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ONS Chemotherapy Immunotherapy
Certificate Questions with Detailed
Verified Answers
Question:Define neoadjuvant therapy
Ans: Treatment is given prior to surgery to shrink the tumor
Question: Define adjuvant therapy
Ans: Additional cancer treatment given after the primary treatment to lower
the risk that the cancer reoccur
Question: 3 subcategories of alkylating agents:
Ans: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
Question: Common alkylating agents:
Ans: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Question: Common platinum-based agents:
Ans: Cisplatin (Platinol)
Carboplatin (Paraplatin)
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Question: What is unique about nitrosoureas agents?
Ans: Able to cross the blood-brain barrier; can be effective in treating some
brain tumors
Question: Common nitrosoureas agents:
Ans: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Question: Hypersensitivity can occur with late doses of:
Ans: Carboplatin
Question: These agents are typically categorized as highly emetogenic:
Ans: 1. Alkylating agents
2. Nitrosoureas
Question: Pre-administration labs for alkylating agents and nitrosoureas:
Ans: BUN
Creatinine
CBC w/ diff
Question: What is the medication Mesna used for?
Ans: Bladder protectant with administration of cyclophosphamide or
ifosfamide
Question: Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment
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Ans: Oxaliplatin
Question: How do antimetabolites function?
Ans: By blocking DNA and RNA growth by interfering with enzymes needed
for normal cell metabolism
Question: Antimetabolites work in the ___ phase.
Ans: S
Question: Common side effects of antimetabolites:
Ans: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Question: Common antimetabolite drugs:
Ans: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
Question: The institute for Safe Medication Practices recommends what
route of administration for vincristine?
Ans: IV piggyback via gravity
ONS Chemotherapy Immunotherapy
Certificate Questions with Detailed
Verified Answers
Question:Define neoadjuvant therapy
Ans: Treatment is given prior to surgery to shrink the tumor
Question: Define adjuvant therapy
Ans: Additional cancer treatment given after the primary treatment to lower
the risk that the cancer reoccur
Question: 3 subcategories of alkylating agents:
Ans: 1. Nitrogen mustards
2. Platinum-based agents (do not possess an alkyl group but still termed
alkylating agents as they work similarly)
3. Nitrosoureas
Question: Common alkylating agents:
Ans: Cyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Question: Common platinum-based agents:
Ans: Cisplatin (Platinol)
Carboplatin (Paraplatin)
, Page | 2
Question: What is unique about nitrosoureas agents?
Ans: Able to cross the blood-brain barrier; can be effective in treating some
brain tumors
Question: Common nitrosoureas agents:
Ans: Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Question: Hypersensitivity can occur with late doses of:
Ans: Carboplatin
Question: These agents are typically categorized as highly emetogenic:
Ans: 1. Alkylating agents
2. Nitrosoureas
Question: Pre-administration labs for alkylating agents and nitrosoureas:
Ans: BUN
Creatinine
CBC w/ diff
Question: What is the medication Mesna used for?
Ans: Bladder protectant with administration of cyclophosphamide or
ifosfamide
Question: Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment
, Page | 3
Ans: Oxaliplatin
Question: How do antimetabolites function?
Ans: By blocking DNA and RNA growth by interfering with enzymes needed
for normal cell metabolism
Question: Antimetabolites work in the ___ phase.
Ans: S
Question: Common side effects of antimetabolites:
Ans: Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Question: Common antimetabolite drugs:
Ans: Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
Question: The institute for Safe Medication Practices recommends what
route of administration for vincristine?
Ans: IV piggyback via gravity
