D027 PRACTICE TEST LATEST 2025 QUESTIONS
AND ANSWERS ALREADY AWARDED A+
A patient has endured several dosage adjustments of his tricyclic
antidepressant, so the provider recommends genetic testing. Which statement
correctly describes the rationale for genetic testing?
a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and
certain other drugs.
b. The HER2 gene is a tumor marker that impacts metabolism of tricyclic
antidepressants.
c. The BRCA2 gene influences metabolism of certain drugs and increases the risk
for breast cancer.
d. The x linked OPN1MW gene for male color blindness also slows metabolism
of certain - CORRECT ANSWER-a. The CYP2D6 gene influences metabolism of
tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene
that codes for color blindness in men. Metabolism of 25% of all prescribed
drugs, including tricyclic antidepressants, beta adrenergic receptor blockers, and
neuroleptics, is influenced by variants in a certain gene, requiring genetic testing
to reduce trial-and-error in estimating appropriate drug-dosage levels.
1
,According to the Centers for Disease Control and Prevention, the 10 most costly
chronic conditions include cardiovascular diseases, obesity, asthma, diabetes,
smoking and alcohol related conditions, cancer, Alzheimer's disease, arthritis
and stroke. Which are the top 4 in ranking from most costly to least costly?
a. Cardiovascular diseases, obesity, diabetes, cancer
b. Cardiovascular diseases, diabetes, obesity, cancer
c. Cardiovascular diseases, Smoking-related conditions, Alcohol-related
conditions, diabetes
d. Cardiovascular diseases, Stroke, Obesity, Diabetes - CORRECT ANSWER-c.
Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions,
diabetes
A mother brought her child to the doctor for genetic testing. The health care
provider was trying to explain the genetic results of the child. During his
explanation he tells the mother that the child has 2 X chromosomes and a Y
chromosome in each cell. He begins to explain some physical appearances the
mother might notice on her son. He explains that she might notice that he has
sparse body hair, long limbs and small testes. The health care practitioner is
explaining which syndrome to the mother.
a. Klinefelter syndrome
b. Turners' syndrome
c. Down syndrome
d. Kawasaki's disease - CORRECT ANSWER-a. Klinefelter syndrome
2
, Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y
chromosome in each cell. Because of the Y chromosome these individuals have
a male appearance, but they are usually sterile and about half develop female-
like breasts.
A patient reports a maternal family history of Lynch syndrome. Which laboratory
finding might indicate a need for further testing for the presence of Lynch
syndrome in this patient?
a. Elevated thyroid-stimulating hormone
b. Low cortisol level
c. Positive heme-occult test
d. Sputum positive for Pseudomonas Aeruginosa - CORRECT ANSWER-a. Positive
heme-occult test
Positive heme-occult because Lynch syndrome is a hereditary form of colorectal
cancer and colorectal bleeding can be a sign of cancer
An individual's acquired immunity is dependent on the function of which cells?
(Select all that apply.)
a. B lymphocytes
b. Opsonins
c. T lymphocytes
d. Macrophages - CORRECT ANSWER-a. B lymphocytes
c. T lymphocytes
3
AND ANSWERS ALREADY AWARDED A+
A patient has endured several dosage adjustments of his tricyclic
antidepressant, so the provider recommends genetic testing. Which statement
correctly describes the rationale for genetic testing?
a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and
certain other drugs.
b. The HER2 gene is a tumor marker that impacts metabolism of tricyclic
antidepressants.
c. The BRCA2 gene influences metabolism of certain drugs and increases the risk
for breast cancer.
d. The x linked OPN1MW gene for male color blindness also slows metabolism
of certain - CORRECT ANSWER-a. The CYP2D6 gene influences metabolism of
tricyclic antidepressants and certain other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene
that codes for color blindness in men. Metabolism of 25% of all prescribed
drugs, including tricyclic antidepressants, beta adrenergic receptor blockers, and
neuroleptics, is influenced by variants in a certain gene, requiring genetic testing
to reduce trial-and-error in estimating appropriate drug-dosage levels.
1
,According to the Centers for Disease Control and Prevention, the 10 most costly
chronic conditions include cardiovascular diseases, obesity, asthma, diabetes,
smoking and alcohol related conditions, cancer, Alzheimer's disease, arthritis
and stroke. Which are the top 4 in ranking from most costly to least costly?
a. Cardiovascular diseases, obesity, diabetes, cancer
b. Cardiovascular diseases, diabetes, obesity, cancer
c. Cardiovascular diseases, Smoking-related conditions, Alcohol-related
conditions, diabetes
d. Cardiovascular diseases, Stroke, Obesity, Diabetes - CORRECT ANSWER-c.
Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions,
diabetes
A mother brought her child to the doctor for genetic testing. The health care
provider was trying to explain the genetic results of the child. During his
explanation he tells the mother that the child has 2 X chromosomes and a Y
chromosome in each cell. He begins to explain some physical appearances the
mother might notice on her son. He explains that she might notice that he has
sparse body hair, long limbs and small testes. The health care practitioner is
explaining which syndrome to the mother.
a. Klinefelter syndrome
b. Turners' syndrome
c. Down syndrome
d. Kawasaki's disease - CORRECT ANSWER-a. Klinefelter syndrome
2
, Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y
chromosome in each cell. Because of the Y chromosome these individuals have
a male appearance, but they are usually sterile and about half develop female-
like breasts.
A patient reports a maternal family history of Lynch syndrome. Which laboratory
finding might indicate a need for further testing for the presence of Lynch
syndrome in this patient?
a. Elevated thyroid-stimulating hormone
b. Low cortisol level
c. Positive heme-occult test
d. Sputum positive for Pseudomonas Aeruginosa - CORRECT ANSWER-a. Positive
heme-occult test
Positive heme-occult because Lynch syndrome is a hereditary form of colorectal
cancer and colorectal bleeding can be a sign of cancer
An individual's acquired immunity is dependent on the function of which cells?
(Select all that apply.)
a. B lymphocytes
b. Opsonins
c. T lymphocytes
d. Macrophages - CORRECT ANSWER-a. B lymphocytes
c. T lymphocytes
3
