FINAL EXAM 2025 QUESTIONS AND
ANSWERS
The kidney consists of specialized vascular and tubular structures (the neprhon) which
collaborate in the production of urine: - ANS The glomerular capillary is surrounded by an
epithelial structure which forms the beginning of the tubule.
A diagnostic renal clearance experiment is conducted and the following steady states
(=equilibrium) measurements are obtained on a 34 y/o male subject, weighing 60kg (assume
that the renal plasma flow (RPF) is the same as the effective renal plasma flow ERPF)):
urine inulin= 200mg/100ml
plasma inulin = 4mg/100ml
urine flow (V)= 2ml/min
urine PAH= 1200mg/100ml
plasma PAH = 6mg/100ml
What is the GFR? - ANS 100ml/min
Any substance which is freely filtered at the glomerulus, is reabsorbed and not secreted, will
have a renal clearance that is - ANS less than the clearance of inulin
b/c a fractional clearance of 1.0 indicates net tubular reabsorption of freely filtered substances
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