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NU 664D Exam 2025 With 100% Correct Answers

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clinical manifestations of primary amenorrhea - CORRECT ANSWERabsence of menarche by age 15 differential diagnoses for primary amenorrhea - CORRECT ANSWERpregnancy, turner syndrome, mullerian agenesis, delay of puberty, PCOS, weight loss, excessive exercise, anorexia diagnostic workup for primary amenorrhea - CORRECT ANSWERpelvic US, HCG, FSH, TSH, prolactin clinical manifestations of secondary amenorrhea - CORRECT ANSWERabsence of menses for more than 3 cycle intervals or 6 months in women who were previously menstruating what is the provera challenge? - CORRECT ANSWERstart with progestin for 10 days and then stop. if bleeding starts again, she has estrogen but is not ovulating. If she does not start bleeding again, she is ovulating but has outflow tract problem like scarring or adhesions. bleed = not ovulating no bleed = ovulating, scarring adhesions when is the provera challenge used? - CORRECT ANSWERfor diagnostic of secondary amenorrhea with normal labs and history of uterine instrumentation turner's syndrome clinical manifestations - CORRECT ANSWER1. hypogonadism -absent/non functioning sex chromosome (45X0) -> gonadal dysgenesis -> rudimentary, fibrosed ovaries -> primary amenorrhea in 80% (menopause before menarche) or early ovarian failure

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NU 664D Exam 2025 With 100% Correct
Answers

clinical manifestations of primary amenorrhea - CORRECT ANSWER✔✔absence of menarche by
age 15



differential diagnoses for primary amenorrhea - CORRECT ANSWER✔✔pregnancy, turner
syndrome, mullerian agenesis, delay of puberty, PCOS, weight loss, excessive exercise, anorexia



diagnostic workup for primary amenorrhea - CORRECT ANSWER✔✔pelvic US, HCG, FSH, TSH,
prolactin



clinical manifestations of secondary amenorrhea - CORRECT ANSWER✔✔absence of menses for
more than 3 cycle intervals or 6 months in women who were previously menstruating



what is the provera challenge? - CORRECT ANSWER✔✔start with progestin for 10 days and then
stop. if bleeding starts again, she has estrogen but is not ovulating. If she does not start bleeding
again, she is ovulating but has outflow tract problem like scarring or adhesions.

bleed = not ovulating

no bleed = ovulating, scarring adhesions



when is the provera challenge used? - CORRECT ANSWER✔✔for diagnostic of secondary
amenorrhea with normal labs and history of uterine instrumentation



turner's syndrome clinical manifestations - CORRECT ANSWER✔✔1. hypogonadism

-absent/non functioning sex chromosome (45X0) -> gonadal dysgenesis -> rudimentary, fibrosed
ovaries -> primary amenorrhea in 80% (menopause before menarche) or early ovarian failure

, with secondary amenorrhea (20%), delayed secondary sex characteristics (absence of breasts),
infertility in a majority of patients



2. physical exam

-short stature, webbed neck, prominent ears, posterior hairline, broad chest with hypoplastic
widely spaced nipples, (congenital lymphedema seen in neonates), short 4th metacarpals, high
arched palate, nail dysplasia, may have hearing loss



3. cardiovascular

-coarctation of the aorta

-MVP

-bicuspid aortic valves

-aortic dissection

-HTN



4. renal

-congenital abnormalities (horseshoe kidney)

-hydronephrosis



5. endocrine

-osteoporosis

-hypothyroidism

-DM

-dyslipidemia



6. GI

-telangiectasis (may present with GI bleeding)

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