WGU D116 Pharmacology Questions
And Answers
A mpatient mpresents mto man memergency mroom mcomplaining mof mpalpitations mand mirregular
mheartbeat. mThe madvanced mpractice mregistered mnurse m(APRN) mplaces mthe mpatient mon ma
mcardiac mmonitor mand mobserves matrial mfibrillation. mThe mAPRN morders mdofetilide.
How mshould mthe mAPRN mrecommend mthis mmedication mbe mtaken? m- mAnswer m- mYES mWith mfood
mor man mempty mstomach
A m70-year-old mmale mcalls ma mclinic mcomplaining mof mchest mpain mthat mstarted mafter mhaving
msexual mactivity. mHe mtook msildenafil m50 mmg mabout meight mhours mago. mHe mhas mnitroglycerin
m0.3 mmg mon mhand.
How mshould mthe madvanced mpractice mregistered mnurse mrespond? m- mAnswer m- mDo mnot mtake
mthe mnitroglycerin mand mcall m911
Taking mthe mmedications mtogether mcan mcause ma mserious mdrop min mblood mpressure mleading mto
mcardiovascular mcollapse.
A mpatient mdiagnosed mwith mbipolar mdisorder mwho mis min ma mmental mhealth mclinic mis mdiscussing
mthe mpossibility mof mbeginning mlithium mwith man madvanced mpractice mregistered mnurse m(APRN).
mThe mpatient mexpresses munderstanding mand mwishes mto mproceed mwith mtreatment. mThe mAPRN
mexplains mto mthe mpatient mthat mthis mmedication mrequires mspecific mlab mmonitoring mand mwants
mto mdraw mbaseline mlabs. mThe mpatient masks mwhy mthe mtest mis mneeded.
Which mexplanation mshould mthe mAPRN mprovide mto mthis mpatient? m- mAnswer m- mA mbaseline
mblood murea mnitrogen m(BUN) mand mcreatinine m(CREA) mlevel mneeds mto mbe mdrawn mto massess
mkidney mfunction mprior mto mtreatment.
This mdrug mcan mcause mdecreased mrenal mfunction, mand ma mbaseline mshould mbe mdrawn mfor
mfuture mcomparison.
An madvanced mpractice mregistered mnurse m(APRN) mis mreviewing mthe mmedications mthat mwill mbe
mcommonly mexperienced mwith ma mnew mnurse mto mdetermine mwhether mthe mdrugs mare msafe mfor
,mthe mpatients. mThe mnew mnurse mis mgiven ma mscenario mwhere ma mpatient mis mbeing mprescribed
msildenafil m25 mmg mpo mprn, ma mprototype mdrug mfor merectile mdysfunction.
Which mpatient mmay mtake mthis mdrug msafely? m- mAnswer m- mYES mA m54-year-male mwith ma
mmedical mhistory mof mhypertension, mmild meczema, mand mprevious mhistory mof ma murolithiasis
mwhere mall mis mwell mcontrolled mand mthere mare mno mcurrent mcomplications
A m30-year-old mpatient mpresents mto ma mprimary mcare mclinic mwith ma mhistory mof manxiety. mThe
madvanced mpractice mregistered mnurse mreviews mthe mmechanism mof maction mby mwhich mmany
mneuropharmacological magents mact mand mdecides mto mprescribe mcitalopram.
What mis mthe mmechanism mof maction mof mthis mmedication? m- mAnswer m- mYES mInfluences
mreceptor mactivity mon mtarget mcells
Correct! mThis mmedication minfluences mthe mactivity min mthe mreceptors, mand mit mtargets mcells.
A mpatient mis madmitted mwith ma mdiagnosis mof mHuntington mdisease. mOn madmission, mthe mpatient
mexhibits muncontrolled mtwitching, mdifficulty mwalking, mtrouble mswallowing, mconfusion, mand
mmemory mloss. mThe madvanced mpractice mregistered mnurse m(APRN) mprescribes mbaclofen.
What mis mthe mmechanism mof maction mof mthis mmedication? m- mAnswer m- mNO mModulates mthe
meffects mof mglutamate mat mNMDA mreceptors
YES mInhibits mneurotransmitter mGABA
NO mHalts mthe mbreakdown mof macetylcholine mby macetylcholinesterase
Alters mthe msynthesis mand mrelease mof mnorepinephrine, mserotonin, mand mdopamine
Incorrect. mCholinesterase minhibitors mprevent mthe mbreakdown mof macetylcholine mby
macetylcholinesterase. mThey mare mused min mpatients mwith mAlzheimer's.
