GMS 6540 CORE EXAM SET 2025/2026 QUESTIONS WITH SOLUTIONS RATED A+

GMS 6540 CORE EXAM SET 2025/2026 QUESTIONS
WITH SOLUTIONS RATED A+
✔✔In what location does Cetuximab bind EGFR?

Extracellularly
Intramembranously
Intracellularly
Intranuclearly - ✔✔Extracellularly

✔✔Which type of immune cells induce ADCC in cells treated with Cetuximab?

B cells
Plasma cells
Granulocytes
Natural killer cells
Monocytes - ✔✔Natural killer cells

✔✔If a patient is being treated with Osimertinib, what were they likely treated with
previously?

Cetuximab
Erlotinib
Trastuzumab
Lapatinib
Imatinib - ✔✔Erlotinib

✔✔What is the endogenous ligand for HER2?

EGF
Neu
PDGF
HGF
It has no known ligand. - ✔✔It has no known ligand.

✔✔A breast cancer patient with a tumor with which characterization would be most
likely to respond to Tamoxifen?

ER- PR+ HER2+
ER- PR+ HER2-
ER- PR- HER2-
ER+ PR+ HER2+
ER+ PR- HER2- - ✔✔ER+ PR- HER2-

✔✔Which class of drugs could potentially increase estrogen signaling?

, SERMs
SERDs
AIs - ✔✔SERMs

✔✔Which drug significantly increases the risk of DVTs?

Tamoxifen
Raloxifene
Fulvestrant
Anastrozole
Exemastane - ✔✔Raloxifene

✔✔Which drug is given intramuscularly?

Tamoxifen
Raloxifene
Fulvestrant
Anastrozole
Exemastane - ✔✔Fulvestrant

✔✔Enzalutamide blocks the signaling caused by which hormone?

Testosterone
Estrogen
Progestin
TSH
FSH - ✔✔Testosterone

✔✔Do x-rays have shorter or longer wavelengths than visible light?

Shorter
Longer - ✔✔Shorter

✔✔Most DNA damage caused during x-ray radiation therapy is ______.

Direct
Indirect - ✔✔Indirect

✔✔Pieces of Iodine-125 are sometimes placed in the prostate to treat prostate cancer.
This type of treatment is called.

Teletherapy
External beam therapy
Proton therapy