NSG 6005 Week 2 & 3 Study Guide Graded A+ 2025

NSG 6005 Week 2 & 3 Study Guide Graded A+ 2025 Chapters 15- Introduction to CNS Medications and Anorexiants 1) Know the major activating and inhibiting neurotransmitters for the CNS Activating: ACh, Dopamine, NE, Epinephrine, Serotonin, Histamine Inhibit: GABA, Glycine 2) Know the major neurotransmitters for the gut ACh, Serotonin, Dopamine 3) Know the major neurotransmitters for the sympathetic and parasympathetic nervous systems Sympathetic: NE (primary) Para: ACh ACh 4) Know the major neurotransmitter that mediates skeletal muscle activity ACh 5) Know the mechanism of action and side effects of stimulant anorexiants Stimulates release NE and/or Dopa from storage sites in nerve terminals in lateral hypothalamic feeding center which causes decreased appetite (stimulate of satiety center) r/t amphetamines (increase in NE and dopa stress hormones: increased HR, RR, decreaed GI motility, and constipation. Side Effects: CNS overstimulation, agitation, confusion, insomnia, dizzy, htn, HA, palpitations, arrhythmias, dry mouth, dilated, pupils, dysuria, constipation, n/v/d, impotence. 6) Know the major drug interactions and contraindications for anorexiant use Contra: pt on serontologic agents (increased risk Se. Synd.) Pt on MAOI (HTN crisis & lithium toxicity) ETOH (CNS depressant) Phenothiazines (psychosis) Insulin/Sulfonylureas (altered requirements: increased glucose uptake which causes decreased BG) Adrenergic blockers (antagonized with co-admin) Phentermine conta with: cardiac & HTN (causes increased HR, BP, palp, and arrhythmias) Orlistat decreased Levothyroxine, increases Warfarin Off-label use with SSRI: Prozac and Phenertime