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NR 511 Diferential Diagnosis and Primary Care- Mid Term Review

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NR 511 Diferential Diagnosis and Primary Care- Mid Term Review

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NRnj511njDifferentialnjDiagnosisnjandnjPrimarynjCare-
nj Midnj Termnj Review


1.whatnjisnjthenjsensitivitynjofnjthenjProstatenjSpecificnjAntigennj(PSA)njfornjdetecti
ngnjprostatenjcancer?:nj#njmennjwithnjprostatenjcancer
#njmennjwithnjpositivenjPS
Anj160

#njmennjwithnjnegativenjP
SAnj40

tot
alnj2
00

Thenjcorrectnjanswernjisnj160/200.njSensitivitynjisnjthenjproportionnjofnjpatientsn
withnjthenjdiseasenjthatnjhavenjanjpositivenjresult;njitnjisnjthenjnumbernjofnjtruenjpo
sitivesnjdividednjbynjthenjtotalnjnumbernjofnjpatientsnjwhonjhavenjthenjdisease.
2.Anjdiagnosticnjtestnjisnjusednjinnjanjsamplenjofnj1000njpatients.nj500njofnjthesenjpatie
ntsnjhavenjthenjdisease,njwhilenj500njdonjnot.njOfnjthosenj500njpatientsnjwithoutnjthenjd
isease,nj30njtestnjpositive,njandnj470njtestnjnegative.njWhatnjisnjthenjspecificitynjofnjthe
njtest?:njThenjcorrectnjanswernjisnj470/500.




Specificitynjisnjthenjproportionnjofnjpatientsnjwhonjtestnjnegativenjoutnjofnjthenjt
otalnjnumbernjofnjpatientsnjwhonjdonjnotnjhavenjthenjdisease;njitnjisnjthenjnumbe
rnjofnjtruenjnegativesnjoverallnjnegatives.njInnjthisnjexample,nj500/1000njpatie
ntsnjhavenjthenjdisease.njOfnjthosenj500njpatientsnjwithoutnjthenjdisease,nj30njt
estnjpositive,njandnj470njtestnjnegative.
3.ThenjPositivenjPredictivenjValuenj(PPV)njofnjanjtestnjrefersnjtonjwhichnjofnjthenjfoll
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njing?:njthenjproportionnjofnjpatients njwithnjanjpositivenjtestnjwhonjhavenjthenjdi

sease.
4.Whichnjofnjthenjfollowingnjdependsnjonnjthenjprevalencenjofnjthenjdisease?:njposi
tivenjpredictivenjvalue.

Predictivenjvaluesnjdependnjonnjthenjprevalencenjofnjdiseasenjinnjthenjpopulati
onnjwhereasnjsensitivitynjandnjspecificitynjarenjintrinsicnjpropertiesnjofnjthenjte
st.njReliabilitynjrefersnjtonjthenjconsistencynjornjstabilitynjofnjanjmeasure.
5.Anjlownjpretestnjprobabilitynjofnjdiseasenjmaynjleadnjtonjwhichnjofnjthenjfollowing?:nj
lownjpositivenjpredictivenjvaluenjandnjmorenjfalse-positivenjresults.

Positivenjpredictivenjvaluenjincreasesnjwithnjprevalence;njtherefore,njanjlownjpr
1nj/
nj48

, NRnj511njDifferentialnjDiagnosisnjandnjPrimarynjCare-
nj Midnj Termnj Review

evalencenjvaluenjyieldsnjanjlownjpositivenjpredictivenjvaluenjandnjimpliesnjanjhig
hnjfalse-
positivenjrate.njNegativenjpredictivenjvaluenjdecreasesnjwithnjprevalence,njand
njsensitivitynjandnjspecificity njdonjnotnjvarynjwithnjprevalence.




2nj/
nj48

, NRnj511njDifferentialnjDiagnosisnjandnjPrimarynjCare-
nj Midnj Termnj Review


6.Ifnjyounjstronglynjsuspectnjthatnjanjpatientnjisnjpositivenjfornjanjspecificnjconditionnj
butnjtestsnjnegative,njthenjnegativenjresultnjmaynjbe::njfalse-
negativenjtestnjresultsnjduenjtonjanjlownjnegativenjpredictivenjvalue.

Atnjthenjindividualnjlevel,njyournjclinicalnjsuspicionnjisnjequivalentnjtonjpre-
testnjprobabilitynjandnjhighnjprevalencenjatnjthenjpopulationnjlevel.njNegativenjp
redictivenjvaluenjisnjinverselynjcorrelatednjwithnjprevalence;njtherefore,njyournj
clinicalnjsuspicionnjtranslatesnjtonjanjlownjnegativenjpredictivenjvalue,njsuggest
ingnjanjfalse-negativenjtestnjresult.
7.Whichnjtest(s)njprovidenjdatanjrelevantnjtonjthenjchiefnjcomplaint:njFever:njCBC

ChecknjCBCnjwithnjdifferentialnjfornjneutrophilnjshiftnjinnjsuspectednjinfection
8.Whichnjtest(s)njprovidenjdatanjrelevantnjtonjthenjchiefnjcomplaint:njUnexplain
ednjbruising:njCBC

Checknjplateletnjcount
9.Whichnjtest(s)njprovidenjdatanjrelevantnjtonjthenjchiefnjcomplaint:njFatigue:njBothnj
CBCnjandnjCMP

ChecknjRBC,njHgbnjandnjHctnjfornjanemia,njCMPnjfornjpotentialnjlivernjornjkidneynjab
ormalities
10.Whichnjtest(s)njprovidenjdatanjrelevantnjtonjthenjchiefnjcomplaint:njCardiacnjd
ys-njrhythmias:njCMP

Monitornjelectrolytesnjfornjabnormalities
11.Whichnjtest(s)njprovidenjdatanjrelevantnjtonjthenjchiefnjcomplaint:njUnexplain
ednjweightnjloss:njBothnjCBCnjandnjCMP

ChecknjWBCnjfornjinflammationnjornjpossiblenjcancer,njCMPnjfornjglucose,njlivernj
ornjkidneynjabnormalities
12.Whichnjtest(s)njprovidenjdatanjrelevantnjtonjthenjchiefnjcomplaint:njEdema:njCMP

Checknjfornjkidneynjfunction
13.WhatnjisnjSNAPPS?:njSummarizenjthenjhistorynjandnjfi
ndingsnjNarrownjthenjdifferentialnjdiagnosisnjtonjtwonjornjt
hreenjpossibilities
Analyzenjthenjdifferentialnjbynjcomparingnjandnjcontrastingnjthenjp
ossibilitiesnjProbenjthenjpreceptornjbynjaskingnjquestionsnjaboutnjal ornjuncertai
ternativenjapproachesnjties n-
3nj/
nj48

, NRnj511njDifferentialnjDiagnosisnjandnjPrimarynjCare-
nj Midnj Termnj Review

Plannjthenjmanagementnjofnjthenjclient'snjhealthnjiss
uesnjSelectnjannjissuenjfromnjthenjcasenjfornjself-
directednjlearning




4nj/
nj48

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