MLT 106 Unit 7 & 8 UPDATED ACTUAL
Exam Questions and CORRECT Answers
Hypersensitivity
*Pg 314* - CORRECT ANSWER - normal but exaggerated or uncontrolled immune
response to an antigen that produces inflammation, cell destruction, or tissue injury
What are the four types of hypersensitivity?
*Pg 314* - CORRECT ANSWER - Type I - Anaphylactic reaction
Type II - Cytotoxic reaction
Type III - Immune complex reaction
Type IV - T cell-dependent
Allergy
*Pg 315* - CORRECT ANSWER - altered reaction to external substances
- Related to immediate hypersensitivity mediated by IgE antibodies
Histamine
*Pg 315* - CORRECT ANSWER - released by mast cells or basophils
What are the two types of an anaphylaxis reaction?
*Pg 315* - CORRECT ANSWER - - Systemic
- Local
Type II: Hypersensitivity Reactions
*Pg 315* - CORRECT ANSWER - Consequences of IgG or IgM binding to the surface of
cells
, What is the test used for Type II Hypersensitivity?
*Pg 315* - CORRECT ANSWER - DAT
What are the 3 different mechanisms for Type II reactions?
*Pg 315* - CORRECT ANSWER - - Antibody-dependent, complement-mediated
cytotoxic reactions
- Antibody-dependent, cell-mediated cytotoxicity
- Antireceptor antibodies
Type III: Immune Complex Reactions
*Pg 316* - CORRECT ANSWER - Deposition of immune complexes in blood vessel
walls and tissues
- Repeated exposure leads to "Arthus Reaction"
Type IV: Cell-Mediated Reactions
*Pg 316* - CORRECT ANSWER - Cell-Mediated immunity between T Lymphocytes and
phagocytic cells
Monoclonal Gammopathies
*Pg 317* - CORRECT ANSWER - Production of monoclonal immunoglobulin (antibody)
- Involved w/ suppression of uninvolved immunoglobulins and dysfunctional T cell responses
Multiple Myeloma
*Pg 317* - CORRECT ANSWER - Accumulation of malignant plasma cells within the
bone marrow microenvironment
MM is the most common form of _________ and accounts for ____ of all types of malignant
diseases and _______ of hematologic malignancies.
*Pg 318* - CORRECT ANSWER - Dysproteinemia; 1%; 10%
Exam Questions and CORRECT Answers
Hypersensitivity
*Pg 314* - CORRECT ANSWER - normal but exaggerated or uncontrolled immune
response to an antigen that produces inflammation, cell destruction, or tissue injury
What are the four types of hypersensitivity?
*Pg 314* - CORRECT ANSWER - Type I - Anaphylactic reaction
Type II - Cytotoxic reaction
Type III - Immune complex reaction
Type IV - T cell-dependent
Allergy
*Pg 315* - CORRECT ANSWER - altered reaction to external substances
- Related to immediate hypersensitivity mediated by IgE antibodies
Histamine
*Pg 315* - CORRECT ANSWER - released by mast cells or basophils
What are the two types of an anaphylaxis reaction?
*Pg 315* - CORRECT ANSWER - - Systemic
- Local
Type II: Hypersensitivity Reactions
*Pg 315* - CORRECT ANSWER - Consequences of IgG or IgM binding to the surface of
cells
, What is the test used for Type II Hypersensitivity?
*Pg 315* - CORRECT ANSWER - DAT
What are the 3 different mechanisms for Type II reactions?
*Pg 315* - CORRECT ANSWER - - Antibody-dependent, complement-mediated
cytotoxic reactions
- Antibody-dependent, cell-mediated cytotoxicity
- Antireceptor antibodies
Type III: Immune Complex Reactions
*Pg 316* - CORRECT ANSWER - Deposition of immune complexes in blood vessel
walls and tissues
- Repeated exposure leads to "Arthus Reaction"
Type IV: Cell-Mediated Reactions
*Pg 316* - CORRECT ANSWER - Cell-Mediated immunity between T Lymphocytes and
phagocytic cells
Monoclonal Gammopathies
*Pg 317* - CORRECT ANSWER - Production of monoclonal immunoglobulin (antibody)
- Involved w/ suppression of uninvolved immunoglobulins and dysfunctional T cell responses
Multiple Myeloma
*Pg 317* - CORRECT ANSWER - Accumulation of malignant plasma cells within the
bone marrow microenvironment
MM is the most common form of _________ and accounts for ____ of all types of malignant
diseases and _______ of hematologic malignancies.
*Pg 318* - CORRECT ANSWER - Dysproteinemia; 1%; 10%
