WGU D398 Intro To Pharmacology -
Antineoplastic Drugs: Questions With In-Depth
Solutions
Side effects of cancer drugs Correct Answer - GI distress, bone
marrow suppression, fatigue, paleness, dizziness, shortness of
breath, alopecia, peripheral neuropathy
What do antimetabolites do? Correct Answer - Kill ALL cells.
They mimic the molecules (starve them) that cells use to grow and
make them unable to divide.
Methotrexate drug class Correct Answer - antimetabolite
Fluorouracil drug class Correct Answer - antimetabolite
Side effects of antimetabolites (methotrexate, fluorouracil)
Correct Answer - stomach issues such as ulcers
What do alkylating agents treat? Correct Answer - several
cancers and prevents cell growth
Name two alkylating agent drugs Correct Answer - cisplatin,
cyclophosphamide
Concerns of alkylating agents Correct Answer - long-term
damage to bone marrow, nervous system damage, ulcers,
pulmonary fibrosis
What do mitotic inhibitors do? Correct Answer - stops mitosis
What are some concerns with mitotic inhibitors? Correct Answer
- peripheral nerve damage, myelosuppression
, What are the side effects of mitotic inhibitors? Correct Answer -
stomach issues, ulcers, increased reaction to sunlight, extravasation
What do antitumor antibiotics do? Correct Answer -
specifically target and kill cancer cells, done by interactions with
genetic material inside cancer cell
Which drug class specifically targets and kills cancer cells? Correct
Answer - antitumor antibiotics
What drug class stops the process of mitosis? Correct Answer -
mitotic inhibitors
What drug class prevents cell growth? Correct Answer -
alkylating agents
What drug class kills all dividing cancer cells? Correct Answer -
antimetabolites
Which medication has a once-in-a-lifetime max dose and why?
Correct Answer - doxorubicin
due to heart damage (cardiotoxicity)
What does doxorubicin treat? Correct Answer - variety of
cancers such as lung, breast, gastric, and ovarian
Doxorubicin drug class Correct Answer - antitumor antibiotics
What are corticosteroids? Correct Answer - Synthetic versions
of hormones used to prevent allergic reactions to treatments.
Reduces pain and swelling and the body's immune response.
Antineoplastic Drugs: Questions With In-Depth
Solutions
Side effects of cancer drugs Correct Answer - GI distress, bone
marrow suppression, fatigue, paleness, dizziness, shortness of
breath, alopecia, peripheral neuropathy
What do antimetabolites do? Correct Answer - Kill ALL cells.
They mimic the molecules (starve them) that cells use to grow and
make them unable to divide.
Methotrexate drug class Correct Answer - antimetabolite
Fluorouracil drug class Correct Answer - antimetabolite
Side effects of antimetabolites (methotrexate, fluorouracil)
Correct Answer - stomach issues such as ulcers
What do alkylating agents treat? Correct Answer - several
cancers and prevents cell growth
Name two alkylating agent drugs Correct Answer - cisplatin,
cyclophosphamide
Concerns of alkylating agents Correct Answer - long-term
damage to bone marrow, nervous system damage, ulcers,
pulmonary fibrosis
What do mitotic inhibitors do? Correct Answer - stops mitosis
What are some concerns with mitotic inhibitors? Correct Answer
- peripheral nerve damage, myelosuppression
, What are the side effects of mitotic inhibitors? Correct Answer -
stomach issues, ulcers, increased reaction to sunlight, extravasation
What do antitumor antibiotics do? Correct Answer -
specifically target and kill cancer cells, done by interactions with
genetic material inside cancer cell
Which drug class specifically targets and kills cancer cells? Correct
Answer - antitumor antibiotics
What drug class stops the process of mitosis? Correct Answer -
mitotic inhibitors
What drug class prevents cell growth? Correct Answer -
alkylating agents
What drug class kills all dividing cancer cells? Correct Answer -
antimetabolites
Which medication has a once-in-a-lifetime max dose and why?
Correct Answer - doxorubicin
due to heart damage (cardiotoxicity)
What does doxorubicin treat? Correct Answer - variety of
cancers such as lung, breast, gastric, and ovarian
Doxorubicin drug class Correct Answer - antitumor antibiotics
What are corticosteroids? Correct Answer - Synthetic versions
of hormones used to prevent allergic reactions to treatments.
Reduces pain and swelling and the body's immune response.