Correct! mHuntington's mdisease minvolves ma mdeficiency mof mthe mneurotransmitters macetylcholine
mand my-aminobutyric macid min mthe mbasal mganglia mand mextrapyramidal msystem.
A m21-year-old mpatient maccompanied mby ma mparent mcomes mto ma mclinic mfor man memergency
mvisit mwith man madvanced mpractice mregistered mnurse m(APRN) mfollowing ma mseizure. mUpon
minterviewing mthe mpatient mand mthe mparent, mthe mAPRN mdetermines mthat mthe mseizure mis
mclassified mby mmarked mimpairment mof mconsciousness mand mis mfollowed mby ma mperiod mof
mcentral mnervous msystem m(CNS) mdepression.
Which mtype mof mseizure mis mthis mpatient mexperiencing? m- mAnswer m- mAtonic
NO mMyoclonic
,YES mTonic-clonic
Absence
Incorrect. mMyoclonic mseizures mconsist mof ma msudden mmuscle mcontraction mthat mlasts mfor mjust
mone msecond.
Correct! mA mtonic-clonic mseizure mis ma mtype mof mseizure mthat mis malso mcalled ma mconvulsion. mThis
mtype mof mseizure mcan minclude mmuscle mstiffness, mloss mof mconsciousness, mand mbody mjerking.
A mpatient mhas mbeen mtaking moral moxycodone mevery msix mhours mfor mback mpain mduring mthe
mpast mthree myears. mThe mpatient msuddenly mdecides mto mstop mtaking mthe mpain mmedication mand
mis mtrying man malternative mtherapy mwithout ma mclinician's mapproval.
Which mrisk mis mof mclinical mconcern? m- mAnswer m- mYES mPhysical mdependence
Correct! mThe mpatient msuddenly mstopping mthe mmedication mwill mcause mphysical msymptoms mthat
mcan mrange mfrom mnausea mto mseizures.
An madvanced mpractice mregistered mnurse mhas mdiagnosed ma m44-year-old mmale mwith mdepression.
mA mplan mis mdeveloped mto mstart mtreatment mwith mmedication. mThe mpatient mhas ma mhistory mof
msexual mdysfunction mand mis mconcerned mabout mtaking mmedication mthat mmay mworsen mthis
mcondition.
Which mantidepressant mhas mthe mbenefit mof menhancing mlibido? m- mAnswer m- mYES mBupropion
Correct! mBupropion mdoes mnot mcause msexual mdysfunction. mThis mwill mhelp mthe mpatient mwith ma
mhistory mof msexual mdysfunction. mThis mwill menhance mthe mpatient's mlibido, mwhich mwill mhelp
mwith mboth mdepression mand msexual mdysfunction.
A mpatient mis mwheezing mand mshort mof mbreath. mThe mnurse massesses ma mheart mrate mof m88
mbeats mper mminute, ma mrespiratory mrate mof m24 mbreaths mper mminute, mand ma mblood mpressure
mof m124/78 mmm mHg. mThe mprescriber morders ma mnonspecific mbeta-agonist mmedication.
Besides mevaluating mthe mpatient mfor ma mreduction min mrespiratory mdistress, mthe mnurse mshould
mmonitor mfor mwhich mside meffect? m- mAnswer m- mYES mTachycardia
Correct! mBeta-agonists mare mused mfor masthma mbecause mof mtheir mbeta2 meffects mon mbronchial
msmooth mmuscle, mcausing mdilation. mBeta1 meffects mcause mtachycardia mand mhypertension. mBeta
mreceptors mdo mnot mexert meffects mon mthe mbladder.
, A mpatient mis mexperiencing mtoxic mside meffects mfrom matropine, mincluding mdelirium mand
mhallucinations. mWhich mmedication mshould mthe mprovider madminister? m- mAnswer m- mYES
mPhysostigmine
Correct! mPhysostigmine mis mthe mdrug mof mchoice mfor mtreating mpoisoning mfrom matropine mand
mother mdrugs mthat mcause mmuscarinic mblockade. mDonepezil mis mused mto mtreat mAlzheimer
mdisease. mEdrophonium mis mused mto mdistinguish mbetween ma mmyasthenic mcrisis mand ma
mcholinesterase minhibitor moverdose. mNeostigmine mdoes mnot mcross mthe mblood-brain mbarrier mand
mwould mnot meffectively mtreat mthis mpatient's mcentral mnervous msystem m(CNS) msymptoms.
