ADVANCED PHARMACOLOGY NSG 533 EXAM
EVALUATION QUESTIONS AND ANSWERS RATED A+
✔✔Roflumilast - ✔✔phosphodiesterase-4 inhibitor, may cause weight loss, diarrhea,
and depression
✔✔Intranasal decongestants - ✔✔oxymetazoline, phenylephrine, naphazoline
✔✔avoid intranasal decongestants with these conditions - ✔✔BPH, glaucoma, cardiac
disease, hyperthyroidism
✔✔Intranasal Cromolyn - ✔✔NasalCrom
Extremely safe but moderately effective
Suppresses release of histamines from mast cells
Best used for prophylaxis, not treatment
Response may take 1-2 wks to develop
✔✔how to treat hypertension - ✔✔a. Step 1: ACE inhibitor or ARB or CCB or thiazide
diuretic
b. Step 2: ACE inhibitor or ARB + CCB or thiazide diuretic
c. Step 3: ACE inhibitor or ARB + CCB + thiazide diuretic
Step 4: ACE inhibitor or ARB + CCB + thiazide diuretic + spironolactone
✔✔Avoid CCB in patients with - ✔✔heart failure or MI
✔✔avoid ARBs in patients with - ✔✔MI, pregnancy
✔✔Calcium Channel Blockers - ✔✔-dipine (dihydropyridine)
verapamil, diltiazem (non-dihydropyridines)
✔✔which CCB is best for angina - ✔✔verapamil
✔✔Contraindications for ACE inhibitors - ✔✔biliary renal artery stenosis, h/o
angioedema, pregnancy
✔✔contraindications for beta blockers - ✔✔asthma/ bronchospastic conditions, severe
bradycardia, AV block, bradycardia-tachycardia syndrome, severe unstable left
ventricular failure, edema, prizamental angina
do not use with verapamil, diltiazem, and digoxin
✔✔target digoxin level - ✔✔0.5-0.9 ng/mL
✔✔ARBS - ✔✔-sartan
EVALUATION QUESTIONS AND ANSWERS RATED A+
✔✔Roflumilast - ✔✔phosphodiesterase-4 inhibitor, may cause weight loss, diarrhea,
and depression
✔✔Intranasal decongestants - ✔✔oxymetazoline, phenylephrine, naphazoline
✔✔avoid intranasal decongestants with these conditions - ✔✔BPH, glaucoma, cardiac
disease, hyperthyroidism
✔✔Intranasal Cromolyn - ✔✔NasalCrom
Extremely safe but moderately effective
Suppresses release of histamines from mast cells
Best used for prophylaxis, not treatment
Response may take 1-2 wks to develop
✔✔how to treat hypertension - ✔✔a. Step 1: ACE inhibitor or ARB or CCB or thiazide
diuretic
b. Step 2: ACE inhibitor or ARB + CCB or thiazide diuretic
c. Step 3: ACE inhibitor or ARB + CCB + thiazide diuretic
Step 4: ACE inhibitor or ARB + CCB + thiazide diuretic + spironolactone
✔✔Avoid CCB in patients with - ✔✔heart failure or MI
✔✔avoid ARBs in patients with - ✔✔MI, pregnancy
✔✔Calcium Channel Blockers - ✔✔-dipine (dihydropyridine)
verapamil, diltiazem (non-dihydropyridines)
✔✔which CCB is best for angina - ✔✔verapamil
✔✔Contraindications for ACE inhibitors - ✔✔biliary renal artery stenosis, h/o
angioedema, pregnancy
✔✔contraindications for beta blockers - ✔✔asthma/ bronchospastic conditions, severe
bradycardia, AV block, bradycardia-tachycardia syndrome, severe unstable left
ventricular failure, edema, prizamental angina
do not use with verapamil, diltiazem, and digoxin
✔✔target digoxin level - ✔✔0.5-0.9 ng/mL
✔✔ARBS - ✔✔-sartan
