CURRENT TOPICS 2025 MLS MODULE 1 VERIFIED TO
PASS
Have a qualified laboratory director, Participate, and be successful in, proficiency testing or external
quality assurance, Be performing patient testing Correct answer-To be eligible for CAP
Accreditation the lab must:
o Have a qualified laboratory director
o Participate, and be successful in, proficiency testing or external quality assurance
o Be performing patient testing
Key documents required for CAP Accreditation include Correct answer-o Quality Management Plan
o Chemical Hygiene Plan
o Document Control Process
o Competency Assessment Program
o Test Method Validation Documentation
o Laboratory Director Oversight Documentation
o Laboratory Information System (LIS)—if applicable
TJC, CAP, COLA, A2LA Correct answer-The four remaining agencies are more broad in scope
Laboratory Science Correct answer-Definition: The medical discipline by which clinical lab science
and technology are applied to the care of patients.
Boils Correct answer-Oldest known test was done on urine ( before 400 BC) Physicians poured
patient urine on the ground to see if it attracted insects If insects attracted , patient diagnosed with?
Hippocrates Correct answer-Who developed one of the earliest diagnostic protocols (300 BC)
Included tasting patient's urine, listening to lungs, observing outward appearances?
Rufus of Ephesus Correct answer-First description of hematuria was by? (around 50 BC)
Isaac Judaeus Correct answer-Middle Ages-guidelines for the use of urine as diagnostic tool
developed by? (AD 900 )
First book detailing urine color, density, quality, and sediment written around this time.
Hans and Zacharias Janssen Correct answer-Invention of the microscope by? In late 16th century
Anthanasius Kircher Correct answer-(1602 - 1680) early microscopist that studied causes of
diseases
Antonie van Leeuwenhoek Correct answer-(1632-1723) first to observe bacteria and protozoa
"Father of Microbiology"
Robert Hooke Correct answer-(1635 - 1703) used microscope to document the existence of cells in
vegetables
Marcello Malpighi Correct answer-(1628-1694) "founder of histology," studied embryology of
chicks
, Richard Lower Correct answer-Seventeenth century (1631 - 1691) experiments with blood
transfusions began in England by
William Hewson Correct answer-"Father of Hematology"
Discovered coagulable lymph now known as fibrinogen
Later discovered that fibrinogen is a plasma protein which is converted to fibrin in coagulation
J.W. Trichy Correct answer-Observed Urine sediment in febrile patients
Mathew Dobson Correct answer-Proved the sweetness of Urine in diabetes is caused by sugar
Francis Home Correct answer-Developed yeast test for sugar in urine of diabetic patients
Louis Pasteur Correct answer-1861 -Introduced concept of aerobic and anaerobic bacteria
1867 -Pasteurization ( sterilization by partial heat ) 1881 -Produced vaccine against anthrax
Joseph Lister Correct answer-1867-Published the Antiseptic Principle in the Practice of Surgery
1869 -invented new sterilization technique for surgical suites
Robert Koch Correct answer-1876-Published report on life history and sporulation of Bacillus
anthracis
1877- Published methods for fixing bacteria on slides and staining for identification and comparison
1881- Developed method for obtaining pure cultures
1883-Discovered Vibrio cholerae and determined its routes of transmission
1905 - Awarded Nobel Prize
K Vierordt Correct answer-1877 - introduced coagulation time as an index of coagulative power of
blood
Paul Ehrlich Correct answer-1879-devised many methods of dryingfixing, and staining blood
smears Developed classification system for white blood cells based on morphology
Sir Almroth Edward Wright Correct answer-1890s - observed role of calcium in coagulation,
developed coagulometer
Sir Alexander Fleming Correct answer-Accidentally discovered penicillin (1928)
Gerhard Johannes Paul Domagk Correct answer-Discovered protonsil (a derivative of sulphanile
mide )
Otto Folin Correct answer-(between 1904-1922)
▪ Developed quantitative analytical methods for urine analytes
▪ Introduced Jaffe's alkaline picrate method for creatinine
▪ Introduced the colorimetric method for measuring epinephrine
▪ Published first normal values for uric acid, non-protein nitrogen, and protein in blood
Karl Landsteiner Correct answer-(1868-1943)
▪ Classified blood types into A, B, AB, and 0 (1909)
▪ Later contributed to the discovery of the Rh factor
Charles Drew, MD Correct answer-(1914-1950)
PASS
Have a qualified laboratory director, Participate, and be successful in, proficiency testing or external
quality assurance, Be performing patient testing Correct answer-To be eligible for CAP
Accreditation the lab must:
o Have a qualified laboratory director
o Participate, and be successful in, proficiency testing or external quality assurance
o Be performing patient testing
Key documents required for CAP Accreditation include Correct answer-o Quality Management Plan
o Chemical Hygiene Plan
o Document Control Process
o Competency Assessment Program
o Test Method Validation Documentation
o Laboratory Director Oversight Documentation
o Laboratory Information System (LIS)—if applicable
TJC, CAP, COLA, A2LA Correct answer-The four remaining agencies are more broad in scope
Laboratory Science Correct answer-Definition: The medical discipline by which clinical lab science
and technology are applied to the care of patients.
