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WGU Pharmacology D116 (2024/25) – 150+ Practice Questions & Correct Answers – CNS, Cardio, Psych, Endocrine, Infectious Disease, & More

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This expertly structured document contains over 150 carefully verified pharmacology practice questions and answers designed specifically for the Western Governors University (WGU) D116 Pharmacology course in the 2024/25 academic year. It comprehensively covers key pharmacological principles and clinical applications in areas including central nervous system (CNS) drugs, cardiovascular medications, psychiatric pharmacotherapy, endocrine treatments, infectious disease agents, respiratory medications, reproductive health drugs, gastrointestinal agents, and more. Each question is presented in a clear clinical scenario format and is paired with a verified and graded A+ answer, along with brief explanations and rationales that support deep understanding. The document also includes content on polypharmacy, medication reconciliation, black box warnings, vitamin and supplement use, and special considerations in pregnancy and geriatrics, making it highly practical for real-world nursing and advanced clinical practice. This resource is highly valuable for: Nursing students enrolled in WGU’s prelicensure and RN-to-BSN programs APRNs (Advanced Practice Registered Nurses) Students preparing for pharmacology certification exams (e.g., NCLEX, NP board exams) Learners in pharmacy technician training, health sciences, or allied health programs Whether you're studying for assessments, preparing for clinical rotations, or reviewing for certification, this document provides high-yield, exam-relevant material to support academic success and professional readiness. Keywords: pharmacology, WGU, D116, practice questions, CNS drugs, cardiovascular medications, psychiatric drugs, endocrine system, infectious diseases, respiratory medications, reproductive health, gastrointestinal agents, NCLEX prep, nursing pharmacology, medication safety, polypharmacy, APRN, drug mechanisms, side effects, black box warnings

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2024/25|WGU D116 Pharmacology
||2024-2025 Most Recent
Version|Comprehensive Questions and
Verified Answers/Accurate
Solutions|Already Graded A+|Get it
100% Correct.

A patient presents to an emergency room complaining of palpitations and irregular

heartbeat. The advanced practice registered nurse (APRN) places the patient on a

cardiac monitor and observes atrial fibrillation. The APRN orders dofetilide.

How should the APRN recommend this medication be taken? - 🧠 ANSWER

✔✔YES With food or an empty stomach


A 70-year-old male calls a clinic complaining of chest pain that started after having

sexual activity. He took sildenafil 50 mg about eight hours ago. He has

nitroglycerin 0.3 mg on hand.


How should the advanced practice registered nurse respond? - 🧠 ANSWER ✔✔Do

not take the nitroglycerin and call 911

,Taking the medications together can cause a serious drop in blood pressure leading

to cardiovascular collapse.

A patient diagnosed with bipolar disorder who is in a mental health clinic is

discussing the possibility of beginning lithium with an advanced practice registered

nurse (APRN). The patient expresses understanding and wishes to proceed with

treatment. The APRN explains to the patient that this medication requires specific

lab monitoring and wants to draw baseline labs. The patient asks why the test is

needed.


Which explanation should the APRN provide to this patient? - 🧠 ANSWER ✔✔A

baseline blood urea nitrogen (BUN) and creatinine (CREA) level needs to be

drawn to assess kidney function prior to treatment.




This drug can cause decreased renal function, and a baseline should be drawn for

future comparison.

An advanced practice registered nurse (APRN) is reviewing the medications that

will be commonly experienced with a new nurse to determine whether the drugs




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,are safe for the patients. The new nurse is given a scenario where a patient is being

prescribed sildenafil 25 mg po prn, a prototype drug for erectile dysfunction.


Which patient may take this drug safely? - 🧠 ANSWER ✔✔YES A 54-year-male

with a medical history of hypertension, mild eczema, and previous history of a

urolithiasis where all is well controlled and there are no current complications

A 30-year-old patient presents to a primary care clinic with a history of anxiety.

The advanced practice registered nurse reviews the mechanism of action by which

many neuropharmacological agents act and decides to prescribe citalopram.


What is the mechanism of action of this medication? - 🧠 ANSWER ✔✔YES

Influences receptor activity on target cells




Correct! This medication influences the activity in the receptors, and it targets

cells.

A patient is admitted with a diagnosis of Huntington disease. On admission, the

patient exhibits uncontrolled twitching, difficulty walking, trouble swallowing,

confusion, and memory loss. The advanced practice registered nurse (APRN)

prescribes baclofen.




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, What is the mechanism of action of this medication? - 🧠 ANSWER ✔✔NO

Modulates the effects of glutamate at NMDA receptors

YES Inhibits neurotransmitter GABA

NO Halts the breakdown of acetylcholine by acetylcholinesterase

Alters the synthesis and release of norepinephrine, serotonin, and dopamine

Incorrect. Cholinesterase inhibitors prevent the breakdown of acetylcholine by

acetylcholinesterase. They are used in patients with Alzheimer's.

Correct! Huntington's disease involves a deficiency of the neurotransmitters

acetylcholine and y-aminobutyric acid in the basal ganglia and extrapyramidal

system.

A 21-year-old patient accompanied by a parent comes to a clinic for an emergency

visit with an advanced practice registered nurse (APRN) following a seizure. Upon

interviewing the patient and the parent, the APRN determines that the seizure is

classified by marked impairment of consciousness and is followed by a period of

central nervous system (CNS) depression.


Which type of seizure is this patient experiencing? - 🧠 ANSWER ✔✔Atonic


NO Myoclonic

YES Tonic-clonic

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