COMLEX Level 1 EXAM ELABORATIONS QUESTIONS AND VERIFIED
COMLEX Level 1
ANSWERS 2025 UPDATE | 100% SOLVED
Study online at https://quizlet.com/_8c2fdw
1. cysteine stone - *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Or-
nithine, Lysine, Arginine
- Does NOT respond to shock wave therapy
2. angiodysplasia most common cause of lower GI bleeding in pt's >60
3. superior mesenteric artery supplies the lower portion of the duodenum, jejunum,
ileum, cecum, ascending colon, and transverse colon
to the splenic flexure
4. pancreatic cancer -usually arises in the *head* of the pancreas
-is associated with *jaundice and pain* due to ob-
struction of the common bile duct
- it is the *4th* most common cause of cancer
-has a very poor prognosis
5. 1. Calcium channel blockers--> Patients with GERD normally have a dysfunction with
specifically smooth muscle antago- LES sphincter tone that allows acid to reflux into
, COMLEX Level 1
Study online at https://quizlet.com/_8c2fdw
nists--> SM dilation the esophagus, thus drugs that affect sphincter tone
2. Alpha adrenergic receptor block- would make GERD worse. What are the name of three
ers --> cause dilation of vessels in- drug categories that do this?
stead of constriction
3. Beta 2 agonists: causes dilation of
smooth muscle vessels
6. celiac disease malabsorption syndrome caused by an immune reac-
tion to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa
and causes steatorrhea, diarrhea, bloating and ab-
dominal pain
-*also associated with other autoimmune disorders
like hashimotos thyroiditis*
7. make NPO, Place on an NG tube and after a patient comes to the ER with sudden onset of
suction obstruction out--> this will pain and abdominal distention W/O peritoneal signs
usually resolve obstruction and after x-ray you diagnose her with a small bowel
obstruction. What do you do next?
8. Low total calcium due to low albu- In a patient with liver cirrhosis what calcium levels
min levels from cirrhosis (95% of would you expect to see?
Ca2+ is bound to albumin) and nor-
mal ionized Ca2+ because PTH reg- Would there be signs of hypocalcemia--> tetany,
ulates free ionized Ca2+ indepen- paresthesias, abdominal cramps?
dently--> that is why there are no
signs go hypocalcemia
9. T5-T11 where would you find a viserosomatic reflex resulting
in placatory changes of the pancreas?
10. Deferoxamine (Desferal)
, COMLEX Level 1
Study online at https://quizlet.com/_8c2fdw
iron chelating agent used in the treatment of iron
intoxication
11. short leg syndrome when a patient presents with a flexible scoliotic curve
it is important to evaluate for...
12. inferior trunk--> encompasses Infarct to what trunk of the Left MCA results in Wer-
broadmann areas 22,39,40 which nicke's aphasia?
are in the temporal region
13. Superior division--> encompasses Infarct to what trunk of the Left MCA results in Broca's
brooks area, frontal eye field, pri- aphasia?
mary motor cortex and primary so-
matosensory cortex
14. Osteosarcoma bone tumor that is present in young adult males that
involves the metaphysis of the long bones
15. Ewing's sarcoma t(11;22) bone tumor that is present in young adult males that
involves the *diaphysis(mid-shaft)* of the long bones.
16. fibrosarcoma malignant fibroblasts within a collagenous matrix
17. chondrosarcoma osseous sarcomas that affect older patients and has
a predilection for flat bones in the *shoulders and
pelvis*
18. tyrosine, due to a defect in pheny- PKU presents as failure to thrive, mental retardation,
lalanine hydroxylase gapped teeth, etc. What is the amino acid that needs
to be supplemented due to a defect in what enzyme?
19. Rib 2 where does the posterior scalene attach to?
20. Paclitaxel
, COMLEX Level 1
Study online at https://quizlet.com/_8c2fdw
used in the treatment of breast and ovarian cancer
MOA: hyper stabilization of polymerized micro-
tubules--> prevents the breakdown of the mitotic
spindle
21. restrictive barrier maximum distance a patient can actually move a joint,
can be pathologic
22. narcissistic personality disorder patterns of grandiosity, need for admiration, lack of
empathy for others
23. A carotid massage causes an in- what does a carotid massage do and how does it affect
crease in stretch of the carotid the AV node?
baroreceptors which causes a re-
flexive PARASYM response which
slows down the conduction velocity
through the AV node this slowing
down Heart Rate--> used in parox-
ysmal supra ventricular tachycardia
24. Chronic myelogenous leukemia a form of leukemia characterized by the accumulation
t(9;22)--> Philly chx of abnormal, mature granulocytes (granulocytes are a
type of white blood cell), mild anemia, thrombocytosis
and basophilia. What is the associated chromosomal
translocation?
