NUR 354 Neuro-Pharmacology Drug Class Table
For Exam Study Guide With Latest Version 2025
Updates
, lOMoAR cPSD| 56927468
Drug Class Drug Onset/Peak/ MOA/Drug Effects Used For SE/
Duration Contraindications
Cholinergic Agonists or
parasympathetic metic
Muscarinic Bethanechol Onset-30-90min Acts on PNS. Nonobstructive *Monitor BP and RR prior
Cholinergic Receptor (Urecholine) PO Stimulates smooth Urinary and for 1hr post
Drug Peak- 60min PO muscle contraction retention subcutaneous admin. Use
Duration-6hr with caution in obstructive,
ulcerative, or inflammatory
PO
conditions such as COPD,
IBS. SE: increased salivation,
sweating, abdominal
cramping, hypotension that
can lead to fainting
Tx of OD- Atropine
, lOMoAR cPSD| 56927468
Anticholinesterase Physostigmine Onset- <5min Inhibits destruction of Anticholinergic **admin slow over 5min to
inhibitor ne IV/IM acetylcholine by ic toxicity prevent seizures.
Peak-20-40min acetylcholinesterase SE: Bradycardia, asystole,
IM/IV se nervousness, seizures,
urinary frequency, muscle
Duration- 1-
Reverses life twitching and respiratory
2hrs IM/IV paralysis *Use in caution
threatening delirium
with pts that have asthma,
epilepsy, CVD,
Diabetes or in patients on
TCA’s
**Toxic effects with-
Ginkgo biloba
Cholinergic
Blocking Drugs
“Anticholinergics”
,
parasympatholytic,
muscarinic blockers and
antagonists
For Exam Study Guide With Latest Version 2025
Updates
, lOMoAR cPSD| 56927468
Drug Class Drug Onset/Peak/ MOA/Drug Effects Used For SE/
Duration Contraindications
Cholinergic Agonists or
parasympathetic metic
Muscarinic Bethanechol Onset-30-90min Acts on PNS. Nonobstructive *Monitor BP and RR prior
Cholinergic Receptor (Urecholine) PO Stimulates smooth Urinary and for 1hr post
Drug Peak- 60min PO muscle contraction retention subcutaneous admin. Use
Duration-6hr with caution in obstructive,
ulcerative, or inflammatory
PO
conditions such as COPD,
IBS. SE: increased salivation,
sweating, abdominal
cramping, hypotension that
can lead to fainting
Tx of OD- Atropine
, lOMoAR cPSD| 56927468
Anticholinesterase Physostigmine Onset- <5min Inhibits destruction of Anticholinergic **admin slow over 5min to
inhibitor ne IV/IM acetylcholine by ic toxicity prevent seizures.
Peak-20-40min acetylcholinesterase SE: Bradycardia, asystole,
IM/IV se nervousness, seizures,
urinary frequency, muscle
Duration- 1-
Reverses life twitching and respiratory
2hrs IM/IV paralysis *Use in caution
threatening delirium
with pts that have asthma,
epilepsy, CVD,
Diabetes or in patients on
TCA’s
**Toxic effects with-
Ginkgo biloba
Cholinergic
Blocking Drugs
“Anticholinergics”
,
parasympatholytic,
muscarinic blockers and
antagonists
