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NCLEX RN Questions with Answers – Top Medications for the NCLEX Exam

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This document provides a comprehensive set of NCLEX RN practice questions with detailed answers, focusing on the most frequently tested medications. It covers drug classifications, mechanisms of action, side effects, contraindications, and nursing considerations for safe administration. Content includes pharmacology review across multiple specialties such as cardiovascular, respiratory, endocrine, neurological, and psychiatric care. Designed to strengthen medication knowledge and clinical judgment, it helps students prepare for the NCLEX RN with confidence.

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NCLEX Questions with Answers
Top Meds on NCLEX RN
3rd Edition

,Table of Contents
Chapter 1: Ace Inhibitors
Chapter 2: Alpha Blockers
Chapter 3: Angiotensin II Inhibitors
Chapter 4: Antianginals
Chapter 5: Antidysrhytmics
Chapter 6: Antiemetics
Chapter 7: Antifungals
Chapter 8: Antibiotics
Chapter 9: Anticoagulants
Chapter 10: Anti-Depressants
Chapter 11: Antihistamines
Chapter 12: Beta Blockers
Chapter 13: Calcium Channel Blockers
Chapter 14: Antiplatelet
Chapter 15: Benzodiazepines
Chapter 16: Cardiac Glycosides
Chapter 17: Diuretics
Chapter 18: HIV anti agents
Chapter 19: Insulins
Chapter 20: NSAIDS
Chapter 21: Opioid
Chapter 22: Oral Hypoglycemic
Chapter 23: Proton pump inhibitors
Chapter 24: Respiratory
Chapter 25: Statins
Chapter 26: Thrombolytics
Chapter 27: Vasopressors
Chapter 28: Ophthalmic
Chapter 29: OTC Remedies
Chapter 30: Herbal Remedies

, Chapter 1
A Quick Review about ACE Inhibitors
What are ACE Inhibitors?
ACE Inhibitors or Angiotensin Converting Enzymes are any of a group of antihypertensive drugs
that relax arteries and promote renal excretion of salt and water by inhibiting the activity of an
angiotensin converting enzyme.

These are enzymes responsible for reducing vasculature resistance without increasing cardiac
output, rate or contractility.

NCLEX Alert! ACE Inhibitors are one of the most frequently tested antihypertensive drugs on
NCLEX.

These are the diseases that ACE Inhibitors treat:
1. Hypertension
2. Congestive heart failure
And, they lower the risk of stroke and heart attack.

You must remember that these inhibitors have side effects in our body, such as:
1. Postural hypotension (commonly known as ‘head rush’ or ‘dizzy spell’)
2. Fatigue
3. Loss of appetite
4. Nausea, vomiting, diarrhea
5. Hyperkalemia
6. Insomnia
7. Could exacerbate non-productive cough
8. Angiodema

Some of the commonly used ACE Inhibitors are Benazepril, Captopril, Enalapril and Fosinopril.
Also included in this classification are Lisinopril, Moexipril or Perindopril.

Now, what should be your nursing considerations in giving medications? As a nurse, you also
have to educate your clients in taking these drugs. Here are some medical considerations:
1. You have to remember that these medications cause retention of potassium. Hence,
monitor the electrolytes.
2. Take note that elderly clients are at highest risk for postural hypotension.
3. Always instruct your clients not to abruptly discontinue medications because rebound
hypertension can occur.
4. Do not forget to monitor the blood pressure frequently.
5. If your client has impaired renal function, you have to be cautious if they will be using
these drugs
6. Finally, notify the client’s physicians if dizziness still persists.

, Lab. Value Alert:
 Calcium 8.8 - 10.3 mg/dL
 Calcium, ionized 2.24 - 2.46 mEq/L
 Chloride 95 - 107 mEq/L
 Magnesium 1.6 - 2.4 mEq/L
 Phosphate 2.5 - 4.5 mEq/dL
 Potassium 3.6 - 5.2 mmol/L
 Sodium 135 - 145 mEq/L

If your client is on ACE inhibitors, you should see these desirable outcomes:
 Blood pressures controlled within normal limits
 Improved survival rates for clients suffering from acute MI
 Decreased workload on cardiovascular system
 Decrease or absence of chest pain

If you see these positive results, then you are on the right track!

NCLEX Tips to remember about these medications:
Tip #1: Most ACE drugs end with the suffix –pril, as in Ramipril, Quinapril, Trandolapril
Tip #2: If your client is taking diuretics, notify the physician before they take Lisonipril
Tip #3: Always double-check the drugs and their side effects with the client

Frequently Asked Questions (FAQs):
Q: What are the brand names of ACE Inhibitors?
A: Lotensin, Capoten, Vasotec, Monopril, Prinivil, Zestril, etc.

Q: Should the medications be taken immediately after eating?
A: No. The drug's absorption will be decreased if taken with food. So you should allot at least 1
hour before taking the meds.

You are now ready to take these NCLEX sample practice questions. Just remember the
guidelines given to you, and you can answer the following correctly:

1. Which statement, if made by the hypertensive client taking Lisinopril, indicates the
need for further teaching?
a. “I will take the medication with my Spironolactone.”
b. “I will inform the physician if my dizziness persists.”
c. “I will not stand up immediately after taking the medication.”
d. “I will have my daughter take my blood pressure from time to time.”

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