IBSS 1540 Exam 1 – Questions With
Comprehensive Solutions
What is the effect of cortisol on ACTH secretion from the pituitary?
What is the effect? Correct Answer - it inhibits it via a negative
feedback loop. This allows cortisol to be maintained in the body
within a specific range
What is true of cortisol levels in Addison disease? Correct Answer
- cortisol levels are low
What is the effect of low plasma ACTH on the adrenal gland?
Correct Answer - it causes both a decrease in cortisol synthesis
as well as atrophy of the endocrine otgan
What are the permissive effects of cortisol as they relate to the
cardiovascular system? Correct Answer - it is required for
catecholamines to increase the contractility of muscle cells and is
required to control capillary permeability
What main hormone is cortisol permissive to? Correct Answer -
epinephrine
What is the effect of cortisol on the skeletal muscle? Correct
Answer - it stimulates proteolysis
What is the effect of cortisol on fatty acids in the liver? Correct
Answer - it causes them to be converted to ketones
What is the effect of cortisol on the pancreas? Correct Answer -
it stimulates secretion of glucagon
, What is the effect of cortisol on glucose levels? how? Correct
Answer - it raises glucose levels by antagonizing he activity of
insulin and preventing import of glucose into storage forms int eh
skeletal muscle, liver, and adipose tissue
What is the effect of cortisol on carb metabolism in the liver?
Correct Answer - it stimulates gluconeogensis, converting amino
acids from denatured proteins into glucose
What is the effect of cortisol on the adrenal medulla? Correct
Answer - it increases the synthesis and secretion of epinephrine
What is the effect of cortisol on carbohydrate metabolism in
glucose-independent tissues? Correct Answer - it prevents the
expression of glut 4 and impairs the uptake of glucose into these
tisssues
What is the effect of cortisol on protein metabolism in skeletal
muscle? Correct Answer - it stimulates protein breakdown and
sends amino acids to the liver to undergo gluconeogenesis
What is the effect of cortisol protein metabolism in body tissues?
Correct Answer - it antagonizes the activity of insulin and
expression of amino acid transporters in tissues, preventing amino
acids from being taken up
What is the effect of cortisol on protein metabolism in the skin and
connective tissue? Correct Answer - it triggers the breakdown
of proteins into amino acids, causing the skin to be thin
What is the effect of cortisol on lipid metabolism in the adrenal
medulla? Correct Answer - it increases epinephrine synthesis,
which then trigger lipolysis and increases fatty acids
Comprehensive Solutions
What is the effect of cortisol on ACTH secretion from the pituitary?
What is the effect? Correct Answer - it inhibits it via a negative
feedback loop. This allows cortisol to be maintained in the body
within a specific range
What is true of cortisol levels in Addison disease? Correct Answer
- cortisol levels are low
What is the effect of low plasma ACTH on the adrenal gland?
Correct Answer - it causes both a decrease in cortisol synthesis
as well as atrophy of the endocrine otgan
What are the permissive effects of cortisol as they relate to the
cardiovascular system? Correct Answer - it is required for
catecholamines to increase the contractility of muscle cells and is
required to control capillary permeability
What main hormone is cortisol permissive to? Correct Answer -
epinephrine
What is the effect of cortisol on the skeletal muscle? Correct
Answer - it stimulates proteolysis
What is the effect of cortisol on fatty acids in the liver? Correct
Answer - it causes them to be converted to ketones
What is the effect of cortisol on the pancreas? Correct Answer -
it stimulates secretion of glucagon
, What is the effect of cortisol on glucose levels? how? Correct
Answer - it raises glucose levels by antagonizing he activity of
insulin and preventing import of glucose into storage forms int eh
skeletal muscle, liver, and adipose tissue
What is the effect of cortisol on carb metabolism in the liver?
Correct Answer - it stimulates gluconeogensis, converting amino
acids from denatured proteins into glucose
What is the effect of cortisol on the adrenal medulla? Correct
Answer - it increases the synthesis and secretion of epinephrine
What is the effect of cortisol on carbohydrate metabolism in
glucose-independent tissues? Correct Answer - it prevents the
expression of glut 4 and impairs the uptake of glucose into these
tisssues
What is the effect of cortisol on protein metabolism in skeletal
muscle? Correct Answer - it stimulates protein breakdown and
sends amino acids to the liver to undergo gluconeogenesis
What is the effect of cortisol protein metabolism in body tissues?
Correct Answer - it antagonizes the activity of insulin and
expression of amino acid transporters in tissues, preventing amino
acids from being taken up
What is the effect of cortisol on protein metabolism in the skin and
connective tissue? Correct Answer - it triggers the breakdown
of proteins into amino acids, causing the skin to be thin
What is the effect of cortisol on lipid metabolism in the adrenal
medulla? Correct Answer - it increases epinephrine synthesis,
which then trigger lipolysis and increases fatty acids
