WGU785
FinalExam
Latest2025
Q&A
,WGU 785 Final Exam Latest 2025 With
Complete Solution
HemophiliaLPedigreeL-
LFatherLhasLhemophilia,LmotherLdoesLnot.LWhatLisLtheLoutcomeLforLtheirLkids?
CorrectLanswer-LHisLdaughtersLwouldLbeLcarriers.LThisLisLx-linkLrecessive.
Autosomal:
Dominant:
CorrectLanswer-
LAutosomal:LmalesLandLfemalesLequallyLaffected.LDominant:Lnon-
carrierLparents
polymeraseLchainLreactionL(PCR)
CorrectLanswer-
LTheLprocessLofLcopyingLDNALinLtheLlab.LUsesLTemplateLDNA,LNucleotidesL(dNTPS),LDN
ALPolymerase,LandLDNALprimers.
3LStepsLofLPCR
CorrectLanswer-L1.LDenaturation:LDNALisLheatedLtoL95CLtoLseparateLit.
2. Annealing:LreactionLisLcooledLtoL50C;LprimersLstickLtoLtheLDNALyouLwantLtoLcopyLandLa
ddLDNALpolymerase.
3. Elongation:LreactionLheatedLtoL70CLandLDNALpolymerase,LaddingLnucleotidesLbuildingL
aLnewLDNALstrand.
BaseLExcisionLRepairL(BER)
CorrectLanswer-
LHowLyouLrepairLaLmutation.LBERLisLusedLtoLrepairLdamageLtoLaLbaseLcausedLbyLharmfulLmol
ecules.LYouLremoveLtheLbaseLthatLisLdamagedLandLreplaceLit.
*BERLremovesLaLsingleLnucleotide*
DNALglycolsylaseL-LseesLdamagedLDNALandLremovesLit.
DNALpolymerase-putsLtheLrightLoneLbackLinLwhileLDNALligaseLsealsLit.
MismatchLrepairL(MMR)LoccursLduring:
CorrectLanswer-
Lreplication.LDNALpolymeraseLproofreadsLbutLsometimesLaLmismatchLpairLgetsLthrough.L
MMRLremovesLaLlargeLsectionLofLtheLnucleotidesLfromLtheLnewLDNALandLDNALpolymeras
eLtriesLagain.L(Ex:LC-TLinsteadLofLC-A)
MismatchLRepairLcorrectsLwhatLkindLofLDNALdamage?
CorrectLanswer-LWhenLaLbaseLisLmismatchedLdueLtoLerrorsLinLreplication.LSuchLasLG-
TLinsteadLofLG-C.LDNALpolymeraseLcomesLbyLandLfixesLit.
WhatLhappensLwhenLDNALpolymeraseLbindsLtoLDNALtoLmakeLRNA?
, CorrectLanswer-
LTRANSCRIPTION!LDNALpolymeraseLtakesLtheLindividualLnucleotidesLandLmatchesLthemL
toLtheLparentalLsequencesLtoLensureLaLcorrectLpair.LItLmustLbindLwithLRNALprimerLtoLwork.
WhatLisLneededLforLDNALreplication?L
CorrectLanswer-LDNALpolymerase
NonsenseLMutation
CorrectLanswer-
LChangeLinL1LnucleotideLproducesLaLSTOPLcodonLStop=LnonsenseLbecauseLitLisLnoLmore.
SilentLMutation
CorrectLanswer-
LChangeLinL1LnucleotideLbutLcodesLforLtheLsameLaminoLacid.LSilent=LtheLchangeLdoesn'tLcha
ngeLtheLnameLofLtheLprotein
MissenseLMutation
CorrectLanswer-
LChangeLinL1LnucleotideLleadsLtoLaLcodeLforLaLdifferentLaminoLacid.LMissenseL=LmistakeLwasL
made.
WhatLhappendsLduringLRNALsplicing?
CorrectLanswer-
LDuringLRNALsplicingLintronsLareLcutLout,LtheLremainingLexonsLareLjoinedLtogether.
5'ATGLAGTLCTCLTCTL3'
FindLtheLDNALtemplateLstrand.
CorrectLanswer-L3'TACLTCALGAGLAGAL5'
TheLDNALtemplateLstrandLisLcomplimentary.LSoLstartLwithLtheLoppositeLnumber,LthenLgoL
L-RLwithLtheLcomplimentaryLletter.
5'ATGLAGTLCTCLTCTL3'
WhatLisLtheLcorresondingLmRNALsequence?LCor
rectLanswer-L5'AUGLAGULCUCLUCUL3'
ThisLsequenceLisLtheLsameLasLtheLcodingLstrandLexceptLTLchangesLtoLULbecauseLitLisLRN
A.LRNALdoesn'tLhaveLT.
HowLwouldLaLmutationLfromLCTCLtoLATCLaffectLtheLproteinLsequence?L(CTC/ATCL-
LcodingLstrand,LAUCL-LmRNALstrand)
CorrectLanswer-
LThisLwillLmakeLaLmissenseLmutationLbecauseLitLchangesLtheLnameLofLtheLprotein.L(lookLat
LtheLchartLprovided.)LmissenseL=Lmistake
DNALreplicationLprocess
CorrectLanswer-LDNAL->TranscriptionL->LRNAL->LTranslationL->LPolypeptide
DescribeLhowLyouLwouldLfindLwhatLionizedLAlanineLlooksLlike.
