NURS 615: ADVANCED
PHARMACOTHERAPEUTICS Maryville
university exam 4 questions with
100% correct answers
What is Tiotropium (SPIRIVA) used to treat? - ANSWER Used in the
management/ maintenance treatment of chronic obstructive pulmonary
disease (COPD) which includes chronic bronchitis and emphysema.
What is the drug classification of Tiotropium? - ANSWER >It is a long-
acting, 24H anticholinergic-bronchodilator.
>It is a muscurinic receptor antagonist, often referred to as an
antimuscurinic or anticholinergic agent.
What is the mechanism of action of Tiotropium (SPIRIVA) - ANSWER It
does not display selectivity for specific muscarinic receptors, when
topically applied it acts mainly on M3 muscarinic receptors[8] located on
smooth muscle cells and submucosal glands. Th is leads to a reduction in
smooth muscle contraction and mucus secretion and thus produces a
bronchodilatory effect.
What are the adverse effects with montelukast (Singular) - ANSWER
Anxiety, aggression, depression, suicidal thoughts,
, What patient teaching should accompany the prescription of
montelukast (Singulair)? - ANSWER Teach pt regarding adverse effect
about aggression , depression suicidal thoughts that could occur
What patient teaching should be provided when prescribing inhaled
corticosteroids? - ANSWER They should be taken 2x a day every day for
the use of prevention of asthma.
Rinse mouth after use to prevent oral thrush.
What ethnic background should not be prescribed long -acting beta
agonists? - ANSWER African Americans, increased incidence of death in
this population
What medication would you prescribe for bronchospasm for a patient
taking propranolol? - ANSWER Ipratropium
What is the mechanism of action of albuterol? - ANSWER Activation of
beta adrenergic receptors lead to relaxation of the muscle of the lung
and opening and dilation of the airway
Beta adrenergic receptor are coupled with stimulatory g -protein of the
the d-anelyl cyclase> This enzyme produces the second messennger
cyclic AMP (in the lungs it cAMP decreases calcium concentration w/in
cells and and activates protein kinase A. Both of these inactivates
myosin activase kinase and myosin like phosphatase
They open large conductants of hyperpolarize airway smooth muscle
cells
PHARMACOTHERAPEUTICS Maryville
university exam 4 questions with
100% correct answers
What is Tiotropium (SPIRIVA) used to treat? - ANSWER Used in the
management/ maintenance treatment of chronic obstructive pulmonary
disease (COPD) which includes chronic bronchitis and emphysema.
What is the drug classification of Tiotropium? - ANSWER >It is a long-
acting, 24H anticholinergic-bronchodilator.
>It is a muscurinic receptor antagonist, often referred to as an
antimuscurinic or anticholinergic agent.
What is the mechanism of action of Tiotropium (SPIRIVA) - ANSWER It
does not display selectivity for specific muscarinic receptors, when
topically applied it acts mainly on M3 muscarinic receptors[8] located on
smooth muscle cells and submucosal glands. Th is leads to a reduction in
smooth muscle contraction and mucus secretion and thus produces a
bronchodilatory effect.
What are the adverse effects with montelukast (Singular) - ANSWER
Anxiety, aggression, depression, suicidal thoughts,
, What patient teaching should accompany the prescription of
montelukast (Singulair)? - ANSWER Teach pt regarding adverse effect
about aggression , depression suicidal thoughts that could occur
What patient teaching should be provided when prescribing inhaled
corticosteroids? - ANSWER They should be taken 2x a day every day for
the use of prevention of asthma.
Rinse mouth after use to prevent oral thrush.
What ethnic background should not be prescribed long -acting beta
agonists? - ANSWER African Americans, increased incidence of death in
this population
What medication would you prescribe for bronchospasm for a patient
taking propranolol? - ANSWER Ipratropium
What is the mechanism of action of albuterol? - ANSWER Activation of
beta adrenergic receptors lead to relaxation of the muscle of the lung
and opening and dilation of the airway
Beta adrenergic receptor are coupled with stimulatory g -protein of the
the d-anelyl cyclase> This enzyme produces the second messennger
cyclic AMP (in the lungs it cAMP decreases calcium concentration w/in
cells and and activates protein kinase A. Both of these inactivates
myosin activase kinase and myosin like phosphatase
They open large conductants of hyperpolarize airway smooth muscle
cells