A mpatient mbrought mto mthe memergency mdepartment mrequires msutures. mThe mprescriber morders
ma mlocal manesthetic mwith mepinephrine.
The mepinephrine mis mordered mto m___________. m- mAnswer m- mallow ma mreduced mdose mof mthe
manesthetic
Correct! mEpinephrine mprolongs mabsorption mof mthe manesthetic mbecause mit mis man malpha1
magonist. mIt mis mfrequently mcombined mwith ma mlocal manesthetic mfor mthis mpurpose mso mthe
mamount mof manesthetic mrequired mmay mbe mreduced. mLocal manesthetics mdo mnot minduce
mhypertension; mtherefore, mepinephrine mwould mnot mbe mneeded mto mprevent mit. mEpinephrine
mdoes mnot mact mas man mantiemetic mand mwould mnot mreduce manesthetic-induced mnausea.
mEpinephrine mis mnot mused mto mreduce mthe mpain mof man minjection.
A mpatient mhas mbeen mdiagnosed mwith mParkinson mdisease m(PD) mand mbegins mtreatment mwith
mcarbidopa. mAfter mseveral mmonths mof mtherapy, mthe mpatient mreports mno mchange min
msymptoms.
As mthe mprovider, myou mshould mdo mwhich mof mthe mfollowing? m- mAnswer m- mIncrease mthe mdose
mof mcarbidopa
Discuss mthe m"on-off" mphenomenon
Reevaluate mthe mdiagnosis
NO mAdd ma mdopamine magonist
Incorrect. mAdding ma mdopamine magonist mis mnot mindicated.
A mpatient mwho mis mtaking moral mcontraceptives mbegins mtaking mvalproic macid mfor mseizures. mAfter
ma mweek mof mtherapy mwith mvalproic macid, mthe mpatient mtells mthe mnurse mthat mshe mis
mexperiencing mnausea.
And Answers
A mpatient mpresents mto man memergency mroom mcomplaining mof mpalpitations mand mirregular
mheartbeat. mThe madvanced mpractice mregistered mnurse m(APRN) mplaces mthe mpatient mon ma
mcardiac mmonitor mand mobserves matrial mfibrillation. mThe mAPRN morders mdofetilide.
How mshould mthe mAPRN mrecommend mthis mmedication mbe mtaken? m- mAnswer m- mYES mWith mfood
mor man mempty mstomach
A m70-year-old mmale mcalls ma mclinic mcomplaining mof mchest mpain mthat mstarted mafter mhaving
msexual mactivity. mHe mtook msildenafil m50 mmg mabout meight mhours mago. mHe mhas mnitroglycerin
m0.3 mmg mon mhand.
How mshould mthe madvanced mpractice mregistered mnurse mrespond? m- mAnswer m- mDo mnot mtake
mthe mnitroglycerin mand mcall m911
Taking mthe mmedications mtogether mcan mcause ma mserious mdrop min mblood mpressure mleading mto
mcardiovascular mcollapse.
A mpatient mdiagnosed mwith mbipolar mdisorder mwho mis min ma mmental mhealth mclinic mis mdiscussing
mthe mpossibility mof mbeginning mlithium mwith man madvanced mpractice mregistered mnurse m(APRN).
mThe mpatient mexpresses munderstanding mand mwishes mto mproceed mwith mtreatment. mThe mAPRN
mexplains mto mthe mpatient mthat mthis mmedication mrequires mspecific mlab mmonitoring mand mwants
mto mdraw mbaseline mlabs. mThe mpatient masks mwhy mthe mtest mis mneeded.
Which mexplanation mshould mthe mAPRN mprovide mto mthis mpatient? m- mAnswer m- mA mbaseline
mblood murea mnitrogen m(BUN) mand mcreatinine m(CREA) mlevel mneeds mto mbe mdrawn mto massess
mkidney mfunction mprior mto mtreatment.
This mdrug mcan mcause mdecreased mrenal mfunction, mand ma mbaseline mshould mbe mdrawn mfor
mfuture mcomparison.
