heart failure, beta-blockers reduce cardiac workload, SSRIs
and depression (specifically increase serotonin levels, ACE inhibitors reduce
for each)? vasoconstriction).
What are common side effects Beta-blockers: bradycardia, fatigue,
of each: erectile dysfunction Clonidine:
rebound hypertension
-beta-blockers MAOIs: hypertensive crisis with tyramine-containing foods.
-clonidine
-MAOIs
Oral contraceptives can reduce lamotrigine levels, requiring dose
What interaction occurs
adjustments.
between lamotrigine and oral
contraceptives? Lamotrigine is an anti-seizure medication
Why is patient adherence to Ensures therapeutic effectiveness, reduces side effects, and
medication important? prevents complications.
What are first-line drugs SSRIs and SNRIs
for anxiety and expected response takes 3-4 weeks for full therapeutic effect
depression? How long do
the expected responses
take?
Are there routine lab No!
monitoring for SSRIs?
What is the boxed warning of Boxed warning of rare, severe liver toxicity
SNRIs?
/ 1/1
8
,8/21/25, 8:10 PM NUR 500 Exam 2 Flashcards | Quizlet
Monitor for:
-bp
-suicidal ideation, manic symptoms
-liver function
SNRI: Monitoring and
education points Patient education:
-adherence
-suicidal ideation
-avoid abrupt cessation
How are sexual dysfunction, Dose adjustments, switching medications, or adding adjunct
nausea, and GI distress therapies.
managed with
antidepressants?
Why is paroxetine's short It increases the risk of withdrawal symptoms if stopped abruptly.
half-life important?
How should SSRIs be tapered? Gradually over weeks to avoid withdrawal symptoms.
How does obesity contribute Through a hyperinflammatory state involving adipokines
to type 2 diabetes? and insulin resistance (which increases the risk for type
2 diabetes)
Ghrelin (orexigenic,
What are key appetite-
stimulates appetite) and
regulating hormones?
leptin (anorexigenic, suppresses appetite).
What should patients be Medication cost, side effects, and the need for lifestyle changes.
counseled on when using
obesity medications?
What obesity medication is Phentermine/topiramate
the preferred choice for
patients with obesity and a
history of migraines?
What is the benefit of 5% Reduces risk of type 2 diabetes, hypertension, and
weight loss? hyperlipidemia.
Age-related changes in metabolism and drug elimination increase
Why start low and go slow
the risk of toxicity.
when prescribing with
older adults? --> especially in drugs with a narrow therapeutic window (like
Digoxin)
/ 2/1
8
, 8/21/25, 8:10 PM NUR 500 Exam 2 Flashcards | Quizlet
What is an example of a Albumin!
plasma protein?
Increases free drug levels, heightening toxicity risk.
How does decreased
albumin impact drug levels?
--> adjust dose accordingly, especially for drugs that are highly
protein-bound
How does aging affect Decreased GFR and tubular secretion require dose adjustments.
renal drug clearance?
-->this may require lower doses or longer dosing
How might this impact your intervals for medications that are renally cleared?
prescribing?
Why is it important to review To prevent drug interactions, contraindications, and duplications.
all
medications, including OTC
and herbal supplements?
How does doxazosin help with Relaxes bladder neck smooth muscle to improve urine flow.
BPH?
Off-label uses of clonidine: ADHD
Clonidine has off-label uses Opioid withdrawal
in managing what two
things?
/ 3/1
8
NURS 500 Advanced Pathophysiology –MSN Nursing
Exam 2 Guide & study material \complete questions and
accurate detailed answers \verified 100%
How do drugs treat By targeting specific physiological pathways (e.g.,
hypertension, heart failure, beta-blockers reduce cardiac workload, SSRIs
and depression (specifically increase serotonin levels, ACE inhibitors reduce
for each)? vasoconstriction).
What are common side effects Beta-blockers: bradycardia, fatigue,
of each: erectile dysfunction Clonidine:
rebound hypertension
-beta-blockers MAOIs: hypertensive crisis with tyramine-containing foods.
-clonidine
-MAOIs
Oral contraceptives can reduce lamotrigine levels, requiring dose
What interaction occurs
adjustments.
between lamotrigine and oral
contraceptives? Lamotrigine is an anti-seizure medication
Why is patient adherence to Ensures therapeutic effectiveness, reduces side effects, and
medication important? prevents complications.
What are first-line drugs SSRIs and SNRIs
for anxiety and expected response takes 3-4 weeks for full therapeutic effect
depression? How long do
the expected responses
take?
Are there routine lab No!
monitoring for SSRIs?
What is the boxed warning of Boxed warning of rare, severe liver toxicity
SNRIs?
/ 1/1
8
,8/21/25, 8:10 PM NUR 500 Exam 2 Flashcards | Quizlet
Monitor for:
-bp
-suicidal ideation, manic symptoms
-liver function
SNRI: Monitoring and
education points Patient education:
-adherence
-suicidal ideation
-avoid abrupt cessation
How are sexual dysfunction, Dose adjustments, switching medications, or adding adjunct
nausea, and GI distress therapies.
managed with
antidepressants?
Why is paroxetine's short It increases the risk of withdrawal symptoms if stopped abruptly.
half-life important?
How should SSRIs be tapered? Gradually over weeks to avoid withdrawal symptoms.
How does obesity contribute Through a hyperinflammatory state involving adipokines
to type 2 diabetes? and insulin resistance (which increases the risk for type
2 diabetes)
Ghrelin (orexigenic,
What are key appetite-
stimulates appetite) and
regulating hormones?
leptin (anorexigenic, suppresses appetite).
What should patients be Medication cost, side effects, and the need for lifestyle changes.
counseled on when using
obesity medications?
What obesity medication is Phentermine/topiramate
the preferred choice for
patients with obesity and a
history of migraines?
What is the benefit of 5% Reduces risk of type 2 diabetes, hypertension, and
weight loss? hyperlipidemia.
Age-related changes in metabolism and drug elimination increase
Why start low and go slow
the risk of toxicity.
when prescribing with
older adults? --> especially in drugs with a narrow therapeutic window (like
Digoxin)
/ 2/1
8
, 8/21/25, 8:10 PM NUR 500 Exam 2 Flashcards | Quizlet
What is an example of a Albumin!
plasma protein?
Increases free drug levels, heightening toxicity risk.
How does decreased
albumin impact drug levels?
--> adjust dose accordingly, especially for drugs that are highly
protein-bound
How does aging affect Decreased GFR and tubular secretion require dose adjustments.
renal drug clearance?
-->this may require lower doses or longer dosing
How might this impact your intervals for medications that are renally cleared?
prescribing?
Why is it important to review To prevent drug interactions, contraindications, and duplications.
all
medications, including OTC
and herbal supplements?
How does doxazosin help with Relaxes bladder neck smooth muscle to improve urine flow.
BPH?
Off-label uses of clonidine: ADHD
Clonidine has off-label uses Opioid withdrawal
in managing what two
things?
/ 3/1
8
