BIOL 600 KU EXAM 3 QUESTIONS AND
VERIFIED ANSWERS
Which enzymes catalyze the synthesis of phosphoenolpyruvate from pyruvate
and a phosphate group during gluconeogenesis? - ANSWER pyruvate
carboxylase and phosphoenol pyruvate carboxykinase
What mitochondrial transport protein is utilized during the synthesis of
phosphoenolpyruvate from pyruvate and a phosphate group during
gluconeogenesis? - ANSWER malate transporter
Prior to entry of gluconeogenesis, ________ is converted into pyruvate, and
some _________ are converted to oxaloacetate - ANSWER lactate and amino
acids
What are the three inhibitors of phophofructosekinase? - ANSWER ATP
Citrate and H+
In gluconeogenesis, name the two inhibitors of fructose 1,6 bisphosphate -
ANSWER AMP and fructose 2,6 bisphosphate
In gluconeogenesis, pyruvate carboxylase is inhibited by _______ and
stimulated by _________ - ANSWER ADP and acetyl coA
Complete this sentence that describes the Cori Cycle: ______ from ______ is
transported in ________ to the ______ where it is converted to glucose -
ANSWER lactate muscle blood liver
Pyvurate carboxylase requires the vitamin cofactor ____, which serves as a
carrier of activated CO2 - ANSWER biotin
What peptide hormone is released when blood glucose concentration is low? -
ANSWER glucagon
, This stimulates the increase of ______ which stimulates ______ and inhibits
________ - ANSWER
Where is glucose-6-phosphatase found? what does it supply? - ANSWER ER
Glucose
What is pyruvate carboxylase activated by? - ANSWER Acetyl CoA
What is pyruvate carboxylase inhibited by? - ANSWER ADP
What is the substrate for glycogen synthesis? - ANSWER UDP-glucose
What is the role of glycogenin? - ANSWER It makes the primer for glycogen
synthesis
What is the enzyme that removes glucose units from the non-reducing ends of
the glycogen molecule called? - ANSWER glycogen phosphorylase
Glycogen phosphorylase is activated by what protein modification - ANSWER
phosphorylation
What two hormones maintain blood glucose levels within a normal range? -
ANSWER insulin and glucagon
How does protein phosphate 1 regulate glycogen phosphorylate? - ANSWER
by removing the phosphate group from glycogen synthase, which activates
glycogen synthase
How is the role of AMP in allosteric control of glycogen metabolism? -
ANSWER AMP stimulates glycogen phosphorylase and inhibits glycogen
synthase
What is the role of glucose 6-phosphate in allosteric control of glycogen
metabolism? - ANSWER Glucose 6-phosphate stimulates glycogen synthase
and inhibits glycogen phosphorylase.
VERIFIED ANSWERS
Which enzymes catalyze the synthesis of phosphoenolpyruvate from pyruvate
and a phosphate group during gluconeogenesis? - ANSWER pyruvate
carboxylase and phosphoenol pyruvate carboxykinase
What mitochondrial transport protein is utilized during the synthesis of
phosphoenolpyruvate from pyruvate and a phosphate group during
gluconeogenesis? - ANSWER malate transporter
Prior to entry of gluconeogenesis, ________ is converted into pyruvate, and
some _________ are converted to oxaloacetate - ANSWER lactate and amino
acids
What are the three inhibitors of phophofructosekinase? - ANSWER ATP
Citrate and H+
In gluconeogenesis, name the two inhibitors of fructose 1,6 bisphosphate -
ANSWER AMP and fructose 2,6 bisphosphate
In gluconeogenesis, pyruvate carboxylase is inhibited by _______ and
stimulated by _________ - ANSWER ADP and acetyl coA
Complete this sentence that describes the Cori Cycle: ______ from ______ is
transported in ________ to the ______ where it is converted to glucose -
ANSWER lactate muscle blood liver
Pyvurate carboxylase requires the vitamin cofactor ____, which serves as a
carrier of activated CO2 - ANSWER biotin
What peptide hormone is released when blood glucose concentration is low? -
ANSWER glucagon
, This stimulates the increase of ______ which stimulates ______ and inhibits
________ - ANSWER
Where is glucose-6-phosphatase found? what does it supply? - ANSWER ER
Glucose
What is pyruvate carboxylase activated by? - ANSWER Acetyl CoA
What is pyruvate carboxylase inhibited by? - ANSWER ADP
What is the substrate for glycogen synthesis? - ANSWER UDP-glucose
What is the role of glycogenin? - ANSWER It makes the primer for glycogen
synthesis
What is the enzyme that removes glucose units from the non-reducing ends of
the glycogen molecule called? - ANSWER glycogen phosphorylase
Glycogen phosphorylase is activated by what protein modification - ANSWER
phosphorylation
What two hormones maintain blood glucose levels within a normal range? -
ANSWER insulin and glucagon
How does protein phosphate 1 regulate glycogen phosphorylate? - ANSWER
by removing the phosphate group from glycogen synthase, which activates
glycogen synthase
How is the role of AMP in allosteric control of glycogen metabolism? -
ANSWER AMP stimulates glycogen phosphorylase and inhibits glycogen
synthase
What is the role of glucose 6-phosphate in allosteric control of glycogen
metabolism? - ANSWER Glucose 6-phosphate stimulates glycogen synthase
and inhibits glycogen phosphorylase.
