(MB) ASCP Exam Questions and Answers Latest 2025

What kind of bond do histones have with DNA? - Ionic What amino acids compose histones? - Lysine and Arginine Which lymphoma has t-cell rearrangements? - Sezary Syndrome Acute Promyelocytic leukemia translocation? - t(15,17) Leading strand polymerase: - Delta DNA repair polymerase(s): - Beta or Epsilon Mitochondrial polymerase: - Gamma Molecular beacon design: - (R-sequence-Q) Which method uses visible light? - Pyrosequencing Lagging strand polymerase: - Alpha In NGS what is coverage referring to - # of times a base is read Which type of NGS is best used for small indels? - paired-end Number of SNPs in human genome? - 10^7 book answer 10^6 exam answer (closest answer available) FLT3 is involved in what disease? - AML RNA storage condition for 6 months? - -70C in Ethanol How long to keep obsolete document in lab according to CAP? - 2 years HIV viral load difference? - 0.5 log 10 Antibiotic resistance mechanism in MRSA? - altered drug target PBP2a mecA What is the effect of Irinotecan and UGT1A1? - Decrease drug metabolism What part of RNA increases half-life and stability? - G cap or 5' cap Formamide decreases Tm by: - altering H-bonds Common form of DNA is: - B form, Right-Handed Order to add to a PCR reaction - Master mix