KU BIOL 600 EXAM 3 2025 QUESTIONS AND ANSWERS
Which enzymes catalyze the synthesis of phosphoenolpyruvate from pyruvate and a phosphate group
during gluconeogenesis? - (answer)pyruvate carboxylase and phosphoenol pyruvate carboxykinase
What mitochondrial transport protein is utilized during the synthesis of phosphoenolpyruvate from
pyruvate and a phosphate group during gluconeogenesis? - (answer)malate transporter
Prior to entry of gluconeogenesis, ________ is converted into pyruvate, and some _________ are
converted to oxaloacetate - (answer)lactate and amino acids
What are the three inhibitors of phophofructosekinase? - (answer)ATP Citrate and H+
In gluconeogenesis, name the two inhibitors of fructose 1,6 bisphosphate - (answer)AMP and fructose
2,6 bisphosphate
In gluconeogenesis, pyruvate carboxylase is inhibited by _______ and stimulated by _________ -
(answer)ADP and acetyl coA
Complete this sentence that describes the Cori Cycle: ______ from ______ is transported in ________ to
the ______ where it is converted to glucose - (answer)lactate muscle blood liver
Pyvurate carboxylase requires the vitamin cofactor ____, which serves as a carrier of activated CO2 -
(answer)biotin
What peptide hormone is released when blood glucose concentration is low? - (answer)glucagon
This stimulates the increase of ______ which stimulates ______ and inhibits ________ - (answer)
Where is glucose-6-phosphatase found? what does it supply? - (answer)ER
Glucose
, KU BIOL 600 EXAM 3 2025 QUESTIONS AND ANSWERS
What is pyruvate carboxylase activated by? - (answer)Acetyl CoA
What is pyruvate carboxylase inhibited by? - (answer)ADP
What is the substrate for glycogen synthesis? - (answer)UDP-glucose
What is the role of glycogenin? - (answer)It makes the primer for glycogen synthesis
What is the enzyme that removes glucose units from the non-reducing ends of the glycogen molecule
called? - (answer)glycogen phosphorylase
Glycogen phosphorylase is activated by what protein modification - (answer)phosphorylation
What two hormones maintain blood glucose levels within a normal range? - (answer)insulin and
glucagon
How does protein phosphate 1 regulate glycogen phosphorylate? - (answer)by removing the phosphate
group from glycogen synthase, which activates glycogen synthase
How is the role of AMP in allosteric control of glycogen metabolism? - (answer)AMP stimulates glycogen
phosphorylase and inhibits glycogen synthase
What is the role of glucose 6-phosphate in allosteric control of glycogen metabolism? - (answer)Glucose
6-phosphate stimulates glycogen synthase and inhibits glycogen phosphorylase.
What is the debranching enzyme used in the breakdown of glycogen? - (answer)alpha 1,6 glucosidase
What enzyme shifts a small oligosaccharide near a branch point of glycogen into a nearby chan? -
(answer)transferase
Which enzymes catalyze the synthesis of phosphoenolpyruvate from pyruvate and a phosphate group
during gluconeogenesis? - (answer)pyruvate carboxylase and phosphoenol pyruvate carboxykinase
What mitochondrial transport protein is utilized during the synthesis of phosphoenolpyruvate from
pyruvate and a phosphate group during gluconeogenesis? - (answer)malate transporter
Prior to entry of gluconeogenesis, ________ is converted into pyruvate, and some _________ are
converted to oxaloacetate - (answer)lactate and amino acids
What are the three inhibitors of phophofructosekinase? - (answer)ATP Citrate and H+
In gluconeogenesis, name the two inhibitors of fructose 1,6 bisphosphate - (answer)AMP and fructose
2,6 bisphosphate
In gluconeogenesis, pyruvate carboxylase is inhibited by _______ and stimulated by _________ -
(answer)ADP and acetyl coA
Complete this sentence that describes the Cori Cycle: ______ from ______ is transported in ________ to
the ______ where it is converted to glucose - (answer)lactate muscle blood liver
Pyvurate carboxylase requires the vitamin cofactor ____, which serves as a carrier of activated CO2 -
(answer)biotin
What peptide hormone is released when blood glucose concentration is low? - (answer)glucagon
This stimulates the increase of ______ which stimulates ______ and inhibits ________ - (answer)
Where is glucose-6-phosphatase found? what does it supply? - (answer)ER
Glucose
, KU BIOL 600 EXAM 3 2025 QUESTIONS AND ANSWERS
What is pyruvate carboxylase activated by? - (answer)Acetyl CoA
What is pyruvate carboxylase inhibited by? - (answer)ADP
What is the substrate for glycogen synthesis? - (answer)UDP-glucose
What is the role of glycogenin? - (answer)It makes the primer for glycogen synthesis
What is the enzyme that removes glucose units from the non-reducing ends of the glycogen molecule
called? - (answer)glycogen phosphorylase
Glycogen phosphorylase is activated by what protein modification - (answer)phosphorylation
What two hormones maintain blood glucose levels within a normal range? - (answer)insulin and
glucagon
How does protein phosphate 1 regulate glycogen phosphorylate? - (answer)by removing the phosphate
group from glycogen synthase, which activates glycogen synthase
How is the role of AMP in allosteric control of glycogen metabolism? - (answer)AMP stimulates glycogen
phosphorylase and inhibits glycogen synthase
What is the role of glucose 6-phosphate in allosteric control of glycogen metabolism? - (answer)Glucose
6-phosphate stimulates glycogen synthase and inhibits glycogen phosphorylase.
What is the debranching enzyme used in the breakdown of glycogen? - (answer)alpha 1,6 glucosidase
What enzyme shifts a small oligosaccharide near a branch point of glycogen into a nearby chan? -
(answer)transferase
