2025\2026
NSG 100 Exam #3 Review
Questions and answers
2025/2026 latest update
USER
STUVIA
,What is the study of physiochemical properties of drugs and how they influence the body called?
A.Pharmaceutics
B.Pharmacokinetics
C.Pharmacodynamics
D.Pharmacotherapeutics -✔✔ answer ANS: C
Pharmacodynamics: The study of what the drug does to the body. The study of the biochemical and
physiologic interactions of drugs at their sites of activity. It examines the effect of the drug on the body.
(Lilley, 2020 p. 14)
Pharmacokinetics: The study of what the body does to the drug. The study of what happens to a drug
from the time it is put into the body until the parent drug and all metabolites have left the body.
Pharmacokinetics represent the drug absorption into, distribution and metabolism within, and excretion
from the body. (Lilley, 2020 p. 14)
Pharmacotherapeutics: The treatment of pathologic conditions through the use of drugs. (Lilley, 2020 p.
14)
Pharmaceutics The science of preparing and dispensing drugs, including dosage form design. (Lilley,
2020 p. 14) The study of how various drug forms influence the way in which the drug affects the body.
(Lilley, 2020 p. 16
A patient asks the nurse the difference between a generic drug and a trade or brand-name drug. Which
of the following are true regarding generic drugs? (Select all that apply)
A.Have less potential for abuse and dependence
B.Have the same chemical composition as the brand-name drug
C.May have several brand names
D.May have several generic names
E.Are usually less expensive than a brand-name drug -✔✔ answer Answer: B, C, E
Generic and trade or brand-name drugs have the same chemical composition and the same effects,
Generic drugs are usually less expensive. Each drug has only one generic name. The trade name is the
brand of proprietary name given by the manufacturer; various manufacturers give the drug different
brand names. There is no difference in abuse potential between a generic and brand-name drug.
Patients with renal failure would most likely have problems with which pharmacokinetic process?
A.Excretion
, B.Absorption
C.Metabolism
D.Distribution -✔✔ answer ANS: A
The kidneys are responsible for the majority of drug excretion. A patient with renal failure would have a
difficult time with drug excretion.
A staff educator is preparing an in-service to review factors that influence medication metabolism.
Which of the following would the educator include as a reason to administer a lower medication
dosage? (Select all that apply)
A.Increased renal excretion
B.Increased medication-metabolizing enzymes
C.Liver failure
D.Peripheral vascular disease
E.Concurrent use of medication with the same pathway of metabolism -✔✔ answer Answer: C, E
Rationale: Increased renal excretion and Increased medication-metabolizing enzymes decrease the
concentration of the medication, potentially requiring increased strength. Liver failure decreases
metabolism, thus increasing the concentration of a medication. This requires decreasing the dosage.
Peripheral vascular disease impairs distribution, may require an increased dose. When the same
pathway metabolizes two medications, they compete for metabolism, potentially increasing the
concentration of one or both medications. Requiring deceasing the dose of one or both medications
A patient asks the nurse why a lower dose of IV pain medication is being given than the previous oral
dose. What is the nurse's best response to the patient?
A."Medications given orally bypass the portal circulatory system."
B."Medications given intravenously are not affected by the first-pass effect."
C."Drugs administered intravenously enter the portal system before systemic distribution."
D."A large percentage of an intravenously administered drug is metabolized into inactive metabolites in
the liver." -✔✔ answer Ans: B
Rationale: When drugs with a high first-pass effect are administered orally, a large amount of drug may
be metabolized before it reaches the systemic circulation. The same drug given IV will bypass the liver.
This prevents the first-pass effect from taking place, and therefore more of the drug reaches the
circulation. Parenteral doses of drugs with a high first-pass effect are much smaller than oral doses, yet
they produce the same pharmacologic response.
NSG 100 Exam #3 Review
Questions and answers
2025/2026 latest update
USER
STUVIA
,What is the study of physiochemical properties of drugs and how they influence the body called?
A.Pharmaceutics
B.Pharmacokinetics
C.Pharmacodynamics
D.Pharmacotherapeutics -✔✔ answer ANS: C
Pharmacodynamics: The study of what the drug does to the body. The study of the biochemical and
physiologic interactions of drugs at their sites of activity. It examines the effect of the drug on the body.
(Lilley, 2020 p. 14)
Pharmacokinetics: The study of what the body does to the drug. The study of what happens to a drug
from the time it is put into the body until the parent drug and all metabolites have left the body.
Pharmacokinetics represent the drug absorption into, distribution and metabolism within, and excretion
from the body. (Lilley, 2020 p. 14)
Pharmacotherapeutics: The treatment of pathologic conditions through the use of drugs. (Lilley, 2020 p.
14)
Pharmaceutics The science of preparing and dispensing drugs, including dosage form design. (Lilley,
2020 p. 14) The study of how various drug forms influence the way in which the drug affects the body.
(Lilley, 2020 p. 16
A patient asks the nurse the difference between a generic drug and a trade or brand-name drug. Which
of the following are true regarding generic drugs? (Select all that apply)
A.Have less potential for abuse and dependence
B.Have the same chemical composition as the brand-name drug
C.May have several brand names
D.May have several generic names
E.Are usually less expensive than a brand-name drug -✔✔ answer Answer: B, C, E
Generic and trade or brand-name drugs have the same chemical composition and the same effects,
Generic drugs are usually less expensive. Each drug has only one generic name. The trade name is the
brand of proprietary name given by the manufacturer; various manufacturers give the drug different
brand names. There is no difference in abuse potential between a generic and brand-name drug.
Patients with renal failure would most likely have problems with which pharmacokinetic process?
A.Excretion
, B.Absorption
C.Metabolism
D.Distribution -✔✔ answer ANS: A
The kidneys are responsible for the majority of drug excretion. A patient with renal failure would have a
difficult time with drug excretion.
A staff educator is preparing an in-service to review factors that influence medication metabolism.
Which of the following would the educator include as a reason to administer a lower medication
dosage? (Select all that apply)
A.Increased renal excretion
B.Increased medication-metabolizing enzymes
C.Liver failure
D.Peripheral vascular disease
E.Concurrent use of medication with the same pathway of metabolism -✔✔ answer Answer: C, E
Rationale: Increased renal excretion and Increased medication-metabolizing enzymes decrease the
concentration of the medication, potentially requiring increased strength. Liver failure decreases
metabolism, thus increasing the concentration of a medication. This requires decreasing the dosage.
Peripheral vascular disease impairs distribution, may require an increased dose. When the same
pathway metabolizes two medications, they compete for metabolism, potentially increasing the
concentration of one or both medications. Requiring deceasing the dose of one or both medications
A patient asks the nurse why a lower dose of IV pain medication is being given than the previous oral
dose. What is the nurse's best response to the patient?
A."Medications given orally bypass the portal circulatory system."
B."Medications given intravenously are not affected by the first-pass effect."
C."Drugs administered intravenously enter the portal system before systemic distribution."
D."A large percentage of an intravenously administered drug is metabolized into inactive metabolites in
the liver." -✔✔ answer Ans: B
Rationale: When drugs with a high first-pass effect are administered orally, a large amount of drug may
be metabolized before it reaches the systemic circulation. The same drug given IV will bypass the liver.
This prevents the first-pass effect from taking place, and therefore more of the drug reaches the
circulation. Parenteral doses of drugs with a high first-pass effect are much smaller than oral doses, yet
they produce the same pharmacologic response.