25. Burkitt's lymphoma t(8;14) germinal B celll lymphoma that is associated with a
translocation between c-MYC and the Ig heavy chain
on which two chromosomes? It is endemic in the con-
tinent of Africa which produces this
COMLEX Level 1
ANSWERS 2025 UPDATE | 100% SOLVED
Study online at https://quizlet.com/_8c2fdw
1. cysteine stone - *Hexagonal* stones
- *Ground, glass appearance*
- *(+) urinary cyanide nitroprusside test
- Defect in renal transport of COLA: Cysteine, Or-
nithine, Lysine, Arginine
- Does NOT respond to shock wave therapy
2. angiodysplasia most common cause of lower GI bleeding in pt's >60
3. superior mesenteric artery supplies the lower portion of the duodenum, jejunum,
ileum, cecum, ascending colon, and transverse colon
to the splenic flexure
4. pancreatic cancer -usually arises in the *head* of the pancreas
-is associated with *jaundice and pain* due to ob-
struction of the common bile duct
- it is the *4th* most common cause of cancer
-has a very poor prognosis
5. 1. Calcium channel blockers--> Patients with GERD normally have a dysfunction with
specifically smooth muscle antago- LES sphincter tone that allows acid to reflux into
, COMLEX Level 1
Study online at https://quizlet.com/_8c2fdw
nists--> SM dilation the esophagus, thus drugs that affect sphincter tone
2. Alpha adrenergic receptor block- would make GERD worse. What are the name of three
ers --> cause dilation of vessels in- drug categories that do this?
stead of constriction
3. Beta 2 agonists: causes dilation of
smooth muscle vessels
6. celiac disease malabsorption syndrome caused by an immune reac-
tion to gliadian protein in gluten
-Tissue transglutaminase
-results in villous atrophy of small intestine mucosa
and causes steatorrhea, diarrhea, bloating and ab-
dominal pain
-*also associated with other autoimmune disorders
like hashimotos thyroiditis*
7. make NPO, Place on an NG tube and after a patient comes to the ER with sudden onset of
suction obstruction out--> this will pain and abdominal distention W/O peritoneal signs
usually resolve obstruction and after x-ray you diagnose her with a small bowel
obstruction. What do you do next?
8. Low total calcium due to low albu- In a patient with liver cirrhosis what calcium levels
min levels from cirrhosis (95% of would you expect to see?
Ca2+ is bound to albumin) and nor-
mal ionized Ca2+ because PTH reg- Would there be signs of hypocalcemia--> tetany,
ulates free ionized Ca2+ indepen- paresthesias, abdominal cramps?
dently--> that is why there are no
signs go hypocalcemia
9. T5-T11 where would you find a viserosomatic reflex resulting
in placatory changes of the pancreas?
10. Deferoxamine (Desferal)
, COMLEX Level 1
Study online at https://quizlet.com/_8c2fdw
iron chelating agent used in the treatment of iron
intoxication
11. short leg syndrome when a patient presents with a flexible scoliotic curve
it is important to evaluate for...
12. inferior trunk--> encompasses Infarct to what trunk of the Left MCA results in Wer-
broadmann areas 22,39,40 which nicke's aphasia?
are in the temporal region
13. Superior division--> encompasses Infarct to what trunk of the Left MCA results in Broca's
brooks area, frontal eye field, pri- aphasia?
mary motor cortex and primary so-
matosensory cortex
14. Osteosarcoma bone tumor that is present in young adult males that
involves the metaphysis of the long bones
15. Ewing's sarcoma t(11;22) bone tumor that is present in young adult males that
involves the *diaphysis(mid-shaft)* of the long bones.
16. fibrosarcoma malignant fibroblasts within a collagenous matrix
17. chondrosarcoma osseous sarcomas that affect older patients and has
a predilection for flat bones in the *shoulders and
pelvis*
18. tyrosine, due to a defect in pheny- PKU presents as failure to thrive, mental retardation,
lalanine hydroxylase gapped teeth, etc. What is the amino acid that needs
to be supplemented due to a defect in what enzyme?
19. Rib 2 where does the posterior scalene attach to?
20. Paclitaxel
, COMLEX Level 1
Study online at https://quizlet.com/_8c2fdw
used in the treatment of breast and ovarian cancer
MOA: hyper stabilization of polymerized micro-
tubules--> prevents the breakdown of the mitotic
spindle
21. restrictive barrier maximum distance a patient can actually move a joint,
can be pathologic
22. narcissistic personality disorder patterns of grandiosity, need for admiration, lack of
empathy for others
23. A carotid massage causes an in- what does a carotid massage do and how does it affect
crease in stretch of the carotid the AV node?
baroreceptors which causes a re-
flexive PARASYM response which
slows down the conduction velocity
through the AV node this slowing
down Heart Rate--> used in parox-
ysmal supra ventricular tachycardia
24. Chronic myelogenous leukemia a form of leukemia characterized by the accumulation
t(9;22)--> Philly chx of abnormal, mature granulocytes (granulocytes are a
type of white blood cell), mild anemia, thrombocytosis
and basophilia. What is the associated chromosomal
translocation?
25. Burkitt's lymphoma t(8;14) germinal B celll lymphoma that is associated with a
translocation between c-MYC and the Ig heavy chain
on which two chromosomes? It is endemic in the con-
tinent of Africa which produces this
