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NLN Pharmacology Practice Exam 2025/2026 – 75 High-Yield Questions | Dosage Calculations, Drug Side Effects, Antidotes, Pediatric & Geriatric Meds

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This expertly structured NLN Pharmacology Practice Exam for 2025/2026 includes 75 carefully selected questions with correct answers, targeting high-yield pharmacological concepts tested in NLN and nursing school assessments. Designed for rapid learning and clinical readiness, this resource focuses on essential drug knowledge, dosage calculations, administration safety, patient monitoring, and adverse reaction recognition. Topics covered include: medication administration math, IV flow rate problems, drug dosage conversions, side effects of antihypertensives, anticoagulants, insulin, antibiotics, opioids, corticosteroids, and psychotropics, as well as medication teaching points for various age groups (pediatrics to geriatrics). The guide highlights critical meds such as warfarin, vancomycin, digoxin, insulin types, ACE inhibitors, beta-blockers, nitrates, and chemotherapeutic agents. Also emphasized are lab values, nursing priorities, and patient safety protocols including Rhogam administration and safe injection practices. This document is especially useful for: NLN PAX (Pharmacology-focused) exam takers LPN, RN, ADN, and BSN nursing students Internationally trained nurses preparing for U.S. pharmacology exams Nursing tutors and NCLEX prep instructors Healthcare students in pharmacology-heavy programs such as Physician Assistant (PA) or Pre-Med Whether you're preparing for your nursing entrance exam, brushing up on med math, or reviewing before clinical rotations, this comprehensive pharmacology Q&A resource delivers concise, clinically relevant content to strengthen your test-taking skills and medication safety knowledge. Keywords: pharmacology questions, drug side effects, dosage calculations, IV rate, insulin types, medication teaching, warfarin precautions, vancomycin toxicity, drug math, Rhogam, pediatric dosage, adverse drug reactions, therapeutic levels, cardiac meds, respiratory meds, anticoagulants, chemotherapy safety, nursing pharmacology

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NLN Practice Pharm Exam 2025/2026
Exam Questions and Correct Answers |
New Update



A client who has renal failure has all of these prescriptions. Which on should a

nurse question? (single answer)

• Ampicillin sodium (omnipien-N)

• Calcitriol (Rocaltrol)

• Diphenhydramine hydrochloride (Benadryl)


• Tobramycin sulfate (Nebcin) - 🧠 ANSWER ✔✔d. Tobramycin sulfate (Nebcin)


A client has an order for 200 mg of cimetidine hydrochloride (Tagamet) IM. It is

supplied in a vial that contains 300 mg/2 mL. How many milliters should a nurse

administer to the client? (single answer)

• 0.6

,• 0.75

• 1.3


• 1.5 - 🧠 ANSWER ✔✔c. 1.3


A client is scheduled to start antibiotic therapy. Prior to administration of the initial

dose; a nurse should

• Ensure culture and sensitivity specimens have been obtained

• Obtain the client's body temperature

• Measure the client's urine output


• Determine the client's weight - 🧠 ANSWER ✔✔a. Ensure culture and sensitivity

specimens have been obtained

An 18-month-old child who weights 37 lb (17kg) has a temperature of 103 F (39.4

C). A physician orders acetaminophen (Tylenol) 15 mg/kg. How many milligrams

should a nurse administer?

• 120

• 148

• 200

, • 255 - 🧠 ANSWER ✔✔d. 255


A nurse is assessing a client who is taking glyburide (DiaBeta). Which of these

client manifestations who indicate the need for FURTHER assessment prior to

administering the scheduled dose of the medication?

• Cool, wet skin

• Elevated blood pressure

• Frequent urination


• Blurred vision - 🧠 ANSWER ✔✔a. Cool, wet skin


Which of these statements, if made by a client who is receiving warfarin sodium

(Coumadin), should indicate to a nurse that the client has a correct understanding

of the medication instructions?

• I will shave with an electric razor.

• I will increase my intake of green vegetables.

• I will use unwaxed dental floss twice daily.


• I will decrease my daily dose if I feel fatigued. - 🧠 ANSWER ✔✔a. I will shave

with an electric razor.




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