An madvanced mpractice mregistered mnurse m(APRN) mis mreviewing mthe mmedications mthat mwill mbe
mcommonly mexperienced mwith ma mnew mnurse mto mdetermine mwhether mthe mdrugs mare msafe mfor
,mthe mpatients. mThe mnew mnurse mis mgiven ma mscenario mwhere ma mpatient mis mbeing mprescribed
msildenafil m25 mmg mpo mprn, ma mprototype mdrug mfor merectile mdysfunction.
Which mpatient mmay mtake mthis mdrug msafely? m- mAnswer m- mYES mA m54-year-male mwith ma
mmedical mhistory mof mhypertension, mmild meczema, mand mprevious mhistory mof ma murolithiasis
mwhere mall mis mwell mcontrolled mand mthere mare mno mcurrent mcomplications
A m30-year-old mpatient mpresents mto ma mprimary mcare mclinic mwith ma mhistory mof manxiety. mThe
madvanced mpractice mregistered mnurse mreviews mthe mmechanism mof maction mby mwhich mmany
mneuropharmacological magents mact mand mdecides mto mprescribe mcitalopram.
What mis mthe mmechanism mof maction mof mthis mmedication? m- mAnswer m- mYES mInfluences
mreceptor mactivity mon mtarget mcells
Correct! mThis mmedication minfluences mthe mactivity min mthe mreceptors, mand mit mtargets mcells.
A mpatient mis madmitted mwith ma mdiagnosis mof mHuntington mdisease. mOn madmission, mthe mpatient
mexhibits muncontrolled mtwitching, mdifficulty mwalking, mtrouble mswallowing, mconfusion, mand
mmemory mloss. mThe madvanced mpractice mregistered mnurse m(APRN) mprescribes mbaclofen.
What mis mthe mmechanism mof maction mof mthis mmedication? m- mAnswer m- mNO mModulates mthe
meffects mof mglutamate mat mNMDA mreceptors
YES mInhibits mneurotransmitter mGABA
NO mHalts mthe mbreakdown mof macetylcholine mby macetylcholinesterase
Alters mthe msynthesis mand mrelease mof mnorepinephrine, mserotonin, mand mdopamine
Incorrect. mCholinesterase minhibitors mprevent mthe mbreakdown mof macetylcholine mby
macetylcholinesterase. mThey mare mused min mpatients mwith mAlzheimer's.
Correct! mHuntington's mdisease minvolves ma mdeficiency mof mthe mneurotransmitters macetylcholine
mand my-aminobutyric macid min mthe mbasal mganglia mand mextrapyramidal msystem.
A m21-year-old mpatient maccompanied mby ma mparent mcomes mto ma mclinic mfor man memergency
mvisit mwith man madvanced mpractice mregistered mnurse m(APRN) mfollowing ma mseizure. mUpon
minterviewing mthe mpatient mand mthe mparent, mthe mAPRN mdetermines mthat mthe mseizure mis
mclassified mby mmarked mimpairment mof mconsciousness mand mis mfollowed mby ma mperiod mof
mcentral mnervous msystem m(CNS) mdepression.
Which mtype mof mseizure mis mthis mpatient mexperiencing? m- mAnswer m- mAtonic
NO mMyoclonic
,YES mTonic-clonic
Absence
Incorrect. mMyoclonic mseizures mconsist mof ma msudden mmuscle mcontraction mthat mlasts mfor mjust
mone msecond.
Correct! mA mtonic-clonic mseizure mis ma mtype mof mseizure mthat mis malso mcalled ma mconvulsion. mThis
mtype mof mseizure mcan minclude mmuscle mstiffness, mloss mof mconsciousness, mand mbody mjerking.
A mpatient mhas mbeen mtaking moral moxycodone mevery msix mhours mfor mback mpain mduring mthe
mpast mthree myears. mThe mpatient msuddenly mdecides mto mstop mtaking mthe mpain mmedication mand
mis mtrying man malternative mtherapy mwithout ma mclinician's mapproval.
Which mrisk mis mof mclinical mconcern? m- mAnswer m- mYES mPhysical mdependence
Correct! mThe mpatient msuddenly mstopping mthe mmedication mwill mcause mphysical msymptoms mthat
mcan mrange mfrom mnausea mto mseizures.
