Answers | New Update
When did Wilhelm Roentgen discover x-rays? - Answer- November 8th, 1895
when did roentgen take an x-ray of his wife's hand? - Answer- December 22, 1895
who was the world's first radiation oncologist? - Answer- Emil Grubbe (1896)
what did emil grubbe use to treat a locally advances breast cancer? - Answer-
therapeutic use of x-rays
when was the first cancer cured? (basal cell carcinoma) - Answer- 1899
when did marie and pierre curie discover and isolate the first known radioactive
elements of polonium and radium - Answer- 1898
how was radiation first delivered? - Answer- in a few treatments
what was treatment length based on when radiation was first used to treat cancer? -
Answer- the amount of time it took for their skin to become erythemic
who found that treatment was better tolerated and more effective when treatment
consisted of smaller doses per day over several weeks? - Answer- claude regaud
what is the term used for claude's approach, and is the basis of most treatment today? -
Answer- fractionation
when did french radiation oncologist henri coutard pioneer the use of fractionation and
report impressive results? - Answer- 1934
limitation of treatment was lack of? - Answer- high energy, deeply penetrating beam
there was difficulty treating deep tumors without? - Answer- excessive skin reactions
instead, what would be placed close to or within the tumor? (brachytherapy) - Answer-
radioactive sources
What is radiation therapy? - Answer- the precise delivery of high-energy x-rays or other
forms of radiation to treat disease, especially cancer
radiation therapy may be used alone or in combination with? - Answer- surgery or
chemotherapy drugs
, what are the 2 uses of radiation therapy? - Answer- cure and palliation
how is radiation used to cure cancer? - Answer- - destroy tumors that have not spread
to other body parts
- reduce the risk that cancer will return after surgery of chemotherapy
how is radiation used to reduce symptoms? - Answer- - shrink tumors affecting quality
of life, like a lung tumor that is causing shortness of breath
- alleviate pain by reducing the size of a tumor
What is the goal of radiation therapy? - Answer- to maximize the dose to the tumor
while minimizing the dose to surrounding normal tissues
radiation should result in? - Answer- the eradication of the tumor and the preservation of
the function and visibility of the normal tissue
what is therapeutic ratio? - Answer- the difference between the dose for the probability
of tumor control and the dose that minimizes normal tissue damage
all cells are _______ equally sensitive to he effects of ionizing radiation - Answer- not
the cellular populations characterized as being most radiosensitive were first described
in? by? - Answer- 1906 by bergonie and tribondeau
what are the most radiosensitive cells? - Answer- cells that are rapidly dividing, poorly
differentiated and have a long mitotic period (ex: testicular and hodgkins)
radiation damages the genes in cancer cells causing them to? - Answer- die
Radiation first kills cells that are? - Answer- rapidly dividing
radiation delivered during external beam radiation is produced by a machine called? -
Answer- linear accelerator
what does a linear accelerator generate? - Answer- high energy radiation by
accelerating electrons to nearly the speed of light
the radiation produced by a linear accelerator in measured in? - Answer- millions of
volts
what are examples of kilovoltage equipment? - Answer- - grenz-ray therapy
- contact therapy
- superficial therapy
- orthovoltage therapy
what are examples of megavoltage equipment first used in 1937? - Answer- - cyclotron