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carbonic anhydrase inhibitors
- med ending
- site of action
- MOA
- indication
- ADRs
- contraindications - correct answer✔✔-lamide
site of action: PCT
moa: Inhibits enzyme responsible for dehydration of H2CO3 (removes bicarb via
excretion)
Increases urine pH
Reduces aqueous humor production
indication: Glaucoma
Urinary alkalosis
Metabolic acidosis
ADRs: Renal stones, potassium wasting, drowsiness, hypersensitivity
contraindications: Hepatic cirrhosis
Loop Diuretics
- med ending
- site of action
- MOA
- indication
- ADRs
- DI
- contraindications - correct answer✔✔meds: furosemide, bumetanide, torsemide,
ethacrynic acid
site: Loop of Henle
moa: Inhibits Na+/K+/2Cl- transporter
indications: Edema, hypercalcemia, hyperkalemia, anion overdose
ADRs: Hypomagnesemia, hypokalemia, hyperuricemia, ototoxicity
DI: NSAIDs
contraindications: Sulfonamide allergy
Hepatic cirrhosis, renal failure, HF
Thiazide Diuretics
- med ending
- site of action
- MOA
- indication