MLT 106 Test 3; ABO and Rh Blood System
Groups UPDATED ACTUAL Exam
Questions and CORRECT Answers
The ABO system was discovered in 1901 by _____ - CORRECT ANSWER - Karl
Landsteiner
Almost all healthy people older than ____ of age have _______ to the ABO antigens they lack -
CORRECT ANSWER - 3-6 months; naturally occurring antibodies
Landsteiner demonstrated that a person's serum contained antibodies(naturally occurring) against
______ - CORRECT ANSWER - an antigen absent from his own red blood cells; also
termed *isohemagglutinins*
"Landsteiner's Rule" states:
If the ABO *antigen is present on the cells,* ______
If the ABO *antibody is present in the serum,* ______ - CORRECT ANSWER - - the
corresponding *antibody will be absent from the serum*
- the corresponding *antigen will be absent on the cells*
The ABO blood group system remains the most important in ______ and ____ practice. -
CORRECT ANSWER - Transfusion and transplantation
An *incompatible ABO transfusion* results to _______ - CORRECT ANSWER - acute
intravascular hemolysis and renal failure , and can be fatal
Today, ABO typing reagents are manufactured from _____ derived from culture cell lines, which
have several advantages over conventional human and plant ABO reagents. - CORRECT
ANSWER - monoclonal antibodies;
- Major advantages is *reproducibility*
,; undesired antibody specificities are also excluded from the antisera
Anti-A reagent is - CORRECT ANSWER - Blue
Anti-B reagent is - CORRECT ANSWER - Yellow
There is always an ________ between the *forward and reverse type;* thus, one serves as a
check on the other. - CORRECT ANSWER - inverse reciprocal relationship
Phenotype *A* - CORRECT ANSWER - *Forward typing*
+,=
*Reverse typing*
=, +
Phenotype *B* - CORRECT ANSWER - *Forward typing*
=, +
*Reverse typing*
+, =
Phenotype *AB* - CORRECT ANSWER - *Forward typing*
+, +
*Reverse typing*
=, =
Phenotype *O* - CORRECT ANSWER - *Forward typing*
=, =
*Reverse typing*
+, +
, Forward Grouping (also known as front type): - CORRECT ANSWER - Testing for an
individual's ABO antigens( unknown antigens on the red blood cells) using antisera (reagents
with known ABO antibodies)
; Anti-A
; Anti-B
Reverse Grouping (also known as back type) - CORRECT ANSWER - Testing for the
presence or absence of individual ABO antibodies(unknown antibodies) using reagent red blood
cells(known antigens)
; 2 to 4% suspension of Reagent A1 Cells
; 2 to 4% suspension of Reagent B Cells
The major antigens of the ABO systems are: - CORRECT ANSWER -A
B
H(O)
The major antibodies of the ABO system: - CORRECT ANSWER - Anti-A
Anti-B
Anti-A,B
Anti-H
Antibody production *peaks* between ______ and declines later in life - CORRECT
ANSWER - 5 and 10 years of age
Some or all of antibodies present may be _____ of maternal origin that have crossed the
placenta. - CORRECT ANSWER - IgG
______ usually have lower levels of anti-A and anti-B; therefore, antibodies may be undetectable
in the reserve grouping - CORRECT ANSWER - Elderly people
Groups UPDATED ACTUAL Exam
Questions and CORRECT Answers
The ABO system was discovered in 1901 by _____ - CORRECT ANSWER - Karl
Landsteiner
Almost all healthy people older than ____ of age have _______ to the ABO antigens they lack -
CORRECT ANSWER - 3-6 months; naturally occurring antibodies
Landsteiner demonstrated that a person's serum contained antibodies(naturally occurring) against
______ - CORRECT ANSWER - an antigen absent from his own red blood cells; also
termed *isohemagglutinins*
"Landsteiner's Rule" states:
If the ABO *antigen is present on the cells,* ______
If the ABO *antibody is present in the serum,* ______ - CORRECT ANSWER - - the
corresponding *antibody will be absent from the serum*
- the corresponding *antigen will be absent on the cells*
The ABO blood group system remains the most important in ______ and ____ practice. -
CORRECT ANSWER - Transfusion and transplantation
An *incompatible ABO transfusion* results to _______ - CORRECT ANSWER - acute
intravascular hemolysis and renal failure , and can be fatal
Today, ABO typing reagents are manufactured from _____ derived from culture cell lines, which
have several advantages over conventional human and plant ABO reagents. - CORRECT
ANSWER - monoclonal antibodies;
- Major advantages is *reproducibility*
,; undesired antibody specificities are also excluded from the antisera
Anti-A reagent is - CORRECT ANSWER - Blue
Anti-B reagent is - CORRECT ANSWER - Yellow
There is always an ________ between the *forward and reverse type;* thus, one serves as a
check on the other. - CORRECT ANSWER - inverse reciprocal relationship
Phenotype *A* - CORRECT ANSWER - *Forward typing*
+,=
*Reverse typing*
=, +
Phenotype *B* - CORRECT ANSWER - *Forward typing*
=, +
*Reverse typing*
+, =
Phenotype *AB* - CORRECT ANSWER - *Forward typing*
+, +
*Reverse typing*
=, =
Phenotype *O* - CORRECT ANSWER - *Forward typing*
=, =
*Reverse typing*
+, +
, Forward Grouping (also known as front type): - CORRECT ANSWER - Testing for an
individual's ABO antigens( unknown antigens on the red blood cells) using antisera (reagents
with known ABO antibodies)
; Anti-A
; Anti-B
Reverse Grouping (also known as back type) - CORRECT ANSWER - Testing for the
presence or absence of individual ABO antibodies(unknown antibodies) using reagent red blood
cells(known antigens)
; 2 to 4% suspension of Reagent A1 Cells
; 2 to 4% suspension of Reagent B Cells
The major antigens of the ABO systems are: - CORRECT ANSWER -A
B
H(O)
The major antibodies of the ABO system: - CORRECT ANSWER - Anti-A
Anti-B
Anti-A,B
Anti-H
Antibody production *peaks* between ______ and declines later in life - CORRECT
ANSWER - 5 and 10 years of age
Some or all of antibodies present may be _____ of maternal origin that have crossed the
placenta. - CORRECT ANSWER - IgG
______ usually have lower levels of anti-A and anti-B; therefore, antibodies may be undetectable
in the reserve grouping - CORRECT ANSWER - Elderly people