Boils Correct answer-Oldest known test was done on urine ( before 400 BC) Physicians poured
patient urine on the ground to see if it attracted insects If insects attracted , patient diagnosed with?
Hippocrates Correct answer-Who developed one of the earliest diagnostic protocols (300 BC)
Included tasting patient's urine, listening to lungs, observing outward appearances?
Rufus of Ephesus Correct answer-First description of hematuria was by? (around 50 BC)
Isaac Judaeus Correct answer-Middle Ages-guidelines for the use of urine as diagnostic tool
developed by? (AD 900 )
First book detailing urine color, density, quality, and sediment written around this time.
Hans and Zacharias Janssen Correct answer-Invention of the microscope by? In late 16th century
Anthanasius Kircher Correct answer-(1602 - 1680) early microscopist that studied causes of
diseases
Antonie van Leeuwenhoek Correct answer-(1632-1723) first to observe bacteria and protozoa
"Father of Microbiology"
Robert Hooke Correct answer-(1635 - 1703) used microscope to document the existence of cells in
vegetables
Marcello Malpighi Correct answer-(1628-1694) "founder of histology," studied embryology of
chicks
, Richard Lower Correct answer-Seventeenth century (1631 - 1691) experiments with blood
transfusions began in England by
William Hewson Correct answer-"Father of Hematology"
Discovered coagulable lymph now known as fibrinogen
Later discovered that fibrinogen is a plasma protein which is converted to fibrin in coagulation
J.W. Trichy Correct answer-Observed Urine sediment in febrile patients
Mathew Dobson Correct answer-Proved the sweetness of Urine in diabetes is caused by sugar
Francis Home Correct answer-Developed yeast test for sugar in urine of diabetic patients
Louis Pasteur Correct answer-1861 -Introduced concept of aerobic and anaerobic bacteria
1867 -Pasteurization ( sterilization by partial heat ) 1881 -Produced vaccine against anthrax
Joseph Lister Correct answer-1867-Published the Antiseptic Principle in the Practice of Surgery
1869 -invented new sterilization technique for surgical suites
Robert Koch Correct answer-1876-Published report on life history and sporulation of Bacillus
anthracis
1877- Published methods for fixing bacteria on slides and staining for identification and comparison
1881- Developed method for obtaining pure cultures
1883-Discovered Vibrio cholerae and determined its routes of transmission
1905 - Awarded Nobel Prize
K Vierordt Correct answer-1877 - introduced coagulation time as an index of coagulative power of
blood
Paul Ehrlich Correct answer-1879-devised many methods of dryingfixing, and staining blood
smears Developed classification system for white blood cells based on morphology
Sir Almroth Edward Wright Correct answer-1890s - observed role of calcium in coagulation,
developed coagulometer
Sir Alexander Fleming Correct answer-Accidentally discovered penicillin (1928)
Gerhard Johannes Paul Domagk Correct answer-Discovered protonsil (a derivative of sulphanile
mide )
Otto Folin Correct answer-(between 1904-1922)
▪ Developed quantitative analytical methods for urine analytes
▪ Introduced Jaffe's alkaline picrate method for creatinine
▪ Introduced the colorimetric method for measuring epinephrine
▪ Published first normal values for uric acid, non-protein nitrogen, and protein in blood
Karl Landsteiner Correct answer-(1868-1943)
▪ Classified blood types into A, B, AB, and 0 (1909)
▪ Later contributed to the discovery of the Rh factor
Charles Drew, MD Correct answer-(1914-1950)