An madvanced mpractice mregistered mnurse mhas mdiagnosed ma m44-year-old mmale mwith mdepression.
mA mplan mis mdeveloped mto mstart mtreatment mwith mmedication. mThe mpatient mhas ma mhistory mof
msexual mdysfunction mand mis mconcerned mabout mtaking mmedication mthat mmay mworsen mthis
mcondition.
Which mantidepressant mhas mthe mbenefit mof menhancing mlibido? m- mAnswer m- mYES mBupropion
Correct! mBupropion mdoes mnot mcause msexual mdysfunction. mThis mwill mhelp mthe mpatient mwith ma
mhistory mof msexual mdysfunction. mThis mwill menhance mthe mpatient's mlibido, mwhich mwill mhelp
mwith mboth mdepression mand msexual mdysfunction.
A mpatient mis mwheezing mand mshort mof mbreath. mThe mnurse massesses ma mheart mrate mof m88
mbeats mper mminute, ma mrespiratory mrate mof m24 mbreaths mper mminute, mand ma mblood mpressure
mof m124/78 mmm mHg. mThe mprescriber morders ma mnonspecific mbeta-agonist mmedication.
Besides mevaluating mthe mpatient mfor ma mreduction min mrespiratory mdistress, mthe mnurse mshould
mmonitor mfor mwhich mside meffect? m- mAnswer m- mYES mTachycardia
Correct! mBeta-agonists mare mused mfor masthma mbecause mof mtheir mbeta2 meffects mon mbronchial
msmooth mmuscle, mcausing mdilation. mBeta1 meffects mcause mtachycardia mand mhypertension. mBeta
mreceptors mdo mnot mexert meffects mon mthe mbladder.
, A mpatient mis mexperiencing mtoxic mside meffects mfrom matropine, mincluding mdelirium mand
mhallucinations. mWhich mmedication mshould mthe mprovider madminister? m- mAnswer m- mYES
mPhysostigmine
Correct! mPhysostigmine mis mthe mdrug mof mchoice mfor mtreating mpoisoning mfrom matropine mand
mother mdrugs mthat mcause mmuscarinic mblockade. mDonepezil mis mused mto mtreat mAlzheimer
mdisease. mEdrophonium mis mused mto mdistinguish mbetween ma mmyasthenic mcrisis mand ma
mcholinesterase minhibitor moverdose. mNeostigmine mdoes mnot mcross mthe mblood-brain mbarrier mand
mwould mnot meffectively mtreat mthis mpatient's mcentral mnervous msystem m(CNS) msymptoms.
A mpatient mbrought mto mthe memergency mdepartment mrequires msutures. mThe mprescriber morders
ma mlocal manesthetic mwith mepinephrine.
The mepinephrine mis mordered mto m___________. m- mAnswer m- mallow ma mreduced mdose mof mthe
manesthetic
Correct! mEpinephrine mprolongs mabsorption mof mthe manesthetic mbecause mit mis man malpha1
magonist. mIt mis mfrequently mcombined mwith ma mlocal manesthetic mfor mthis mpurpose mso mthe
mamount mof manesthetic mrequired mmay mbe mreduced. mLocal manesthetics mdo mnot minduce
mhypertension; mtherefore, mepinephrine mwould mnot mbe mneeded mto mprevent mit. mEpinephrine
mdoes mnot mact mas man mantiemetic mand mwould mnot mreduce manesthetic-induced mnausea.
mEpinephrine mis mnot mused mto mreduce mthe mpain mof man minjection.
A mpatient mhas mbeen mdiagnosed mwith mParkinson mdisease m(PD) mand mbegins mtreatment mwith
mcarbidopa. mAfter mseveral mmonths mof mtherapy, mthe mpatient mreports mno mchange min
msymptoms.
As mthe mprovider, myou mshould mdo mwhich mof mthe mfollowing? m- mAnswer m- mIncrease mthe mdose
mof mcarbidopa
Discuss mthe m"on-off" mphenomenon
Reevaluate mthe mdiagnosis
NO mAdd ma mdopamine magonist
Incorrect. mAdding ma mdopamine magonist mis mnot mindicated.
A mpatient mwho mis mtaking moral mcontraceptives mbegins mtaking mvalproic macid mfor mseizures. mAfter
ma mweek mof mtherapy mwith mvalproic macid, mthe mpatient mtells mthe mnurse mthat mshe mis
mexperiencing mnausea.
