GMS 6401 MOCK EXAM UPDATED QUESTIONS AND ANSWERS
The kidney consists of specialized vascular and tubular structures (the nephron) which collaborate in the
production of urine: - CORRECT ANSWER✅✅The glomerular capillary is surrounded by an epithelial
structure which forms the beginning of the tubule.
A diagnostic renal clearance experiment is conducted and the following steady state (= equilibrium)
measurements are obtained on a 34 year old male subject, weighing 60 kg (assume that the renal
plasma flow (RPF) is the same as the effective renal plasma flow (ERPF):
Urine inulin = 200 mg/100ml
Plasma inulin = 4 mg/100ml
Urine flow (V) = 2ml/min
Urine PAH = 1200 mg/100ml
Plasma PAH = 6 mg/100ml - CORRECT ANSWER✅✅GFR = 100ml/min
Any substance which is freely filtered at the glomerulus, is reabsorbed and is not secreted, will have a
renal clearance that is: Choose one best answer. - CORRECT ANSWER✅✅Less than the clearance of
inulin
An increased protein excretion (proteinuria) can indicate glomerular damage. Which of the following
changes are likely to cause proteinuria? Choose 1 best answer: - CORRECT ANSWER✅✅Loss of nephrin
from the epithelial slit pore diaphragm
Maintenance of a high glomerular filtration rate (GFR) is required for optimal kidney function. Which of
the following options would be most likely to associate with a below optimal GFR in man? - CORRECT
ANSWER✅✅A low glomerular capillary water permeability
A selective increase in renal plasma flow (RPF) due to parallel relaxation of theafferent and efferent
arterioles leads to: (Choose one best answer.) - CORRECT ANSWER✅✅A rise in GFR with no change in
filtration fraction
An increase in renal blood flow will lead to which of the following changes within the kidney: (Choose
one best answer.) - CORRECT ANSWER✅✅Increased total renal oxygen consumption but little change in
the renal venous oxygen content (arterial - venous difference)
The kidney consists of specialized vascular and tubular structures (the nephron) which collaborate in the
production of urine: - CORRECT ANSWER✅✅The glomerular capillary is surrounded by an epithelial
structure which forms the beginning of the tubule.
A diagnostic renal clearance experiment is conducted and the following steady state (= equilibrium)
measurements are obtained on a 34 year old male subject, weighing 60 kg (assume that the renal
plasma flow (RPF) is the same as the effective renal plasma flow (ERPF):
Urine inulin = 200 mg/100ml
Plasma inulin = 4 mg/100ml
Urine flow (V) = 2ml/min
Urine PAH = 1200 mg/100ml
Plasma PAH = 6 mg/100ml - CORRECT ANSWER✅✅GFR = 100ml/min
Any substance which is freely filtered at the glomerulus, is reabsorbed and is not secreted, will have a
renal clearance that is: Choose one best answer. - CORRECT ANSWER✅✅Less than the clearance of
inulin
An increased protein excretion (proteinuria) can indicate glomerular damage. Which of the following
changes are likely to cause proteinuria? Choose 1 best answer: - CORRECT ANSWER✅✅Loss of nephrin
from the epithelial slit pore diaphragm
Maintenance of a high glomerular filtration rate (GFR) is required for optimal kidney function. Which of
the following options would be most likely to associate with a below optimal GFR in man? - CORRECT
ANSWER✅✅A low glomerular capillary water permeability
A selective increase in renal plasma flow (RPF) due to parallel relaxation of theafferent and efferent
arterioles leads to: (Choose one best answer.) - CORRECT ANSWER✅✅A rise in GFR with no change in
filtration fraction
An increase in renal blood flow will lead to which of the following changes within the kidney: (Choose
one best answer.) - CORRECT ANSWER✅✅Increased total renal oxygen consumption but little change in
the renal venous oxygen content (arterial - venous difference)
