MICROBIAL PATHOGENESIS - ATYPICAL BACTERIA: MYCOBACTERIUM, SPIROCHETES, OBLIGATE INTRACELLULAR PARASITES (100% VERIFIED REVIEW SOLUTION Q&A 2025) What are some general characteristics of Mycobacterium? - ANS-Obligate aerobes - slow growing (takes weeks or months to culture) - unique, thick waxy cell wall = acid fast - facultatively intracellular (grow in or out of cell) What is present in the cell wall of mycobacterium? Why is it important? - ANS-mycolic acid - resistant to drying How does slow mycobacterium growth impact antibiotic treatment? - ANS-need to take for 6 months to 1 year - antibiotics target dividing bacteria (need to ensure all bacteria had a chance to divide) What 2 species of mycobacterium cause disease in humans? - ANS-1) Mycobacterium tuberculosis 2) Mycobacterium leprae What are 5 common disease symptoms associated with M.tuberculosis? - ANS-Progressive weight loss (wasting), persistent cough (often w/ blood), pneumonia, night sweats, organ failure T/F: M.leprae can only be grown in vitro in armadillos - ANS- Continues...
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