MIP 420 Exam 3 Questions And Answers
100% Complete
Hepadnaviridae replication initiation - answer De novo initiation by RdRp at first
nucleotide
Hepadnaviridae replication ends - answer Terminal repeats: DNA jumping (RT)
Hepadnaviridae 5' 7 Methyl cap - answer Has a 5' 7 Methyl cap?
Hepadnaviridae poly A tail? - answer Has poly A tail?
Hepadnaviridae monocistronic solution? - answer Differential splicing (in nucleus)
Retroviridae replication initiation - answer tRNA binds to 3'OH used by RT to initiate
DNA replication
Retroviridae replication ends - answer Terminal repeats: DNA jumping (RT)
Retroviridae 5' 7 Methyl cap - answer Has a 5' 7 Methyl cap
Retroviridae 3' poly A tail? - answer Has a 3' poly A tail
Retroviridae monocistronic solution? (5 things) - answer Differential splicing (in
nucleus), viral protease, frame shifting/overlapping ORFS, leaky ribosomal scanning,
termination suppression
Picornaviridae replication initiation - answer Serine, threonine, or tyrosine provide OH
group for RdRp to add nucleotides to
Picornaviridae replication ends - answer Serine, threonine, or tyrosine provide OH
group for DNA Pol to add nucleotides to
Picornaviridae 5' 7 Methyl cap - answer IRES (Internal ribosome entry site) bings
ribosome and compensates for lack of 5' 7 Methyl cap
Picornaviridae poly A tail? - answer Stuttering of RdRp at short poly U track creates long
poly A tail
Picornaviridae monocistronic solution? - answer Viral protease
Flaviviridae replication initiation - answer De novo initiation by RdRp at first nucleotide
, Flaviviridae replication ends - answer RdRp begins synthesis at primerless end
Flaviviridae 5' 7 Methyl cap - answer IRES (Internal ribosome entry site) bings ribosome
and compensates for lack of 5' 7 Methyl cap
Flaviviridae poly A tail? - answer PABP binds to structure on 3' end (without poly-A tail)
Flaviviridae monocistronic solution? - answer Viral protease
Togaviridae replication initiation - answer De novo initiation by RdRp at first nucleotide
Togaviridae replication ends - answer RdRp begins synthesis at primerless end
Togaviridae 5' 7 Methyl cap - answer Viral cap-adding proteins compensate for lack of 5'
7 Methyl cap
Togaviridae poly A tail? - answer PABP binds to structure on 3' end (without poly-A tail)
Togaviridae monocistronic solution? (3 things) - answer Subgenomic mRNA read from -
sense strand, viral proteases, termination suppression
Caliciviridae replication initiation - answer Serine, threonine, or tyrosine provide OH
group for RdRp to add nucleotides to
Caliciviridae replication ends - answer Serine, threonine, or tyrosine provide OH group
for DNA Pol to add nucleotides to
Caliciviridae 5' 7 Methyl cap - answer IRES (Internal ribosome entry site) bings ribosome
and compensates for lack of 5' 7 Methyl cap
Caliciviridae poly A tail? - answer Stuttering of RdRp at short poly U track creates long
poly A tail
Caliciviridae monocistronic solution? (2 things) - answer Subgenomic mRNA read from -
sense strand, viral proteases
Coronaviridae replication initiation - answer De novo initiation by RdRp at first
nucleotide
Coronaviridae replication ends - answer RdRp begins synthesis at primerless end
100% Complete
Hepadnaviridae replication initiation - answer De novo initiation by RdRp at first
nucleotide
Hepadnaviridae replication ends - answer Terminal repeats: DNA jumping (RT)
Hepadnaviridae 5' 7 Methyl cap - answer Has a 5' 7 Methyl cap?
Hepadnaviridae poly A tail? - answer Has poly A tail?
Hepadnaviridae monocistronic solution? - answer Differential splicing (in nucleus)
Retroviridae replication initiation - answer tRNA binds to 3'OH used by RT to initiate
DNA replication
Retroviridae replication ends - answer Terminal repeats: DNA jumping (RT)
Retroviridae 5' 7 Methyl cap - answer Has a 5' 7 Methyl cap
Retroviridae 3' poly A tail? - answer Has a 3' poly A tail
Retroviridae monocistronic solution? (5 things) - answer Differential splicing (in
nucleus), viral protease, frame shifting/overlapping ORFS, leaky ribosomal scanning,
termination suppression
Picornaviridae replication initiation - answer Serine, threonine, or tyrosine provide OH
group for RdRp to add nucleotides to
Picornaviridae replication ends - answer Serine, threonine, or tyrosine provide OH
group for DNA Pol to add nucleotides to
Picornaviridae 5' 7 Methyl cap - answer IRES (Internal ribosome entry site) bings
ribosome and compensates for lack of 5' 7 Methyl cap
Picornaviridae poly A tail? - answer Stuttering of RdRp at short poly U track creates long
poly A tail
Picornaviridae monocistronic solution? - answer Viral protease
Flaviviridae replication initiation - answer De novo initiation by RdRp at first nucleotide
, Flaviviridae replication ends - answer RdRp begins synthesis at primerless end
Flaviviridae 5' 7 Methyl cap - answer IRES (Internal ribosome entry site) bings ribosome
and compensates for lack of 5' 7 Methyl cap
Flaviviridae poly A tail? - answer PABP binds to structure on 3' end (without poly-A tail)
Flaviviridae monocistronic solution? - answer Viral protease
Togaviridae replication initiation - answer De novo initiation by RdRp at first nucleotide
Togaviridae replication ends - answer RdRp begins synthesis at primerless end
Togaviridae 5' 7 Methyl cap - answer Viral cap-adding proteins compensate for lack of 5'
7 Methyl cap
Togaviridae poly A tail? - answer PABP binds to structure on 3' end (without poly-A tail)
Togaviridae monocistronic solution? (3 things) - answer Subgenomic mRNA read from -
sense strand, viral proteases, termination suppression
Caliciviridae replication initiation - answer Serine, threonine, or tyrosine provide OH
group for RdRp to add nucleotides to
Caliciviridae replication ends - answer Serine, threonine, or tyrosine provide OH group
for DNA Pol to add nucleotides to
Caliciviridae 5' 7 Methyl cap - answer IRES (Internal ribosome entry site) bings ribosome
and compensates for lack of 5' 7 Methyl cap
Caliciviridae poly A tail? - answer Stuttering of RdRp at short poly U track creates long
poly A tail
Caliciviridae monocistronic solution? (2 things) - answer Subgenomic mRNA read from -
sense strand, viral proteases
Coronaviridae replication initiation - answer De novo initiation by RdRp at first
nucleotide
Coronaviridae replication ends - answer RdRp begins synthesis at primerless end
