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Exam (elaborations)

ONS/ONCC Chemotherapy Immunotherapy Certificate Questions with Detailed Verified Answers

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ONS/ONCC Chemotherapy Immunotherapy Certificate Questions with Detailed Verified Answers

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ONS/ONCC Chemotherapy
Immunotherapy Certificate Questions
with Detailed Verified Answers

Question:Lesson 1: Foundations to Set the Stage

Ans:

Question: Focusing on Cellular Structure and Function

Ans:

Question: The Normal Cell Cycle

Ans: -The cell cycle refers to the ordered seres of processes of DNA replication
and mitosis, or cell division




-Cell nucleus regulates these processes by gathering and processing
complexes molecular information

Question: Interphase and Mitotic Phase

Ans: Cell division produces two identical cells through these two major phases

Question: During interphase:

, Page | 2

Ans: Cell grows and DNA is replicated through the following three steps:




1: First growth phase (G1 or first gap)



2: Synthesis phase (S phase)



3:Mitotic Phse (M phase)

Question: First Growth Phase (G1 or first gap)

Ans: -cells increase in size



-reproduce RNA



-"quality assurance" test that the cell will be ready to synthesis DNA




-Length of time is variable, can be from hours to days

Question: Synthesis Phase (S phase)

, Page | 3

Ans: -DNA replicates




-Results in the formation of identical pairs of DNA (chromatids)



-which are attached a t the centromere



-lasts 2-10 hours

Question: Mitotic Phase (M phase)

Ans: -Replicated chromosomes are aligned, separated, and move into 2 new,
identical daughter cells




-takes about 30-60 minutes

Question: Major points of cell regulation are entry and exit from

Ans: -G1 checkpoint



-S Phase




-G2 checkpoint



-M phase

, Page | 4

Question: Restriction Point

Ans: -The transition from the resting phase into an actively dividing phase
(G0-G1) is a point where cellular transformation can occur



-During this time, cells pass through a transition phase known as a restriction
point




-Extracellular growth factors trigger reentry into G1, and GF are required to
send the cells past the restriction point, or the point of no return

Question: G0 Phase (resting phase)

Ans: -After mitosis, cells may enter back into the G1 phase or go into a resting
phase, known as G0




-Most cells in the human body reside in G0

Question: -Exceptions to this are those that are (Resting in G0 phase)

Ans: -Exceptions to this are those that are metabollically active, such as



-granulocytes



-and the epithelium of the GI tract

Question: Cell Cycling Time

Ans: Amount of time from mitosis to mitosis

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