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NR 546/ NR546 Final PRACTICE EXAM | Psychopharmacology | Questions and Answers | Latest 2025 /2026 Update | 100% Verified Elaborations | Graded A

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NR 546/ NR546 Final PRACTICE EXAM | Psychopharmacology | Questions and Answers | Latest 2025 /2026 Update | 100% Verified Elaborations | Graded A











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NR 546 Final PRACTICE EXAM |
Psychopharmacology | Questions and Answers | Latest
2025 /2026 Update | 100% Verified Elaborations |
Graded A


MAOIs (monoamine oxidase inhibitors) affect which neurotransmitters?

A. Serotonin, Dopamine, Norepinephrine
B. Serotonin, GABA, Glutamate
C. Acetylcholine, Dopamine, Norepinephrine
D. Dopamine, GABA, Acetylcholine

A. Serotonin, Dopamine, Norepinephrine

Which of the following is considered first line treatment for depression?

A. SSRI
B. FGA
C. SNRI
D. MAOI

A. SSRI

When treating a patient for major depression disorder which medication would the
PMHNP consider first?

A. Depakote
B. Selegiline
C. Escitalopram
D. Isocarboxazid

C. Escitalopram

,Which of the following medication should be considered for a patient diagnosed
with major depressive disorder who reports "always forgetting to take my pills"?

A. Mirtazapine
B. Fluvoxamine
C. Fluoxetine
D. Carbemazepine

C. Fluoxetine



Which of the following medication has a black box warning of a life-threatening
skin rash?

A. Lithium
B. Lamotrigine
C. Lurasidone
D. Lorazepam

B. Lamotrigine

Which medication is considered the best tolerated SSRI?

A. Venlafaxine
B. Bupropion
C. Setraline
D. Escitalopram

D. Escitalopram

During a 4 week follow up appointment, Rashida, who is prescribed Sertraline
25mg qAM reports slight improvement in depression symptoms and tolerating
medication well. Which of the following should the PMHNP do?

A. Increase Setraline dose
B. Switch to an SNRI
C. Switch to a different SSRI
D. Add Trazodone qHS for sleep.

A. Increase Setraline dose

, Which medication should be avoided for the 66 year patient diagnosed with major
depressive disorder and anxiety with a reported fall 3 months ago?

A. Citalopram
B. Setraline
C. Paroxetine
D. Aripiprazole

C. Paroxetine

A patient reports upset stomach and diarrhea 3 days after taking new prescription
of sertraline. Which of the following is the most appropriate response from the
PMHNP?

A. "Start doubling the dose of sertraline and your symptoms will begin to ease up".
B. "Most side effects subside after 4-5 days. Your body is getting adjusted to the
increased serotonin levels".
C. "Stop taking it immediately and go to the local emergency department".
D. "You must take Sertraline with food, otherwise you will continue to experience
GI symptoms".

B. "Most side effects subside after 4-5 days. Your body is getting adjusted to the
increased serotonin levels".

During a 2 week follow up appointment, the patient reports no improvement in
depressive symptoms with escitalopram. Which of the following statement made
by the PMHNP is correct?

A. "Let's discontinue escitalopram and start you on something stronger".
B. "It can take up to 6 weeks before you notice improvements of depressive
symptoms".
C. "I am going to prescibe Trazodone. Take it at night to help you sleep".
D. "Start taking two pills at a time".

B. "It can take up to 6 weeks before you notice improvements of depressive
symptoms".

Duloxetine effects which two neurotransmitters?

A. serotonin and norepinephrine
B. serotonin and dopamine

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