FinalExam
Latest2025
Q&A
,WGU 785 Final Exam Latest 2025 With
Complete Solution
HemophiliaLPedigreeL-
LFatherLhasLhemophilia,LmotherLdoesLnot.LWhatLisLtheLoutcomeLforLtheirLkids?
CorrectLanswer-LHisLdaughtersLwouldLbeLcarriers.LThisLisLx-linkLrecessive.
Autosomal:
Dominant:
CorrectLanswer-
LAutosomal:LmalesLandLfemalesLequallyLaffected.LDominant:Lnon-
carrierLparents
polymeraseLchainLreactionL(PCR)
CorrectLanswer-
LTheLprocessLofLcopyingLDNALinLtheLlab.LUsesLTemplateLDNA,LNucleotidesL(dNTPS),LDN
ALPolymerase,LandLDNALprimers.
3LStepsLofLPCR
CorrectLanswer-L1.LDenaturation:LDNALisLheatedLtoL95CLtoLseparateLit.
2. Annealing:LreactionLisLcooledLtoL50C;LprimersLstickLtoLtheLDNALyouLwantLtoLcopyLandLa
ddLDNALpolymerase.
3. Elongation:LreactionLheatedLtoL70CLandLDNALpolymerase,LaddingLnucleotidesLbuildingL
aLnewLDNALstrand.
BaseLExcisionLRepairL(BER)
CorrectLanswer-
LHowLyouLrepairLaLmutation.LBERLisLusedLtoLrepairLdamageLtoLaLbaseLcausedLbyLharmfulLmol
ecules.LYouLremoveLtheLbaseLthatLisLdamagedLandLreplaceLit.
*BERLremovesLaLsingleLnucleotide*
DNALglycolsylaseL-LseesLdamagedLDNALandLremovesLit.
DNALpolymerase-putsLtheLrightLoneLbackLinLwhileLDNALligaseLsealsLit.
MismatchLrepairL(MMR)LoccursLduring:
CorrectLanswer-
Lreplication.LDNALpolymeraseLproofreadsLbutLsometimesLaLmismatchLpairLgetsLthrough.L
MMRLremovesLaLlargeLsectionLofLtheLnucleotidesLfromLtheLnewLDNALandLDNALpolymeras
eLtriesLagain.L(Ex:LC-TLinsteadLofLC-A)
MismatchLRepairLcorrectsLwhatLkindLofLDNALdamage?
CorrectLanswer-LWhenLaLbaseLisLmismatchedLdueLtoLerrorsLinLreplication.LSuchLasLG-
TLinsteadLofLG-C.LDNALpolymeraseLcomesLbyLandLfixesLit.
WhatLhappensLwhenLDNALpolymeraseLbindsLtoLDNALtoLmakeLRNA?
, CorrectLanswer-
LTRANSCRIPTION!LDNALpolymeraseLtakesLtheLindividualLnucleotidesLandLmatchesLthemL
toLtheLparentalLsequencesLtoLensureLaLcorrectLpair.LItLmustLbindLwithLRNALprimerLtoLwork.
WhatLisLneededLforLDNALreplication?L
CorrectLanswer-LDNALpolymerase
NonsenseLMutation
CorrectLanswer-
LChangeLinL1LnucleotideLproducesLaLSTOPLcodonLStop=LnonsenseLbecauseLitLisLnoLmore.
SilentLMutation
CorrectLanswer-
LChangeLinL1LnucleotideLbutLcodesLforLtheLsameLaminoLacid.LSilent=LtheLchangeLdoesn'tLcha
ngeLtheLnameLofLtheLprotein
MissenseLMutation
CorrectLanswer-
LChangeLinL1LnucleotideLleadsLtoLaLcodeLforLaLdifferentLaminoLacid.LMissenseL=LmistakeLwasL
made.
WhatLhappendsLduringLRNALsplicing?
CorrectLanswer-
LDuringLRNALsplicingLintronsLareLcutLout,LtheLremainingLexonsLareLjoinedLtogether.
5'ATGLAGTLCTCLTCTL3'
FindLtheLDNALtemplateLstrand.
CorrectLanswer-L3'TACLTCALGAGLAGAL5'
TheLDNALtemplateLstrandLisLcomplimentary.LSoLstartLwithLtheLoppositeLnumber,LthenLgoL
L-RLwithLtheLcomplimentaryLletter.
5'ATGLAGTLCTCLTCTL3'
WhatLisLtheLcorresondingLmRNALsequence?LCor
rectLanswer-L5'AUGLAGULCUCLUCUL3'
ThisLsequenceLisLtheLsameLasLtheLcodingLstrandLexceptLTLchangesLtoLULbecauseLitLisLRN
A.LRNALdoesn'tLhaveLT.
HowLwouldLaLmutationLfromLCTCLtoLATCLaffectLtheLproteinLsequence?L(CTC/ATCL-
LcodingLstrand,LAUCL-LmRNALstrand)
CorrectLanswer-
LThisLwillLmakeLaLmissenseLmutationLbecauseLitLchangesLtheLnameLofLtheLprotein.L(lookLat
LtheLchartLprovided.)LmissenseL=Lmistake
DNALreplicationLprocess
CorrectLanswer-LDNAL->TranscriptionL->LRNAL->LTranslationL->LPolypeptide
DescribeLhowLyouLwouldLfindLwhatLionizedLAlanineLlooksLlike.