CSO Exam: Interactions with Cancer Medications Updated 202/2026 New!!

CSO Exam: Interactions with Cancer Medications
Updated 202/2026 New!!
Bortezomib - Correct Answers (Velcade) Il` Il` Il` Il` Il` Il` Il` Il` Il`




IV or SQ
Il` Il`




-green tea should be avoided while taking this drug, especially in liquid and capsule forms
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




-CYP3A4 inhibitors or inducers may alter drug activity, monitor closely
Il` Il` Il` Il` Il` Il` Il` Il` Il`




Il` Capecitabine - Correct Answers Xeloda Il` Il` Il` Il` Il` Il` Il` Il` Il`




Oral directions: take within 30 mins of a mealw/full glass of water
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




-altered coagulation when taken with Warfarin, monitor closely
Il` Il` Il` Il` Il` Il` Il`




-Vitamin B6 (50-100mg 2-3x/day) may help to prevent/reduce the incidence and severity of
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




foot/hand syndrome
Il` Il`




Il` Cetuximab - Correct Answers Erbitux Il` Il` Il` Il` Il` Il` Il` Il` Il`




IV



-monitor serum mag and calcium levels closely Il` Il` Il` Il` Il` Il`




-at risk populations: elderly, hypomagnesia at baseline, pts who have received prior tx
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




w/oxaliplatin
Il`




Il` Cisplatin - Correct Answers Platinol Il` Il` Il` Il` Il` Il` Il` Il` Il`




IV



-rigorous hydration is necessary to prevent nephrotoxicity
Il` Il` Il` Il` Il` Il`

, -carefully monitor renal function (BUN and Cr) and serum electrolytes (Mg, Ca, Na, K) levels
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




closely
Il`




-at risk populations: elderly, hypomag or those w/impaired renal function at baseline
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




Il` cyclophosphamide - Correct Answers Cytoxan Il` Il` Il` Il` Il` Il` Il` Il` Il`




IV or oral
Il` Il`




Oral: take preferably earlier in the day and w/vigorous hydration throughout the day
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




-advise vigorous oral hydration (3L/day) Il` Il` Il` Il`




-instruct pts to empty bladder every 2-3 hours during waking hours
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




-Mesna is given with high-dose cyclophosphamide to prevent hemorrhagic cystitis
Il` Il` Il` Il` Il` Il` Il` Il` Il`




-increases the effect of anticoagulants, so dose may need to be decreased Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




Il` Dasatinib - Correct Answers Sprycel Il` Il` Il` Il` Il` Il` Il` Il` Il`




Oral: take with or w/o foodIl` Il` Il` Il` Il`




-avoid CYP3A4 inducers which may decrease drug activity (St. John's Wort, phenobarbital)
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




-avoid CYP3A4 inhibitors which may increase drug activity (grapefruit juice, ketoconazole,
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




erythromycin)
Il`




-do not crush or cut drug
Il` Il` Il` Il` Il`




Il` Busulfan - Correct Answers Myleran Il` Il` Il` Il` Il` Il` Il` Il` Il`




-aspirin containing OTC medications should be avoided while taking this drug
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`




Il` Bexarotene - Correct Answers Targretin Il` Il` Il` Il` Il` Il` Il` Il` Il`